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The map label for this gene is acd-5 [H]

Identifier: 15899477

GI number: 15899477

Start: 2518404

End: 2519600

Strand: Reverse

Name: acd-5 [H]

Synonym: SSO2761

Alternate gene names: 15899477

Gene position: 2519600-2518404 (Counterclockwise)

Preceding gene: 15899478

Following gene: 15899476

Centisome position: 84.2

GC content: 36.68

Gene sequence:

>1197_bases
ATGGTATTTCCTTTTAAGTCCTTGGAGGATTTTAAAGTAGAAATAACCCAAGATCATGAATTATTAAGAAGTGCAGTTAG
GGATTTTGCTGAAAATGTATTGGCGAAGTATGTGGAAAGAGGTGAAAAAGAATTAGATATCCCCTTAGAGGCTAAGCAAA
AGGCTAAGGAAATAGGTCTATATGGATTATTTGCAAGCCAAGATTTAGGGGGACAAGGTGCGGACTATTTGTCCTTACTT
ACAGCAACAGAGGAAATAGCTAGAATTTGGCCCTCTTTCAGCACATTTCTATTAATAAATTGGATGTTTATTTATGCGTT
ATCCAGATTTGGAAATGAAGAACTAAAGAAAAAATATGTAATACCAGTTGCCAATGGAGATAAAGTAGCAGCATTTGCTG
TTACTGAACCAGTAGCTGGTTCAGATGTAGCTGGTATAAAGACAACTGCAAAGAAATTAGATGGCGAATATGTAATAAAT
GGCAGGAAGATTTTCATAACCAATGGCGATATTGCGGATTATTACTTAATAGCCGCTAGAACTTCACCTCCAGATCCTAA
GGCTAGATGGAAAGGAATTTCGATGTTTGTTGTAGAGAAGGATGCTGTAAAACCAGTGAGTAGAATTGAAACTACTGGGC
TAAGATCTTCGCATACTGCCGAGATTTTATTGGAAGATGTAAAAGTACAGACTGAAAATCTACTTGGAGAGGAAGGTAAT
GGATTTAAATATGCAGTAAGTTCTTTTGATTTTGCTAGAACCATAGTTGCTTCACAAGCATTAGGGATTGGACAAGCCGC
TTTGGAGAAAATGATTAATTATTCACTTCAAAGATCTGCATTCGAAAAGAAACTAGCAGAATTTCAATTAGTACAGACTA
AAGTTTCTGAATCATTAGCAGATTTGGAGGTAGCTAGGCTAATAACATATTGGGCTGGGACGCTGTTTAGAAATGGGAAA
GAAAACGAATACACTGTTGCTGCTTCATTGGCTAAATTTATATCCACGGAATCTGCTGAGAGGATTATATTAAGGGCTAT
GAGTGTATATGGGGGTTACGGTGTTACTACATCTACCGGACTGGAGAGAATGTTAAGAGATTTACAAATTATGAAAACAT
ATGAAGGGACAAACGATATTCAAAGAATAAGCGCGGCAAGGTTCCTCTATAATAAATTCATTGGATATAAGGTGTGA

Upstream 100 bases:

>100_bases
AATGCAGATTACTTGGTTGTAGGCAACGCGATTGATTTCTGTAAAGCTATGTTGAGTAAGCTAGGGAAAAAATAATAATG
ATAAAAACGATTTTATTTTA

Downstream 100 bases:

>100_bases
CCGTGTATATTGGTAGTTCAGTTAAGAGAGTTGAAGATTTACGATTTTTAACTGGAAAAGGTAGATACATAGACGACATT
TACTTACCAAATATGCAATA

Product: Acyl-CoA dehydrogenase (acd-5)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MVFPFKSLEDFKVEITQDHELLRSAVRDFAENVLAKYVERGEKELDIPLEAKQKAKEIGLYGLFASQDLGGQGADYLSLL
TATEEIARIWPSFSTFLLINWMFIYALSRFGNEELKKKYVIPVANGDKVAAFAVTEPVAGSDVAGIKTTAKKLDGEYVIN
GRKIFITNGDIADYYLIAARTSPPDPKARWKGISMFVVEKDAVKPVSRIETTGLRSSHTAEILLEDVKVQTENLLGEEGN
GFKYAVSSFDFARTIVASQALGIGQAALEKMINYSLQRSAFEKKLAEFQLVQTKVSESLADLEVARLITYWAGTLFRNGK
ENEYTVAASLAKFISTESAERIILRAMSVYGGYGVTTSTGLERMLRDLQIMKTYEGTNDIQRISAARFLYNKFIGYKV

Sequences:

>Translated_398_residues
MVFPFKSLEDFKVEITQDHELLRSAVRDFAENVLAKYVERGEKELDIPLEAKQKAKEIGLYGLFASQDLGGQGADYLSLL
TATEEIARIWPSFSTFLLINWMFIYALSRFGNEELKKKYVIPVANGDKVAAFAVTEPVAGSDVAGIKTTAKKLDGEYVIN
GRKIFITNGDIADYYLIAARTSPPDPKARWKGISMFVVEKDAVKPVSRIETTGLRSSHTAEILLEDVKVQTENLLGEEGN
GFKYAVSSFDFARTIVASQALGIGQAALEKMINYSLQRSAFEKKLAEFQLVQTKVSESLADLEVARLITYWAGTLFRNGK
ENEYTVAASLAKFISTESAERIILRAMSVYGGYGVTTSTGLERMLRDLQIMKTYEGTNDIQRISAARFLYNKFIGYKV
>Mature_398_residues
MVFPFKSLEDFKVEITQDHELLRSAVRDFAENVLAKYVERGEKELDIPLEAKQKAKEIGLYGLFASQDLGGQGADYLSLL
TATEEIARIWPSFSTFLLINWMFIYALSRFGNEELKKKYVIPVANGDKVAAFAVTEPVAGSDVAGIKTTAKKLDGEYVIN
GRKIFITNGDIADYYLIAARTSPPDPKARWKGISMFVVEKDAVKPVSRIETTGLRSSHTAEILLEDVKVQTENLLGEEGN
GFKYAVSSFDFARTIVASQALGIGQAALEKMINYSLQRSAFEKKLAEFQLVQTKVSESLADLEVARLITYWAGTLFRNGK
ENEYTVAASLAKFISTESAERIILRAMSVYGGYGVTTSTGLERMLRDLQIMKTYEGTNDIQRISAARFLYNKFIGYKV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=384, Percent_Identity=35.6770833333333, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=35.7512953367876, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=35.7512953367876, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI4501859, Length=391, Percent_Identity=33.5038363171356, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI21361497, Length=394, Percent_Identity=31.2182741116751, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI7656849, Length=386, Percent_Identity=29.7927461139896, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=30.4909560723514, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI226958412, Length=385, Percent_Identity=30.6493506493506, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=32.3442136498516, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI76496475, Length=401, Percent_Identity=29.925187032419, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4557235, Length=398, Percent_Identity=29.8994974874372, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=26.1324041811847, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=26.1324041811847, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=25.9842519685039, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI7669494, Length=369, Percent_Identity=25.4742547425474, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38505218, Length=343, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI87081958, Length=378, Percent_Identity=28.8359788359788, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786223, Length=388, Percent_Identity=27.5773195876289, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87082384, Length=281, Percent_Identity=26.6903914590747, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=35.7702349869452, Blast_Score=214, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=32.7225130890052, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17534899, Length=384, Percent_Identity=31.7708333333333, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17506239, Length=397, Percent_Identity=29.9748110831234, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=30.2872062663185, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17538396, Length=396, Percent_Identity=28.5353535353535, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=31.8181818181818, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17533517, Length=383, Percent_Identity=30.0261096605744, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=330, Percent_Identity=30, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71982178, Length=290, Percent_Identity=30.6896551724138, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=32.5088339222615, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17505929, Length=324, Percent_Identity=28.3950617283951, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=31.7596566523605, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=29.9003322259136, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17534353, Length=385, Percent_Identity=27.5324675324675, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=250, Percent_Identity=26.8, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=341, Percent_Identity=26.9794721407625, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17531913, Length=201, Percent_Identity=24.3781094527363, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=314, Percent_Identity=24.8407643312102, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=314, Percent_Identity=24.8407643312102, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=35.9249329758713, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24646207, Length=371, Percent_Identity=34.2318059299191, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=35.6200527704486, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=31.758530183727, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355753, Length=396, Percent_Identity=29.5454545454545, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281363737, Length=283, Percent_Identity=36.3957597173145, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI19920834, Length=393, Percent_Identity=27.4809160305344, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24652780, Length=337, Percent_Identity=20.4747774480712, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44364; Mature: 44364

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFPFKSLEDFKVEITQDHELLRSAVRDFAENVLAKYVERGEKELDIPLEAKQKAKEIGL
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCE
YGLFASQDLGGQGADYLSLLTATEEIARIWPSFSTFLLINWMFIYALSRFGNEELKKKYV
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCEEE
IPVANGDKVAAFAVTEPVAGSDVAGIKTTAKKLDGEYVINGRKIFITNGDIADYYLIAAR
EEECCCCEEEEEEEECCCCCCCCCCHHHHHHHCCCCEEECCEEEEEECCCCCEEEEEEEC
TSPPDPKARWKGISMFVVEKDAVKPVSRIETTGLRSSHTAEILLEDVKVQTENLLGEEGN
CCCCCCCHHHCCEEEEEEECHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GFKYAVSSFDFARTIVASQALGIGQAALEKMINYSLQRSAFEKKLAEFQLVQTKVSESLA
CEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLEVARLITYWAGTLFRNGKENEYTVAASLAKFISTESAERIILRAMSVYGGYGVTTSTG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHH
LERMLRDLQIMKTYEGTNDIQRISAARFLYNKFIGYKV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVFPFKSLEDFKVEITQDHELLRSAVRDFAENVLAKYVERGEKELDIPLEAKQKAKEIGL
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCE
YGLFASQDLGGQGADYLSLLTATEEIARIWPSFSTFLLINWMFIYALSRFGNEELKKKYV
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCEEE
IPVANGDKVAAFAVTEPVAGSDVAGIKTTAKKLDGEYVINGRKIFITNGDIADYYLIAAR
EEECCCCEEEEEEEECCCCCCCCCCHHHHHHHCCCCEEECCEEEEEECCCCCEEEEEEEC
TSPPDPKARWKGISMFVVEKDAVKPVSRIETTGLRSSHTAEILLEDVKVQTENLLGEEGN
CCCCCCCHHHCCEEEEEEECHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GFKYAVSSFDFARTIVASQALGIGQAALEKMINYSLQRSAFEKKLAEFQLVQTKVSESLA
CEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLEVARLITYWAGTLFRNGKENEYTVAASLAKFISTESAERIILRAMSVYGGYGVTTSTG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHH
LERMLRDLQIMKTYEGTNDIQRISAARFLYNKFIGYKV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]