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The map label for this gene is yggV [C]

Identifier: 21673169

GI number: 21673169

Start: 346624

End: 347304

Strand: Reverse

Name: yggV [C]

Synonym: CT0330

Alternate gene names: 21673169

Gene position: 347304-346624 (Counterclockwise)

Preceding gene: 21673170

Following gene: 21673168

Centisome position: 16.12

GC content: 64.17

Gene sequence:

>681_bases
ATGGAACCGAAACATCCCGAAATCACCATCGTTCTCGCCACCGGCAACAAGGACAAGGTTCGCGAGCTGAAGCCGGTACT
CGAAGCTCTCGCCTCCGGCATCCACGTCCGCTCGCTCCATGACCTCGGCCTCGACATCGACGTCGAGGAGACCGAACCAA
CCCTCGAAGGCAACGCGCGGCTCAAGGCCGATGCGATTTTCGAGCTGGTCGCGCCGCGCCTCGACTGGTTCATCGCGCTC
GCCGACGACACCGGCCTCGAAGTTGATGCGCTCGGCGGCGCGCCCGGCGTCTACTCTGCCCGCTACGCGCCCGTGCCGGA
AGGCGTCGCCCGCACCTACGAAGACAACGTCCGTCACCTGCTTTCAGAGATGCGCGGCAAGAGCAAGCGCACCGCCCGTT
TCCGGACAGTCATCGCCATGAAGGGCCGCCTGCCTGCGGCGAATGGCTCCGCGGTGGAGATCGAGGAAACCACGGACGGG
CACATCGACGGCCTCATCACCACGGAGCCGAAGGGCAACGGCGGTTTCGGCTACGATCCGGTCTTCGCACCGGAAGGAAT
GGATCGAACTTTCGCCCAGCTCGGTATCGACGAAAAAAACGCCATCAGCCACCGTGGCCGCGCCGTCGTGGCGGCGGCAA
AGCGCATCGGCGAGTACCTTTCACAATGCGGAATCCAGTAA

Upstream 100 bases:

>100_bases
GAGGAGGTGAGCATCGGCCACGCCATCATCTCACGCGCCGTGTTCATCGGCCTTCCGGCAGCCATCCAGGAAATCCTCGA
TCTCATCCGCCGGTAACGCT

Downstream 100 bases:

>100_bases
CAGAATCCACCACCATCCAATGAACCTCTTCCAGGCCATCATCCTCGGCATCATTCAGGGTCTCACCGAATTTCTGCCAA
TCAGCAGCTCTGCGCACTTG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEPKHPEITIVLATGNKDKVRELKPVLEALASGIHVRSLHDLGLDIDVEETEPTLEGNARLKADAIFELVAPRLDWFIAL
ADDTGLEVDALGGAPGVYSARYAPVPEGVARTYEDNVRHLLSEMRGKSKRTARFRTVIAMKGRLPAANGSAVEIEETTDG
HIDGLITTEPKGNGGFGYDPVFAPEGMDRTFAQLGIDEKNAISHRGRAVVAAAKRIGEYLSQCGIQ

Sequences:

>Translated_226_residues
MEPKHPEITIVLATGNKDKVRELKPVLEALASGIHVRSLHDLGLDIDVEETEPTLEGNARLKADAIFELVAPRLDWFIAL
ADDTGLEVDALGGAPGVYSARYAPVPEGVARTYEDNVRHLLSEMRGKSKRTARFRTVIAMKGRLPAANGSAVEIEETTDG
HIDGLITTEPKGNGGFGYDPVFAPEGMDRTFAQLGIDEKNAISHRGRAVVAAAKRIGEYLSQCGIQ
>Mature_226_residues
MEPKHPEITIVLATGNKDKVRELKPVLEALASGIHVRSLHDLGLDIDVEETEPTLEGNARLKADAIFELVAPRLDWFIAL
ADDTGLEVDALGGAPGVYSARYAPVPEGVARTYEDNVRHLLSEMRGKSKRTARFRTVIAMKGRLPAANGSAVEIEETTDG
HIDGLITTEPKGNGGFGYDPVFAPEGMDRTFAQLGIDEKNAISHRGRAVVAAAKRIGEYLSQCGIQ

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=202, Percent_Identity=42.5742574257426, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17556833, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920712, Length=133, Percent_Identity=33.0827067669173, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_CHLTE (Q8KFJ6)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661234.1
- ProteinModelPortal:   Q8KFJ6
- SMR:   Q8KFJ6
- GeneID:   1007992
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0330
- NMPDR:   fig|194439.1.peg.328
- TIGR:   CT0330
- HOGENOM:   HBG697237
- OMA:   YSKRYDQ
- ProtClustDB:   PRK14826
- BioCyc:   CTEP194439:CT_0330-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 24411; Mature: 24411

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKHPEITIVLATGNKDKVRELKPVLEALASGIHVRSLHDLGLDIDVEETEPTLEGNAR
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHCCCCEEECCCCCCCCCCCE
LKADAIFELVAPRLDWFIALADDTGLEVDALGGAPGVYSARYAPVPEGVARTYEDNVRHL
EHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LSEMRGKSKRTARFRTVIAMKGRLPAANGSAVEIEETTDGHIDGLITTEPKGNGGFGYDP
HHHHCCCCHHHHHHHEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCC
VFAPEGMDRTFAQLGIDEKNAISHRGRAVVAAAKRIGEYLSQCGIQ
CCCCCCCCHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEPKHPEITIVLATGNKDKVRELKPVLEALASGIHVRSLHDLGLDIDVEETEPTLEGNAR
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHCCCCEEECCCCCCCCCCCE
LKADAIFELVAPRLDWFIALADDTGLEVDALGGAPGVYSARYAPVPEGVARTYEDNVRHL
EHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LSEMRGKSKRTARFRTVIAMKGRLPAANGSAVEIEETTDGHIDGLITTEPKGNGGFGYDP
HHHHCCCCHHHHHHHEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCC
VFAPEGMDRTFAQLGIDEKNAISHRGRAVVAAAKRIGEYLSQCGIQ
CCCCCCCCHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901