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The map label for this gene is argS [H]

Identifier: 21672856

GI number: 21672856

Start: 13318

End: 14973

Strand: Direct

Name: argS [H]

Synonym: CT0015

Alternate gene names: 21672856

Gene position: 13318-14973 (Clockwise)

Preceding gene: 21672855

Following gene: 21672863

Centisome position: 0.62

GC content: 59.12

Gene sequence:

>1656_bases
ATGCGAGCTTTTTTCCTCCCCTTCATTCAGGATGCCCTGCAAAAAGCGGGCATCGAGACCGACAAGGAGATTCAGATCGA
CAAGCCGAACGACAAAAAGTTCGGCGACTTCTCGACCAACATCGCCTTCCTTGTGGCCAAGGAGGCCCGGAAAAATCCGC
GCGAACTGGCGGGGCAACTCATCGGCCTGCTCGACTTTCCTGAAGGCACGGTGACGAAAACCGAGGTGGCCGGGCCGGGC
TTCATCAACTTCCATCTCGCTCCGGCCTTTTTCATGCGCTCGGCGCAGGAGGTGCTCGCAAAGGGCGAGGGGTTCGGCTG
CAATGAGTCTGGCAAGGGACTGAAAGCGATTGTCGAGTACGTGAGCGCCAACCCGACTGGGCCGCTTACCATCGGGCGTG
GACGCGGCGGCGTCTTGGGCGACTGCATCGCCAACCTGCTCGAAACGCAGGGCTACGAGGTGACGCGCGAGTACTACTTC
AACGATGCCGGACGCCAGATGCAGATTCTGGCCGAATCGGTGCGCTACCGCTACCTCGAAAAGTGCGGTCAGGTGATCGA
GTTCCCGGAGACGCACTACCAGGGCGACTACATCGGCGAAATCGCCGAGACGCTCTTCATCGAGCACGGCGACGGACTGG
CCGCGACCGACGAGTTGACGATCTTCAAGGAAGCCGCCGAGGCAGTCATCTTCAGCTCGATCCGCAAGACGCTCGAACGC
CTCTTGATCACGCACGACTCCTTCTTCAACGAGCACACGCTCTACCAGTCCCGCGAGGGGCAGCCGTCGGCGAACCAGCG
GGTGATCGACGCGCTCGACGCCAAAGGGTTCATCGGCAACTACGACGGCGCGACCTGGTTCATGACGACCAAGCTGGGGC
AGGAGAAGGACAAGGTGCTTATCAAATCTTCCGGCGATCCGAGCTACCGCTTGCCGGACATCGCCTACCACGTCACCAAG
TTCGAGCGTGGCTTCGACCTCATGGTGAACGTTTTTGGCGCGGATCACATCGACGAGTATCCCGACGTGCTTGAAGCATT
GAAGATTCTTGGCTACGACACCTCGAAGGTCAAGATCGCCATCAACCAGTTCGTCACCACCACGGTCGGTGGCCAGACGG
TCAAAATGTCCACCCGCAAGGGCAACGCCGACCTGCTCGACGACCTTATCGATGACGTCGGCGCGGACGCCACACGCCTC
TTCTTCATCATGCGCGGCAAGGATTCGCACCTCAACTTCGATGTCGAGCTGGCAAAAAAGCAGTCGAAAGACAACCCGGT
TTTCTACCTTCAGTACGCCCACGCGAGGATTTGCAGCCTCGTGCGCATGGCCGAAAAAGAGGTCGGCTTCGACGAGGCGA
CGGCTATTGGCGCAGGTTTGCCGCTGCTTTCGAGCGAGCCGGAGATCGACCTGGCTTCCGCATTGCTTGACTTCCCGGAT
ATCATCCAGTCAAGCCTCCGCCAGCTCGAACCGCAGAAGATGGTCGAGTACCTGCACACGGTTGCCGAACGATACCACAA
GTTCTATCAGGAGTGCCCGATTCTGAAGGCTGATGAACATCTCCGCACCGCTCGTCTCGAACTGTCACTCGCAGTACGTC
AGGTGCTGCGCAACGGATTCAAAATCCTCGGCATCTCGGCTCCGGAATCGATGTAA

Upstream 100 bases:

>100_bases
CAACGTCATCACGACCATCGACCATTTCGACGGACTCATGCCCGAAGCGTTGCTGGAGCTGAACCGCGCCGTCAAAACCA
TGTCTTAACGATTCATACCG

Downstream 100 bases:

>100_bases
GTAAGGGAAAATACTTTCGAGCCCTGATCAAGCGCTATACAGCTTGTGCTCGGCGATGTACTGCGCAATCGATGACGGCA
CAAACTGTCCAATTGGCTGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MRAFFLPFIQDALQKAGIETDKEIQIDKPNDKKFGDFSTNIAFLVAKEARKNPRELAGQLIGLLDFPEGTVTKTEVAGPG
FINFHLAPAFFMRSAQEVLAKGEGFGCNESGKGLKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYF
NDAGRQMQILAESVRYRYLEKCGQVIEFPETHYQGDYIGEIAETLFIEHGDGLAATDELTIFKEAAEAVIFSSIRKTLER
LLITHDSFFNEHTLYQSREGQPSANQRVIDALDAKGFIGNYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTK
FERGFDLMVNVFGADHIDEYPDVLEALKILGYDTSKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIDDVGADATRL
FFIMRGKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRMAEKEVGFDEATAIGAGLPLLSSEPEIDLASALLDFPD
IIQSSLRQLEPQKMVEYLHTVAERYHKFYQECPILKADEHLRTARLELSLAVRQVLRNGFKILGISAPESM

Sequences:

>Translated_551_residues
MRAFFLPFIQDALQKAGIETDKEIQIDKPNDKKFGDFSTNIAFLVAKEARKNPRELAGQLIGLLDFPEGTVTKTEVAGPG
FINFHLAPAFFMRSAQEVLAKGEGFGCNESGKGLKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYF
NDAGRQMQILAESVRYRYLEKCGQVIEFPETHYQGDYIGEIAETLFIEHGDGLAATDELTIFKEAAEAVIFSSIRKTLER
LLITHDSFFNEHTLYQSREGQPSANQRVIDALDAKGFIGNYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTK
FERGFDLMVNVFGADHIDEYPDVLEALKILGYDTSKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIDDVGADATRL
FFIMRGKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRMAEKEVGFDEATAIGAGLPLLSSEPEIDLASALLDFPD
IIQSSLRQLEPQKMVEYLHTVAERYHKFYQECPILKADEHLRTARLELSLAVRQVLRNGFKILGISAPESM
>Mature_551_residues
MRAFFLPFIQDALQKAGIETDKEIQIDKPNDKKFGDFSTNIAFLVAKEARKNPRELAGQLIGLLDFPEGTVTKTEVAGPG
FINFHLAPAFFMRSAQEVLAKGEGFGCNESGKGLKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYF
NDAGRQMQILAESVRYRYLEKCGQVIEFPETHYQGDYIGEIAETLFIEHGDGLAATDELTIFKEAAEAVIFSSIRKTLER
LLITHDSFFNEHTLYQSREGQPSANQRVIDALDAKGFIGNYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTK
FERGFDLMVNVFGADHIDEYPDVLEALKILGYDTSKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIDDVGADATRL
FFIMRGKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRMAEKEVGFDEATAIGAGLPLLSSEPEIDLASALLDFPD
IIQSSLRQLEPQKMVEYLHTVAERYHKFYQECPILKADEHLRTARLELSLAVRQVLRNGFKILGISAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=580, Percent_Identity=24.3103448275862, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI197100773, Length=523, Percent_Identity=23.9005736137667, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1788184, Length=608, Percent_Identity=27.1381578947368, Blast_Score=145, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320548, Length=574, Percent_Identity=27.3519163763066, Blast_Score=140, Evalue=5e-34,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 61454; Mature: 61454

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFFLPFIQDALQKAGIETDKEIQIDKPNDKKFGDFSTNIAFLVAKEARKNPRELAGQL
CCEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHH
IGLLDFPEGTVTKTEVAGPGFINFHLAPAFFMRSAQEVLAKGEGFGCNESGKGLKAIVEY
HHHEECCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYFNDAGRQMQILAESVRYRYLE
HHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHH
KCGQVIEFPETHYQGDYIGEIAETLFIEHGDGLAATDELTIFKEAAEAVIFSSIRKTLER
HHHHHHCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLITHDSFFNEHTLYQSREGQPSANQRVIDALDAKGFIGNYDGATWFMTTKLGQEKDKVL
HHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEE
IKSSGDPSYRLPDIAYHVTKFERGFDLMVNVFGADHIDEYPDVLEALKILGYDTSKVKIA
EECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEE
INQFVTTTVGGQTVKMSTRKGNADLLDDLIDDVGADATRLFFIMRGKDSHLNFDVELAKK
EEHHHHEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEHHC
QSKDNPVFYLQYAHARICSLVRMAEKEVGFDEATAIGAGLPLLSSEPEIDLASALLDFPD
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCHH
IIQSSLRQLEPQKMVEYLHTVAERYHKFYQECPILKADEHLRTARLELSLAVRQVLRNGF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KILGISAPESM
EEEEECCCCCC
>Mature Secondary Structure
MRAFFLPFIQDALQKAGIETDKEIQIDKPNDKKFGDFSTNIAFLVAKEARKNPRELAGQL
CCEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHH
IGLLDFPEGTVTKTEVAGPGFINFHLAPAFFMRSAQEVLAKGEGFGCNESGKGLKAIVEY
HHHEECCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYFNDAGRQMQILAESVRYRYLE
HHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHH
KCGQVIEFPETHYQGDYIGEIAETLFIEHGDGLAATDELTIFKEAAEAVIFSSIRKTLER
HHHHHHCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLITHDSFFNEHTLYQSREGQPSANQRVIDALDAKGFIGNYDGATWFMTTKLGQEKDKVL
HHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEE
IKSSGDPSYRLPDIAYHVTKFERGFDLMVNVFGADHIDEYPDVLEALKILGYDTSKVKIA
EECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEE
INQFVTTTVGGQTVKMSTRKGNADLLDDLIDDVGADATRLFFIMRGKDSHLNFDVELAKK
EEHHHHEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEHHC
QSKDNPVFYLQYAHARICSLVRMAEKEVGFDEATAIGAGLPLLSSEPEIDLASALLDFPD
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCHH
IIQSSLRQLEPQKMVEYLHTVAERYHKFYQECPILKADEHLRTARLELSLAVRQVLRNGF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KILGISAPESM
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA