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The map label for this gene is lolC [H]

Identifier: 21673097

GI number: 21673097

Start: 266860

End: 268128

Strand: Direct

Name: lolC [H]

Synonym: CT0258

Alternate gene names: 21673097

Gene position: 266860-268128 (Clockwise)

Preceding gene: 21673089

Following gene: 21673100

Centisome position: 12.38

GC content: 57.29

Gene sequence:

>1269_bases
ATGTTCAGAACCCTGTTCGATATAGCCATCAGGCACATTCTCGGGCGCAAGCGCCAGACGCTGACCACTATGCTTGCTGT
CTCTGTCAGTACGATGGTGCTCATCACCACCATTTCGCTGACGAGAGGGCTGCTCGATTCGTTCACTGAAACCATTATCG
ACGCGGCGCCGCATATCCGGATCAAAGGCGAGAAGATCGATCCGATGCCGACCAACCTTTTTGATTCGCTGGCTGTTTCG
AGAAAGGCTTTCGTGACCGACAATATCGGCAGGGATGAACCCGAGGAGGTGCGCAATTACGGGAGAATCCTCGATATTGT
TTCATCTCAGGCGTTCTCCGGAAAAGTCGTCGCCGCGTCGCCGTTCGTCGAGTCGCAGATCATTGCAGTCAAGGGGAATC
GCACCCAGCCGGTGGTGCTCAAGGGAGTGGATATTGATCGCGAAGATCGTATTAGCCACATCGGGCGCAGCCTTACCTCC
GGCGATCTGGTGCTTTTCAGAAAAACCCCAGATGCGCTGCTGGTCGGCAGTTCCGTAGCCACAGATCTCGGCGTGGAGCT
GAACGACCAGGTCACCATCATTACGCCCGACGGACGCAGTCGGCAGGGCAAGGTCACCGGAATATTTTTTACCGGTATTA
ACGCAGCCGATAACACGATTCTCTCGTCACTCAAACTCGGCCAGATTGTCGAGGGAATGCCACCCAACAAGGTTACCGGC
ATAGCGCTGAAGGTCGTTGATCCCCTCAATGATGCGCCACTGGCTCGGGATCTGGAGCGGATGACCGGCTACCGGTGCCT
GACCTGGCAGGAGGAGAATGCCAGTGTGCTGGTGCTGTTCAAGCGGATCGGTTCCATCGTCCTGTCGCTCGTGGGATTCG
TTGGCGTGGTGTCGGGATTTGGCGTGGCCAACATCCTTGTGACGACCGTGTTCGAGAAGAGCCGCGACATTGCCGTCATG
AAGTCGTTCGGCTTCTCGTCGGCGCAGATGGTGGGGCTGTTCGTCTTCGAGGGCTTTCTCGTCGGCCTCGGCGGCGCGCT
GACCGGCGGCATCTTGGCGACCGGCTCCATTGGCTTTCTGGCCAGCCTGCACATCGAAAGCTCGCAGGGGCCACTCACCA
AAAGCGGCTTTAGCATGTCGTGGAATCCCTGGTACTTTTTCTTTGTCATCGTTGTGACGGTCATCATCAGCACGATTGCG
GCAGCGATTCCTTCGCTCCGGGCAGCAAGGCTGGAGCCGGTGACGGTGTTGCGGGAGAGCAATTTGTAG

Upstream 100 bases:

>100_bases
TAGCGGCTCCCGGGTTGAACAATTTTTAGAGGTGCTCTGTAAAGTATAACTTATGGCAAATATACCATAACTTTTTTCGG
GCTTGTCCGGTTTGCGCCTT

Downstream 100 bases:

>100_bases
AGGGAAGATCGGCCGGCTCGGACTTATCCGACTGACCTGGCGAATTCTTCACCCCCGCGCCTTCCATTCTGCCGCGCTCC
GGGTGCTGCAATAAATACAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MFRTLFDIAIRHILGRKRQTLTTMLAVSVSTMVLITTISLTRGLLDSFTETIIDAAPHIRIKGEKIDPMPTNLFDSLAVS
RKAFVTDNIGRDEPEEVRNYGRILDIVSSQAFSGKVVAASPFVESQIIAVKGNRTQPVVLKGVDIDREDRISHIGRSLTS
GDLVLFRKTPDALLVGSSVATDLGVELNDQVTIITPDGRSRQGKVTGIFFTGINAADNTILSSLKLGQIVEGMPPNKVTG
IALKVVDPLNDAPLARDLERMTGYRCLTWQEENASVLVLFKRIGSIVLSLVGFVGVVSGFGVANILVTTVFEKSRDIAVM
KSFGFSSAQMVGLFVFEGFLVGLGGALTGGILATGSIGFLASLHIESSQGPLTKSGFSMSWNPWYFFFVIVVTVIISTIA
AAIPSLRAARLEPVTVLRESNL

Sequences:

>Translated_422_residues
MFRTLFDIAIRHILGRKRQTLTTMLAVSVSTMVLITTISLTRGLLDSFTETIIDAAPHIRIKGEKIDPMPTNLFDSLAVS
RKAFVTDNIGRDEPEEVRNYGRILDIVSSQAFSGKVVAASPFVESQIIAVKGNRTQPVVLKGVDIDREDRISHIGRSLTS
GDLVLFRKTPDALLVGSSVATDLGVELNDQVTIITPDGRSRQGKVTGIFFTGINAADNTILSSLKLGQIVEGMPPNKVTG
IALKVVDPLNDAPLARDLERMTGYRCLTWQEENASVLVLFKRIGSIVLSLVGFVGVVSGFGVANILVTTVFEKSRDIAVM
KSFGFSSAQMVGLFVFEGFLVGLGGALTGGILATGSIGFLASLHIESSQGPLTKSGFSMSWNPWYFFFVIVVTVIISTIA
AAIPSLRAARLEPVTVLRESNL
>Mature_422_residues
MFRTLFDIAIRHILGRKRQTLTTMLAVSVSTMVLITTISLTRGLLDSFTETIIDAAPHIRIKGEKIDPMPTNLFDSLAVS
RKAFVTDNIGRDEPEEVRNYGRILDIVSSQAFSGKVVAASPFVESQIIAVKGNRTQPVVLKGVDIDREDRISHIGRSLTS
GDLVLFRKTPDALLVGSSVATDLGVELNDQVTIITPDGRSRQGKVTGIFFTGINAADNTILSSLKLGQIVEGMPPNKVTG
IALKVVDPLNDAPLARDLERMTGYRCLTWQEENASVLVLFKRIGSIVLSLVGFVGVVSGFGVANILVTTVFEKSRDIAVM
KSFGFSSAQMVGLFVFEGFLVGLGGALTGGILATGSIGFLASLHIESSQGPLTKSGFSMSWNPWYFFFVIVVTVIISTIA
AAIPSLRAARLEPVTVLRESNL

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=358, Percent_Identity=24.5810055865922, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45475; Mature: 45475

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTLFDIAIRHILGRKRQTLTTMLAVSVSTMVLITTISLTRGLLDSFTETIIDAAPHIR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IKGEKIDPMPTNLFDSLAVSRKAFVTDNIGRDEPEEVRNYGRILDIVSSQAFSGKVVAAS
EECCCCCCCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
PFVESQIIAVKGNRTQPVVLKGVDIDREDRISHIGRSLTSGDLVLFRKTPDALLVGSSVA
CCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCEEEECCHHH
TDLGVELNDQVTIITPDGRSRQGKVTGIFFTGINAADNTILSSLKLGQIVEGMPPNKVTG
HHCCCEECCCEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEE
IALKVVDPLNDAPLARDLERMTGYRCLTWQEENASVLVLFKRIGSIVLSLVGFVGVVSGF
EEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCC
GVANILVTTVFEKSRDIAVMKSFGFSSAQMVGLFVFEGFLVGLGGALTGGILATGSIGFL
CHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCEE
ASLHIESSQGPLTKSGFSMSWNPWYFFFVIVVTVIISTIAAAIPSLRAARLEPVTVLRES
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECC
NL
CC
>Mature Secondary Structure
MFRTLFDIAIRHILGRKRQTLTTMLAVSVSTMVLITTISLTRGLLDSFTETIIDAAPHIR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IKGEKIDPMPTNLFDSLAVSRKAFVTDNIGRDEPEEVRNYGRILDIVSSQAFSGKVVAAS
EECCCCCCCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
PFVESQIIAVKGNRTQPVVLKGVDIDREDRISHIGRSLTSGDLVLFRKTPDALLVGSSVA
CCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCEEEECCHHH
TDLGVELNDQVTIITPDGRSRQGKVTGIFFTGINAADNTILSSLKLGQIVEGMPPNKVTG
HHCCCEECCCEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEE
IALKVVDPLNDAPLARDLERMTGYRCLTWQEENASVLVLFKRIGSIVLSLVGFVGVVSGF
EEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCC
GVANILVTTVFEKSRDIAVMKSFGFSSAQMVGLFVFEGFLVGLGGALTGGILATGSIGFL
CHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCEE
ASLHIESSQGPLTKSGFSMSWNPWYFFFVIVVTVIISTIAAAIPSLRAARLEPVTVLRES
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECC
NL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]