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The map label for this gene is tpa [H]

Identifier: 15899435

GI number: 15899435

Start: 2473023

End: 2474357

Strand: Direct

Name: tpa [H]

Synonym: SSO2720

Alternate gene names: 15899435

Gene position: 2473023-2474357 (Clockwise)

Preceding gene: 15899434

Following gene: 15899436

Centisome position: 82.65

GC content: 37.75

Gene sequence:

>1335_bases
ATGGGAGAAATAGAAGATAAGAAAATTATTAGGGATCATACTTTCAAAACGTGGAGTAAACAAAAGGGATGGGATCCCAT
AATCGTATCAAGTGCAAAGGGAGTCTACTTTTATGATGTGGAGGGAAAGAAATATTTAGACTTTTCATCGCAATTCGTTA
ATGTAAATTTGGGATATGGAAATGAAAGGGTTATAAACAGTATAAAGGAACAGCTTGATAGGTTACAGTATATTAATCCC
TCATTCGGTGCGGATATTAGAGTTAAGGCTACAAAAGCTTTACTTAAGGTTATGCCTAGGAATATTAGTAAGTTTTTTTA
CTCTACCTCTGGCACTGAGGCTAATGAAGCTGCAATTAAGATATCTAGGTTTTACAAGAAGCCGAGATATAAGATTCTGG
CTAGATATAGGTCATACCATGGATCCACTGAGGGATCCATATCTTTAACTGGGGATTATAGAAGGTGGTTTGTTGAACCC
AACACTATGAATGGAGTAGTGCGAATACCAGAACCTTACTGCTTTAGGTGTCCACTTAAGCTAAAATACCCTGATTGTGG
AATAGCATGTGCGACCTATGTTGATTACGTTATTAGGCAAGAAAAGAACGTCGCTGCTATGATTATTGAACCAATAACCG
GTACCAATGGTGTTATAGTACCTCCTAAAGAATATATGCCTTTAATAAGGAAGATAGCTAAGGAAAATGACGTTTTGTTT
ATAGCGGATGAAGTTATGACTGGCTGGGGAAGAGTAGGGGAGTGGTTCGCTGTAAACTTATGGGATATTCACCCTGACAT
TTTAACTACTGCCAAGGGTGCTTCTGCATCTTACGTCCCAATTGGAATAACTGGAGTAAGTAAAGAGATAGGAGAGTTTT
TTGAAGACGAGGTTTTTGCGCATGGACATACTTTTGAGGCTCATCCAGTTTCACTGTCAGCTATCCCAGCGGTAATAGAA
GAGTATGAAAGATTGAACATTCTTTCTCATGTGAAAGTAATGGGGGATTATTTGGGTAAGAGGCTTCAAGAGTTAAAGGA
GAGGCACAGAAGTATCGGCGATGTGAGAGGAGTTGGGTTATTCTGGGCAATTGAGTTGGTAAAGGATAAAAATAATACTC
CATTTGGTGGGTATGATGATAAATATGAGGGTTATACTACATTTGTTGACGTTTTAGCTAGGAGACTCCTAATAGAGAAA
AATACTTATGTCTATAACGGTCCCTCATGGTTTATAATCTCACCTCCTTTAATAATAAATAAAGAGGAAATAGACGAGGG
CGTAGATGCTATAGATGATATACTAAAGGAGGCTGATAAAGAATTTAATAATTAG

Upstream 100 bases:

>100_bases
AGAACTTTTAAACAGTTGATGATTATATTCAATTTTTGTACTAATTTTAATCATCTGTGTAAAAAGCTTATAACCCTTGC
TTATAAAAATAAGATAGAAT

Downstream 100 bases:

>100_bases
TAATAATAGAACTACTATAGTTAATATGAAAGCAGTTCCTCAAATTAATAATTTTTTATCTTAATGGGGGTTAAGGGGGC
AGAAGACTAATCCGTAACGG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MGEIEDKKIIRDHTFKTWSKQKGWDPIIVSSAKGVYFYDVEGKKYLDFSSQFVNVNLGYGNERVINSIKEQLDRLQYINP
SFGADIRVKATKALLKVMPRNISKFFYSTSGTEANEAAIKISRFYKKPRYKILARYRSYHGSTEGSISLTGDYRRWFVEP
NTMNGVVRIPEPYCFRCPLKLKYPDCGIACATYVDYVIRQEKNVAAMIIEPITGTNGVIVPPKEYMPLIRKIAKENDVLF
IADEVMTGWGRVGEWFAVNLWDIHPDILTTAKGASASYVPIGITGVSKEIGEFFEDEVFAHGHTFEAHPVSLSAIPAVIE
EYERLNILSHVKVMGDYLGKRLQELKERHRSIGDVRGVGLFWAIELVKDKNNTPFGGYDDKYEGYTTFVDVLARRLLIEK
NTYVYNGPSWFIISPPLIINKEEIDEGVDAIDDILKEADKEFNN

Sequences:

>Translated_444_residues
MGEIEDKKIIRDHTFKTWSKQKGWDPIIVSSAKGVYFYDVEGKKYLDFSSQFVNVNLGYGNERVINSIKEQLDRLQYINP
SFGADIRVKATKALLKVMPRNISKFFYSTSGTEANEAAIKISRFYKKPRYKILARYRSYHGSTEGSISLTGDYRRWFVEP
NTMNGVVRIPEPYCFRCPLKLKYPDCGIACATYVDYVIRQEKNVAAMIIEPITGTNGVIVPPKEYMPLIRKIAKENDVLF
IADEVMTGWGRVGEWFAVNLWDIHPDILTTAKGASASYVPIGITGVSKEIGEFFEDEVFAHGHTFEAHPVSLSAIPAVIE
EYERLNILSHVKVMGDYLGKRLQELKERHRSIGDVRGVGLFWAIELVKDKNNTPFGGYDDKYEGYTTFVDVLARRLLIEK
NTYVYNGPSWFIISPPLIINKEEIDEGVDAIDDILKEADKEFNN
>Mature_443_residues
GEIEDKKIIRDHTFKTWSKQKGWDPIIVSSAKGVYFYDVEGKKYLDFSSQFVNVNLGYGNERVINSIKEQLDRLQYINPS
FGADIRVKATKALLKVMPRNISKFFYSTSGTEANEAAIKISRFYKKPRYKILARYRSYHGSTEGSISLTGDYRRWFVEPN
TMNGVVRIPEPYCFRCPLKLKYPDCGIACATYVDYVIRQEKNVAAMIIEPITGTNGVIVPPKEYMPLIRKIAKENDVLFI
ADEVMTGWGRVGEWFAVNLWDIHPDILTTAKGASASYVPIGITGVSKEIGEFFEDEVFAHGHTFEAHPVSLSAIPAVIEE
YERLNILSHVKVMGDYLGKRLQELKERHRSIGDVRGVGLFWAIELVKDKNNTPFGGYDDKYEGYTTFVDVLARRLLIEKN
TYVYNGPSWFIISPPLIINKEEIDEGVDAIDDILKEADKEFNN

Specific function: Catalyzes the degradation of taurine into alanine and sulfoacetaldehyde. Can also transaminate hypotaurine (2- aminosulfinate), beta-alanine and with low activity cysteine and 3-aminopropanesulfonate. In addition to pyruvate, 2-ketobutyrate and oxaloaceta

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=28.5046728971963, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=28.7383177570093, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=27.2517321016166, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24119277, Length=429, Percent_Identity=27.7389277389277, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4557809, Length=414, Percent_Identity=27.2946859903382, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI226442709, Length=396, Percent_Identity=28.030303030303, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI284507298, Length=330, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI188536080, Length=384, Percent_Identity=24.4791666666667, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679950, Length=384, Percent_Identity=24.4791666666667, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679946, Length=384, Percent_Identity=24.4791666666667, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=28.8607594936709, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1789016, Length=421, Percent_Identity=28.7410926365796, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1789759, Length=405, Percent_Identity=25.679012345679, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788044, Length=411, Percent_Identity=26.2773722627737, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=26.1904761904762, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786349, Length=400, Percent_Identity=25.75, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=23.5849056603774, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=29.1954022988506, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=27.6255707762557, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=413, Percent_Identity=26.1501210653753, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25144274, Length=232, Percent_Identity=30.6034482758621, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=450, Percent_Identity=22.4444444444444, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323470, Length=425, Percent_Identity=28.9411764705882, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324432, Length=436, Percent_Identity=27.5229357798165, Blast_Score=133, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21356575, Length=444, Percent_Identity=27.9279279279279, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI161085790, Length=435, Percent_Identity=27.1264367816092, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI28574759, Length=372, Percent_Identity=28.7634408602151, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21357415, Length=413, Percent_Identity=25.6658595641646, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366494, Length=382, Percent_Identity=25.3926701570681, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667139, Length=382, Percent_Identity=25.3926701570681, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667143, Length=382, Percent_Identity=25.3926701570681, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.77 [H]

Molecular weight: Translated: 50629; Mature: 50498

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIEDKKIIRDHTFKTWSKQKGWDPIIVSSAKGVYFYDVEGKKYLDFSSQFVNVNLGYG
CCCCCCCHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEECCCCEEEEEEECCC
NERVINSIKEQLDRLQYINPSFGADIRVKATKALLKVMPRNISKFFYSTSGTEANEAAIK
CHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ISRFYKKPRYKILARYRSYHGSTEGSISLTGDYRRWFVEPNTMNGVVRIPEPYCFRCPLK
HHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCCEEECCCCCEEECCEE
LKYPDCGIACATYVDYVIRQEKNVAAMIIEPITGTNGVIVPPKEYMPLIRKIAKENDVLF
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCEEE
IADEVMTGWGRVGEWFAVNLWDIHPDILTTAKGASASYVPIGITGVSKEIGEFFEDEVFA
EEHHHHHCCCCCCCEEEEEEEECCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
HGHTFEAHPVSLSAIPAVIEEYERLNILSHVKVMGDYLGKRLQELKERHRSIGDVRGVGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FWAIELVKDKNNTPFGGYDDKYEGYTTFVDVLARRLLIEKNTYVYNGPSWFIISPPLIIN
HEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCEEEE
KEEIDEGVDAIDDILKEADKEFNN
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEIEDKKIIRDHTFKTWSKQKGWDPIIVSSAKGVYFYDVEGKKYLDFSSQFVNVNLGYG
CCCCCCHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEEECCCCEEEEEEECCC
NERVINSIKEQLDRLQYINPSFGADIRVKATKALLKVMPRNISKFFYSTSGTEANEAAIK
CHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ISRFYKKPRYKILARYRSYHGSTEGSISLTGDYRRWFVEPNTMNGVVRIPEPYCFRCPLK
HHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCCEEECCCCCEEECCEE
LKYPDCGIACATYVDYVIRQEKNVAAMIIEPITGTNGVIVPPKEYMPLIRKIAKENDVLF
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCEEE
IADEVMTGWGRVGEWFAVNLWDIHPDILTTAKGASASYVPIGITGVSKEIGEFFEDEVFA
EEHHHHHCCCCCCCEEEEEEEECCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
HGHTFEAHPVSLSAIPAVIEEYERLNILSHVKVMGDYLGKRLQELKERHRSIGDVRGVGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
FWAIELVKDKNNTPFGGYDDKYEGYTTFVDVLARRLLIEKNTYVYNGPSWFIISPPLIIN
HEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCEEEE
KEEIDEGVDAIDDILKEADKEFNN
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11082195 [H]