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The map label for this gene is exuT [H]

Identifier: 15899433

GI number: 15899433

Start: 2470122

End: 2471381

Strand: Reverse

Name: exuT [H]

Synonym: SSO2718

Alternate gene names: 15899433

Gene position: 2471381-2470122 (Counterclockwise)

Preceding gene: 15899437

Following gene: 15899432

Centisome position: 82.59

GC content: 36.75

Gene sequence:

>1260_bases
ATGAAAGGAAATCTAAGATGGAAGATCGTTCTGATTATATTTGCATTAATTATAGTAGACTACATAGATAGGGGGCTAAT
CAATACTGCACTACCAGTACTAAAAAGTGAATTCCACATAAGTTCTTTTGAAGCTGGAATAATTGGAGATGGTTTCACTT
TTGGATATCTTATAATGAACCCTTTAGTTGGTTATTTTTTGGACAAGTACGGACCTAAAAGGGTTTTTAGTAGATTTGCA
ATCCTTTGGGGGGCTGTACAAGCTATTAATGTATTTGCTTTCTCAACTTTTTACTTTATAGTAACTAGAGTATTATTGGG
AATTGGAGAAGCAGTAGGTTTCCCAGGAGTTACAAAGATAGTCGCAAATTGGCTTAGAAAAGACGAAAAGGCTAGAGGTG
GTACCATTTCAGATTCTGGGGTGAATTTAGGGATAGTTTTCGGTTCCTTATTTATGTTGGGATTGTTTGCAATAATTCCT
AACCAAGAATTAGCGTGGAGGTTGGGATTTTTAGTTAGTGGTCTTTTGGCTATAATTCTAGCTATCATATTAGGTCGCCT
TTTGTATGATTTACCAGAACAGCATCCGAAGATTTCTAAGGAAGAATTAGACTACATTTTGTCAGGCAGAGAAAAGGTTG
GCGTGAAAACTAAGCTTCCATTGTCATATTGGTTAAGAAGTAAAAATTACTGGGGTTATATGCAAGGTTTGGGTGCGCAA
GCTGGGATATTCTTCGGTCTATTTACTTGGTTGCCTTTATATCTTTTTTACGCTAGACATCTTTCTCTATCGTTTACATT
AGAATACACTGCATTGATTTGGAGCTTTGGCTTCATAGGAGAGTTAGTAGGAGGTTATGTCGTTGACAAATTAATTAAGA
GAAATCCCAATTTAGGTTTCAAAGTAGGATTTGCGGTTAGCTCTTTGGCAGTAACTATAGGTCTTGCAGCTGCTACTCTC
ATTTCTTCACCGATAGAAGCAGTTGAAATACTAATGGTAACTTTCTTCTTCCTAAGATGGTCGGGGATACAATGGGCAGC
ACCATCCTTTCTAGTTTCTACTGAATTAGCTGGTCAATTTGGTGGTCATATTGGCTTTTGGGAAACTCTATGGGGTATAA
TAGTACCAATAGTATTTGGTGCTACTGTGGAAGTCACCAAAGCATATCTCTTAGGAATGGAAATCTTAATTGGGATAGGT
CTTATATACTTCATCGGAACAGTAATAATAACTAACTATAGGCAAATAAAGGTGAGCTAA

Upstream 100 bases:

>100_bases
TAAGTATATATCGTAAATTTAAACTATTTACTATCATTCAGTCTTTTTAATAAACTTGTAAACGTAATAACTTATATATA
TCTAATTATATTCTTCACTA

Downstream 100 bases:

>100_bases
GATTGTGGAAGGTATTTTTTATTAATGGAAATTTCGTTAAAGAAAATGTTAGAGATGAGCTTCCTAAACCGAATGAAGTA
AAGGTTTTTCCTAAATACAT

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKGNLRWKIVLIIFALIIVDYIDRGLINTALPVLKSEFHISSFEAGIIGDGFTFGYLIMNPLVGYFLDKYGPKRVFSRFA
ILWGAVQAINVFAFSTFYFIVTRVLLGIGEAVGFPGVTKIVANWLRKDEKARGGTISDSGVNLGIVFGSLFMLGLFAIIP
NQELAWRLGFLVSGLLAIILAIILGRLLYDLPEQHPKISKEELDYILSGREKVGVKTKLPLSYWLRSKNYWGYMQGLGAQ
AGIFFGLFTWLPLYLFYARHLSLSFTLEYTALIWSFGFIGELVGGYVVDKLIKRNPNLGFKVGFAVSSLAVTIGLAAATL
ISSPIEAVEILMVTFFFLRWSGIQWAAPSFLVSTELAGQFGGHIGFWETLWGIIVPIVFGATVEVTKAYLLGMEILIGIG
LIYFIGTVIITNYRQIKVS

Sequences:

>Translated_419_residues
MKGNLRWKIVLIIFALIIVDYIDRGLINTALPVLKSEFHISSFEAGIIGDGFTFGYLIMNPLVGYFLDKYGPKRVFSRFA
ILWGAVQAINVFAFSTFYFIVTRVLLGIGEAVGFPGVTKIVANWLRKDEKARGGTISDSGVNLGIVFGSLFMLGLFAIIP
NQELAWRLGFLVSGLLAIILAIILGRLLYDLPEQHPKISKEELDYILSGREKVGVKTKLPLSYWLRSKNYWGYMQGLGAQ
AGIFFGLFTWLPLYLFYARHLSLSFTLEYTALIWSFGFIGELVGGYVVDKLIKRNPNLGFKVGFAVSSLAVTIGLAAATL
ISSPIEAVEILMVTFFFLRWSGIQWAAPSFLVSTELAGQFGGHIGFWETLWGIIVPIVFGATVEVTKAYLLGMEILIGIG
LIYFIGTVIITNYRQIKVS
>Mature_419_residues
MKGNLRWKIVLIIFALIIVDYIDRGLINTALPVLKSEFHISSFEAGIIGDGFTFGYLIMNPLVGYFLDKYGPKRVFSRFA
ILWGAVQAINVFAFSTFYFIVTRVLLGIGEAVGFPGVTKIVANWLRKDEKARGGTISDSGVNLGIVFGSLFMLGLFAIIP
NQELAWRLGFLVSGLLAIILAIILGRLLYDLPEQHPKISKEELDYILSGREKVGVKTKLPLSYWLRSKNYWGYMQGLGAQ
AGIFFGLFTWLPLYLFYARHLSLSFTLEYTALIWSFGFIGELVGGYVVDKLIKRNPNLGFKVGFAVSSLAVTIGLAAATL
ISSPIEAVEILMVTFFFLRWSGIQWAAPSFLVSTELAGQFGGHIGFWETLWGIIVPIVFGATVEVTKAYLLGMEILIGIG
LIYFIGTVIITNYRQIKVS

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI148743791, Length=254, Percent_Identity=27.1653543307087, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1789152, Length=414, Percent_Identity=27.0531400966184, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87082320, Length=393, Percent_Identity=26.7175572519084, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1789515, Length=413, Percent_Identity=26.1501210653753, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI2367379, Length=400, Percent_Identity=25, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI2367193, Length=291, Percent_Identity=27.1477663230241, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=24.8815165876777, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=408, Percent_Identity=25.9803921568627, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533556, Length=430, Percent_Identity=25.8139534883721, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=287, Percent_Identity=27.1777003484321, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583789, Length=287, Percent_Identity=25.7839721254355, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24584153, Length=263, Percent_Identity=23.574144486692, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281361682, Length=357, Percent_Identity=21.8487394957983, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641682, Length=267, Percent_Identity=24.3445692883895, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46500; Mature: 46500

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]