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The map label for this gene is uppP

Identifier: 21673168

GI number: 21673168

Start: 345756

End: 346604

Strand: Reverse

Name: uppP

Synonym: CT0329

Alternate gene names: 21673168

Gene position: 346604-345756 (Counterclockwise)

Preceding gene: 21673169

Following gene: 21673167

Centisome position: 16.08

GC content: 60.66

Gene sequence:

>849_bases
ATGAACCTCTTCCAGGCCATCATCCTCGGCATCATTCAGGGTCTCACCGAATTTCTGCCAATCAGCAGCTCTGCGCACTT
GCGCATCGTCCCGGCTCTCATGGGATGGGGCGATCCGGGCGCGGCCTTCACGGCGATCATCCAGATCGGCACGCTCGCGG
CGGTGCTGATCTACTTCGCAAAGGACATTGTTTCGATCTCGGGCGCAGTGATCTCGGGTCTCGTCAAGGGCAAGCCGCTC
GGAACGGACGAGGCGCGGACGGGCTGGATGATCGCGGTCGGCACAATACCGATCGTCGTGTTCGGACTCACCTTCAAGCA
CGAGATCGAAACCGTTCTGCGCTCGCTCTACATCGTCTCCGCTTCGATGATCGGATTGGCACTTGTGCTCGTCGTAGCCG
AAAAGCACACCGCAAATCGCGCTCGAGACGGGCGCAGAGGCAAATCGATCAATGAACTCAGCTGGACGGACGCCATCATC
ATCGGACTTGCCCAGGCAATGGCGCTCATTCCCGGCTCTTCGCGCTCCGGCGTCACCATCACCGGCGGCCTGTTCCGCAA
CCTCGACCGCGAAACCGCCGCCCGTTTTTCGTTCCTGCTCTCGCTGCCATCGGTCTTCGCCGCCGGAATGCTCGAACTCT
ACCAGACCCGGCAGGAGATCATGTCATCGACGCACAACATGCTCAACCTCGCCGTCGCCACCATCGCCGCTTTCATCTTC
GGCTACCTCTCCATCGCCTTTCTGCTCAACTACCTCAAGCGCCACACCACCGGTATCTTCATCGCCTACCGCCTGATCCT
GGGCATCGGCCTCATCGTCATGATCGGCACTGGCCACCTGCTGCCGTGA

Upstream 100 bases:

>100_bases
GCCATCAGCCACCGTGGCCGCGCCGTCGTGGCGGCGGCAAAGCGCATCGGCGAGTACCTTTCACAATGCGGAATCCAGTA
ACAGAATCCACCACCATCCA

Downstream 100 bases:

>100_bases
AATCAAGGCAGGCGCGAGGCCTGCCCCTACAGATGACCGCTGCCCCTGTCACCGGATATGAAATTATCCTTCCACGCCTG
CGCCCTGACGCACCATCCGG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNLFQAIILGIIQGLTEFLPISSSAHLRIVPALMGWGDPGAAFTAIIQIGTLAAVLIYFAKDIVSISGAVISGLVKGKPL
GTDEARTGWMIAVGTIPIVVFGLTFKHEIETVLRSLYIVSASMIGLALVLVVAEKHTANRARDGRRGKSINELSWTDAII
IGLAQAMALIPGSSRSGVTITGGLFRNLDRETAARFSFLLSLPSVFAAGMLELYQTRQEIMSSTHNMLNLAVATIAAFIF
GYLSIAFLLNYLKRHTTGIFIAYRLILGIGLIVMIGTGHLLP

Sequences:

>Translated_282_residues
MNLFQAIILGIIQGLTEFLPISSSAHLRIVPALMGWGDPGAAFTAIIQIGTLAAVLIYFAKDIVSISGAVISGLVKGKPL
GTDEARTGWMIAVGTIPIVVFGLTFKHEIETVLRSLYIVSASMIGLALVLVVAEKHTANRARDGRRGKSINELSWTDAII
IGLAQAMALIPGSSRSGVTITGGLFRNLDRETAARFSFLLSLPSVFAAGMLELYQTRQEIMSSTHNMLNLAVATIAAFIF
GYLSIAFLLNYLKRHTTGIFIAYRLILGIGLIVMIGTGHLLP
>Mature_282_residues
MNLFQAIILGIIQGLTEFLPISSSAHLRIVPALMGWGDPGAAFTAIIQIGTLAAVLIYFAKDIVSISGAVISGLVKGKPL
GTDEARTGWMIAVGTIPIVVFGLTFKHEIETVLRSLYIVSASMIGLALVLVVAEKHTANRARDGRRGKSINELSWTDAII
IGLAQAMALIPGSSRSGVTITGGLFRNLDRETAARFSFLLSLPSVFAAGMLELYQTRQEIMSSTHNMLNLAVATIAAFIF
GYLSIAFLLNYLKRHTTGIFIAYRLILGIGLIVMIGTGHLLP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=271, Percent_Identity=34.3173431734317, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_CHLTE (Q8KFJ7)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661233.1
- GeneID:   1007991
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0329
- NMPDR:   fig|194439.1.peg.327
- TIGR:   CT0329
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- ProtClustDB:   PRK12554
- BioCyc:   CTEP194439:CT_0329-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30197; Mature: 30197

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc14e29c)-; HASH(0xc8726a4)-; HASH(0xcbe71ec)-; HASH(0xca34824)-; HASH(0xc830b50)-; HASH(0xc6b5774)-; HASH(0xc843b0c)-; HASH(0xc87292c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFQAIILGIIQGLTEFLPISSSAHLRIVPALMGWGDPGAAFTAIIQIGTLAAVLIYFA
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KDIVSISGAVISGLVKGKPLGTDEARTGWMIAVGTIPIVVFGLTFKHEIETVLRSLYIVS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASMIGLALVLVVAEKHTANRARDGRRGKSINELSWTDAIIIGLAQAMALIPGSSRSGVTI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TGGLFRNLDRETAARFSFLLSLPSVFAAGMLELYQTRQEIMSSTHNMLNLAVATIAAFIF
ECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLSIAFLLNYLKRHTTGIFIAYRLILGIGLIVMIGTGHLLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MNLFQAIILGIIQGLTEFLPISSSAHLRIVPALMGWGDPGAAFTAIIQIGTLAAVLIYFA
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KDIVSISGAVISGLVKGKPLGTDEARTGWMIAVGTIPIVVFGLTFKHEIETVLRSLYIVS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASMIGLALVLVVAEKHTANRARDGRRGKSINELSWTDAIIIGLAQAMALIPGSSRSGVTI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TGGLFRNLDRETAARFSFLLSLPSVFAAGMLELYQTRQEIMSSTHNMLNLAVATIAAFIF
ECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLSIAFLLNYLKRHTTGIFIAYRLILGIGLIVMIGTGHLLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12093901