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The map label for this gene is sucD [H]

Identifier: 21673108

GI number: 21673108

Start: 282091

End: 282993

Strand: Direct

Name: sucD [H]

Synonym: CT0269

Alternate gene names: 21673108

Gene position: 282091-282993 (Clockwise)

Preceding gene: 21673107

Following gene: 21673110

Centisome position: 13.09

GC content: 60.35

Gene sequence:

>903_bases
ATGAGCGTACTGGTCAATAAAGATACCCGCCTGGTCGTCCAGGGAATTACTGGCGGCGAGGGAACCTTCCACACCTCGCA
GATTCTGGAGTACGGCACCAACGTCGTCGCTGGCGTCACTCCTGGCAAGGGCGGAATACTCTATAACGGCAACGAAAAGG
ATCAATTCTGCCGTCCTGTGCCGGTCTTCGACACCGTGCAGGAGGCTGTGGACAAGGCCGAAGCCAACGCGACGGTGATC
TTCGTGCCCGCGCCATTTGCTGCCGACGCCATCATGGAGGCCGCCGCCGCCGGACTGAAGGTTATCATCTGCATCACCGA
AGGCATTCCGGTCAACGACATGATGAAAGCCTACAGCTACGTGCAGGCAAAAGGCGCGGTGCTGGTTGGCCCGAACTGCC
CCGGCGTCATCACCCCCGGCGAAGCCAAAGTCGGCATCATGCCGGGCTTCATCCACAAAAAAGGCACCATCGGCGTCGTT
TCGCGCAGCGGCACGTTGACTTACGAAGCGGTGCACCAGCTCACCGAAGTCGGTCTCGGCCAGTCCACCTGCATCGGTAT
CGGCGGCGACCCGATCATCGGCACCCGCTTCCTTGACGCCGTCAAGCTGTTCGCCAAGGATGATGAAACTGAGGGTCTCG
TCATGATCGGCGAGATCGGCGGCAGCGCTGAAGAGGAGGCCGCCGAGTACATCAAAAAGTACTTCAAAAAGCCGGTTGTG
GGCTTCATCGCGGGCCGCACTGCCCCTCCCGGCCGTCGCATGGGTCACGCGGGAGCGATCGTTTCAGGCGGCAAAGGCAC
CGCCGAAGAGAAGATCAAGGCAATGGAAGCTGCAGGCATCAAGGTTGTCGAAAACCCCGCCGACATCGGCGAAGCGATGC
TGAAAGCGCTTGGTAGAGCCTGA

Upstream 100 bases:

>100_bases
AGGGCAAGATGCTTGGCATTGCACGCCATCTCCAGACCTTGTGTCAGACAGCTCCGTCCAACTGACGGTTTTTTTTCATC
ACCAAAACGAATATCGGCAT

Downstream 100 bases:

>100_bases
AGGCTTTCGGTCCAGTTACAAAAAAGAGCGCTTTCGAGCGCTCTTTTTATTGGTGGGAGACAGATCAGTCAGAATCAGAC
GGATCTGAGAAAAACTACAA

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGILYNGNEKDQFCRPVPVFDTVQEAVDKAEANATVI
FVPAPFAADAIMEAAAAGLKVIICITEGIPVNDMMKAYSYVQAKGAVLVGPNCPGVITPGEAKVGIMPGFIHKKGTIGVV
SRSGTLTYEAVHQLTEVGLGQSTCIGIGGDPIIGTRFLDAVKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKKYFKKPVV
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEEKIKAMEAAGIKVVENPADIGEAMLKALGRA

Sequences:

>Translated_300_residues
MSVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGILYNGNEKDQFCRPVPVFDTVQEAVDKAEANATVI
FVPAPFAADAIMEAAAAGLKVIICITEGIPVNDMMKAYSYVQAKGAVLVGPNCPGVITPGEAKVGIMPGFIHKKGTIGVV
SRSGTLTYEAVHQLTEVGLGQSTCIGIGGDPIIGTRFLDAVKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKKYFKKPVV
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEEKIKAMEAAGIKVVENPADIGEAMLKALGRA
>Mature_299_residues
SVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGILYNGNEKDQFCRPVPVFDTVQEAVDKAEANATVIF
VPAPFAADAIMEAAAAGLKVIICITEGIPVNDMMKAYSYVQAKGAVLVGPNCPGVITPGEAKVGIMPGFIHKKGTIGVVS
RSGTLTYEAVHQLTEVGLGQSTCIGIGGDPIIGTRFLDAVKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKKYFKKPVVG
FIAGRTAPPGRRMGHAGAIVSGGKGTAEEKIKAMEAAGIKVVENPADIGEAMLKALGRA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=300, Percent_Identity=56.6666666666667, Blast_Score=290, Evalue=1e-78,
Organism=Homo sapiens, GI38569421, Length=311, Percent_Identity=27.6527331189711, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI38569423, Length=311, Percent_Identity=27.6527331189711, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786949, Length=297, Percent_Identity=60.2693602693603, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1786513, Length=212, Percent_Identity=29.2452830188679, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17553126, Length=301, Percent_Identity=55.8139534883721, Blast_Score=313, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI17550194, Length=301, Percent_Identity=55.1495016611296, Blast_Score=311, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17557344, Length=281, Percent_Identity=28.8256227758007, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551266, Length=310, Percent_Identity=27.741935483871, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=307, Percent_Identity=47.8827361563518, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI21356559, Length=303, Percent_Identity=53.4653465346535, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI28574296, Length=303, Percent_Identity=55.1155115511551, Blast_Score=300, Evalue=6e-82,
Organism=Drosophila melanogaster, GI281363477, Length=284, Percent_Identity=27.4647887323944, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363475, Length=284, Percent_Identity=27.4647887323944, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363473, Length=284, Percent_Identity=27.4647887323944, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31076; Mature: 30945

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGILYNGNEKDQFCRPV
CCEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHCCCCC
PVFDTVQEAVDKAEANATVIFVPAPFAADAIMEAAAAGLKVIICITEGIPVNDMMKAYSY
CHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHH
VQAKGAVLVGPNCPGVITPGEAKVGIMPGFIHKKGTIGVVSRSGTLTYEAVHQLTEVGLG
HHHCCCEEECCCCCCEECCCCCEEECCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCC
QSTCIGIGGDPIIGTRFLDAVKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKKYFKKPVV
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCE
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEEKIKAMEAAGIKVVENPADIGEAMLKALGRA
EEEECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLVNKDTRLVVQGITGGEGTFHTSQILEYGTNVVAGVTPGKGGILYNGNEKDQFCRPV
CEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHCCCCC
PVFDTVQEAVDKAEANATVIFVPAPFAADAIMEAAAAGLKVIICITEGIPVNDMMKAYSY
CHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHH
VQAKGAVLVGPNCPGVITPGEAKVGIMPGFIHKKGTIGVVSRSGTLTYEAVHQLTEVGLG
HHHCCCEEECCCCCCEECCCCCEEECCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCC
QSTCIGIGGDPIIGTRFLDAVKLFAKDDETEGLVMIGEIGGSAEEEAAEYIKKYFKKPVV
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCE
GFIAGRTAPPGRRMGHAGAIVSGGKGTAEEKIKAMEAAGIKVVENPADIGEAMLKALGRA
EEEECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]