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The map label for this gene is appB [H]

Identifier: 15899762

GI number: 15899762

Start: 2812735

End: 2813703

Strand: Direct

Name: appB [H]

Synonym: SSO3058

Alternate gene names: 15899762

Gene position: 2812735-2813703 (Clockwise)

Preceding gene: 15899761

Following gene: 15899763

Centisome position: 94.0

GC content: 37.05

Gene sequence:

>969_bases
GTGGCCACATTTTTTGTGGTCATAACAGTAAACTTCATATTACCAAGATTAATGCCAGGAAGCGCTCTTGCTGTAGTAAT
ATCCTTAATTGAAGGACAGAATGGTGTCGCTGCTACAGCTGGAAGTAGCGCGATAGCCCTTGAAGTAAGCCAGCTTGAAG
CTGCATTTGGTTTAACTCCTGCACCATGGTATGTACAGTATGCGCATTACATACAAGGAATATTTACGCTAAACCTAGGA
GCCAGCATAACATATTACCCAACTCCTGTACTCTCCATAATTTTAAGCGGACTACCTTGGACATTATTTCTAGTCGTAGT
TGGAGCAATCATAGCCTTCTTCCTTGGAAGTTATCTTGGAAGTATAGCCGGTTTTAACAGAAGAAGTAGAAAAGATTTAG
TAATATTAATAATTACATCAATCTTGGCTGCTTTGCCTTCATTCGTTATTTTAATGTATTTAGAAATGTGGTTATCCGTG
CAACATGGAATATTTCTTATAAGCTTCCCAAGCAAGATTAATACTAGTCCCAATTCAATTATGGCCCTTTCAAGATTTTA
TACACTCCCAATAATAGCGTTAATGTTTACATCATTATCGGGATTTGTGCTGGGAATGAGAAATAATATGCTACATACGA
TTAGAGATAATTATGTAACTTACGCAGAGATTCTTGGATTAGATCATAATCGAATTAGAAAGATGGTTTACAAAAACTCA
TTGTTACCAAATATAACCGCCTTTGCAATAATATTGGGTCTCGCAATAAGCCAGTCACTGACTGTAGAAGGTCTATTAAC
GACACCAGGTGTGGGATTCTTCTTCGGGTTAGCATTAACTTCAAAGGATTTACCCCTTCTCCAAGGGATTTTCTTATTTA
TCGCAATAATGTTAATACTTTCAATAGCTATAGTAGAAGCAATCTACACTATTCTAGATCCTAGAGCAAGGGTGAGTGAA
AGTGAGTAA

Upstream 100 bases:

>100_bases
GTATCAGAATGACAAAAGTTTATATACAATGGTAAAACATAATTATATTTGGTGATACCTGACGAAAGTAACTTATATTC
TCTACAAACTTGCAATTTAT

Downstream 100 bases:

>100_bases
ATATTACAATAGAATTAGAAAAGCATTATTTAATAATAAATTTATATTAGCTGGAATTGTAATAATCTTAGTAGACTTTG
CGATAGGGATAGTGGGAGCT

Product: maltose ABC transporter, permease

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MATFFVVITVNFILPRLMPGSALAVVISLIEGQNGVAATAGSSAIALEVSQLEAAFGLTPAPWYVQYAHYIQGIFTLNLG
ASITYYPTPVLSIILSGLPWTLFLVVVGAIIAFFLGSYLGSIAGFNRRSRKDLVILIITSILAALPSFVILMYLEMWLSV
QHGIFLISFPSKINTSPNSIMALSRFYTLPIIALMFTSLSGFVLGMRNNMLHTIRDNYVTYAEILGLDHNRIRKMVYKNS
LLPNITAFAIILGLAISQSLTVEGLLTTPGVGFFFGLALTSKDLPLLQGIFLFIAIMLILSIAIVEAIYTILDPRARVSE
SE

Sequences:

>Translated_322_residues
MATFFVVITVNFILPRLMPGSALAVVISLIEGQNGVAATAGSSAIALEVSQLEAAFGLTPAPWYVQYAHYIQGIFTLNLG
ASITYYPTPVLSIILSGLPWTLFLVVVGAIIAFFLGSYLGSIAGFNRRSRKDLVILIITSILAALPSFVILMYLEMWLSV
QHGIFLISFPSKINTSPNSIMALSRFYTLPIIALMFTSLSGFVLGMRNNMLHTIRDNYVTYAEILGLDHNRIRKMVYKNS
LLPNITAFAIILGLAISQSLTVEGLLTTPGVGFFFGLALTSKDLPLLQGIFLFIAIMLILSIAIVEAIYTILDPRARVSE
SE
>Mature_321_residues
ATFFVVITVNFILPRLMPGSALAVVISLIEGQNGVAATAGSSAIALEVSQLEAAFGLTPAPWYVQYAHYIQGIFTLNLGA
SITYYPTPVLSIILSGLPWTLFLVVVGAIIAFFLGSYLGSIAGFNRRSRKDLVILIITSILAALPSFVILMYLEMWLSVQ
HGIFLISFPSKINTSPNSIMALSRFYTLPIIALMFTSLSGFVLGMRNNMLHTIRDNYVTYAEILGLDHNRIRKMVYKNSL
LPNITAFAIILGLAISQSLTVEGLLTTPGVGFFFGLALTSKDLPLLQGIFLFIAIMLILSIAIVEAIYTILDPRARVSES
E

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789888, Length=260, Percent_Identity=28.0769230769231, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=25.6637168141593, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=24.9211356466877, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788504, Length=348, Percent_Identity=24.1379310344828, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=22.7848101265823, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35108; Mature: 34977

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFFVVITVNFILPRLMPGSALAVVISLIEGQNGVAATAGSSAIALEVSQLEAAFGLTP
CCEEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHHHHHCCCC
APWYVQYAHYIQGIFTLNLGASITYYPTPVLSIILSGLPWTLFLVVVGAIIAFFLGSYLG
CHHHHHHHHHHHHHHEEECCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SIAGFNRRSRKDLVILIITSILAALPSFVILMYLEMWLSVQHGIFLISFPSKINTSPNSI
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHH
MALSRFYTLPIIALMFTSLSGFVLGMRNNMLHTIRDNYVTYAEILGLDHNRIRKMVYKNS
HHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHC
LLPNITAFAIILGLAISQSLTVEGLLTTPGVGFFFGLALTSKDLPLLQGIFLFIAIMLIL
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SIAIVEAIYTILDPRARVSESE
HHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure 
ATFFVVITVNFILPRLMPGSALAVVISLIEGQNGVAATAGSSAIALEVSQLEAAFGLTP
CEEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHHHHHCCCC
APWYVQYAHYIQGIFTLNLGASITYYPTPVLSIILSGLPWTLFLVVVGAIIAFFLGSYLG
CHHHHHHHHHHHHHHEEECCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SIAGFNRRSRKDLVILIITSILAALPSFVILMYLEMWLSVQHGIFLISFPSKINTSPNSI
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHH
MALSRFYTLPIIALMFTSLSGFVLGMRNNMLHTIRDNYVTYAEILGLDHNRIRKMVYKNS
HHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHC
LLPNITAFAIILGLAISQSLTVEGLLTTPGVGFFFGLALTSKDLPLLQGIFLFIAIMLIL
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SIAIVEAIYTILDPRARVSESE
HHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]