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The map label for this gene is soxB [H]

Identifier: 15899380

GI number: 15899380

Start: 2415240

End: 2416775

Strand: Reverse

Name: soxB [H]

Synonym: SSO2657

Alternate gene names: 15899380

Gene position: 2416775-2415240 (Counterclockwise)

Preceding gene: 15899381

Following gene: 15899379

Centisome position: 80.77

GC content: 38.54

Gene sequence:

>1536_bases
ATGAGCCAACTTTTAAATCAGATAAAGGATACTGTTATCCCTAAAAATACGTTAAACGTAGTTTGGCTTTACACTATAGG
TTCTATATTCTGGCTAGGAGTTCTGGGAATAGCAGCCATGAATCTGAGAACGTACTTGACATATAATAGTAATTCCCCCA
ACGTGGGAGAACTATACTACAGTGCATTAACCATTCACGGCTGGGCTGGTATGTTCGGATTTGTACCTTTAGCTGCAGCT
GCTGTTATAGCATTTGCAATGTATAAGAGTAACTTATCTATAGTTCACACTAAGTTAATGGCAATTTTCTTCTGGTTGTC
TAATATCTTCTTAGCGATTGGACTAGCTGGATCACCAGATATGGGTTGGTATATGTACCCTCCATTGGCGATAGAGTCTG
GTAGTAACTTCCACGCTTTTCTATTCTATACTACACCAGCTCTAATGGGGATGGCATATCTATCCTTAACCTTAGCTTTC
ATACTACAGACTGCAATGTTCATAATACTTATTGCAGATGCATATGCAACAAAGCCAAAAAATGAAAGACTAAACATTTT
TGGAGCTTATGGAGTAGCCTTTGCAATAGTTATTGCAATAACGCTTCCCGCTCTTGCTGCATCAACGCTTTGGTACACAC
TGTATTTCTTTGCAGGAGTTCCAGTGAACCCATTACTGTGGGCATTGCTATTTTGGTTCTATGGGCATCCAGTAGTATAT
TACGTTCCATTCCCGTTATTTGGTGCATTATACTACTATATTCCGAAATATGCTGGAAGATCTCTCTTCAGTGAAAAGTG
GGCTAGATGGAATATATACTTGCTATCAATAGGCTCAATGCTTATATGGGTTCACCACCTACAAACATGGCCATTACCAA
TAGACTTGAGAATATGGGTAAACTTATCCACATTAATTTTAGCCTCGGGATCTGGTCTTACCGTATTGAATTTGGGACTC
ACAATACTTCTTTCTCAAAAATATAATTGGAAAGATCCAGTAGGAATGGGAGGACTAATTGCATTAGTAGGATTCATATT
AGCTGGTGTTCAAGCACTCGTTTTACCAGAGAATTCAATAAATCCACTATTCCACAATACCTATTATGTAGTAGGACATT
TCCACTTAATGATATGGACTTTAATAGTAATGGGCTTCACTACAGTATTTTTGGATATGCTAAAAAGCACATTTGGTGGG
TTCAACTTTAGCGAGCAAGCCTCTAAATGGATGAGAATTGGGATGATATGGTGGACTGCACCATTTTTAGGTGTAGGATA
TACGATGTCAGTAATTGGTTATCTAGGAATGCTGAGAAGAATGATAGCGTATCCATCAGTATTTCAACCCTATAACCTAT
TGGAATCAATGCTAGCTGAAATAGGGATTCCGGGACTATTAGTCACAATCTTTGTGGCAATTGTCGATGCATTGGCTTAT
GCTTCTAAACAAGGTATTTTTTCATCTCCTTCTCCCTCAACTTCTCCCTCTAATTTACCCGTAATGGCTAAAGATGGGGT
GAAAAACAATGGGTGA

Upstream 100 bases:

>100_bases
ATTTCGTAACTCCCAATCAGCCAGGGAATTACACATGGTATAATGCGGAATATGATGGCTACTCTTCATCATACATGACT
GGAACTTTGGAGGTGGTATC

Downstream 100 bases:

>100_bases
GGAAAAAAAAGGTATTATAGATACGATAATTGATAGAGTAGGTGTAACTGAAGCGCCATTATTTAAGACACCGGATTACA
TGTATAATATATCCTATTGG

Product: quinol oxidase (SoxABC), cytochrome aa3 subunit (soxB)

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Oxidase aa(3) subunit 1; Quinol oxidase polypeptide I [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSQLLNQIKDTVIPKNTLNVVWLYTIGSIFWLGVLGIAAMNLRTYLTYNSNSPNVGELYYSALTIHGWAGMFGFVPLAAA
AVIAFAMYKSNLSIVHTKLMAIFFWLSNIFLAIGLAGSPDMGWYMYPPLAIESGSNFHAFLFYTTPALMGMAYLSLTLAF
ILQTAMFIILIADAYATKPKNERLNIFGAYGVAFAIVIAITLPALAASTLWYTLYFFAGVPVNPLLWALLFWFYGHPVVY
YVPFPLFGALYYYIPKYAGRSLFSEKWARWNIYLLSIGSMLIWVHHLQTWPLPIDLRIWVNLSTLILASGSGLTVLNLGL
TILLSQKYNWKDPVGMGGLIALVGFILAGVQALVLPENSINPLFHNTYYVVGHFHLMIWTLIVMGFTTVFLDMLKSTFGG
FNFSEQASKWMRIGMIWWTAPFLGVGYTMSVIGYLGMLRRMIAYPSVFQPYNLLESMLAEIGIPGLLVTIFVAIVDALAY
ASKQGIFSSPSPSTSPSNLPVMAKDGVKNNG

Sequences:

>Translated_511_residues
MSQLLNQIKDTVIPKNTLNVVWLYTIGSIFWLGVLGIAAMNLRTYLTYNSNSPNVGELYYSALTIHGWAGMFGFVPLAAA
AVIAFAMYKSNLSIVHTKLMAIFFWLSNIFLAIGLAGSPDMGWYMYPPLAIESGSNFHAFLFYTTPALMGMAYLSLTLAF
ILQTAMFIILIADAYATKPKNERLNIFGAYGVAFAIVIAITLPALAASTLWYTLYFFAGVPVNPLLWALLFWFYGHPVVY
YVPFPLFGALYYYIPKYAGRSLFSEKWARWNIYLLSIGSMLIWVHHLQTWPLPIDLRIWVNLSTLILASGSGLTVLNLGL
TILLSQKYNWKDPVGMGGLIALVGFILAGVQALVLPENSINPLFHNTYYVVGHFHLMIWTLIVMGFTTVFLDMLKSTFGG
FNFSEQASKWMRIGMIWWTAPFLGVGYTMSVIGYLGMLRRMIAYPSVFQPYNLLESMLAEIGIPGLLVTIFVAIVDALAY
ASKQGIFSSPSPSTSPSNLPVMAKDGVKNNG
>Mature_510_residues
SQLLNQIKDTVIPKNTLNVVWLYTIGSIFWLGVLGIAAMNLRTYLTYNSNSPNVGELYYSALTIHGWAGMFGFVPLAAAA
VIAFAMYKSNLSIVHTKLMAIFFWLSNIFLAIGLAGSPDMGWYMYPPLAIESGSNFHAFLFYTTPALMGMAYLSLTLAFI
LQTAMFIILIADAYATKPKNERLNIFGAYGVAFAIVIAITLPALAASTLWYTLYFFAGVPVNPLLWALLFWFYGHPVVYY
VPFPLFGALYYYIPKYAGRSLFSEKWARWNIYLLSIGSMLIWVHHLQTWPLPIDLRIWVNLSTLILASGSGLTVLNLGLT
ILLSQKYNWKDPVGMGGLIALVGFILAGVQALVLPENSINPLFHNTYYVVGHFHLMIWTLIVMGFTTVFLDMLKSTFGGF
NFSEQASKWMRIGMIWWTAPFLGVGYTMSVIGYLGMLRRMIAYPSVFQPYNLLESMLAEIGIPGLLVTIFVAIVDALAYA
SKQGIFSSPSPSTSPSNLPVMAKDGVKNNG

Specific function: Subunit I binds heme a and the bimetallic center [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=275, Percent_Identity=28.3636363636364, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1786634, Length=419, Percent_Identity=23.6276849642005, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6226519, Length=255, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.9.3.-

Molecular weight: Translated: 56810; Mature: 56679

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLLNQIKDTVIPKNTLNVVWLYTIGSIFWLGVLGIAAMNLRTYLTYNSNSPNVGELYY
CHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
SALTIHGWAGMFGFVPLAAAAVIAFAMYKSNLSIVHTKLMAIFFWLSNIFLAIGLAGSPD
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MGWYMYPPLAIESGSNFHAFLFYTTPALMGMAYLSLTLAFILQTAMFIILIADAYATKPK
CCEEECCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NERLNIFGAYGVAFAIVIAITLPALAASTLWYTLYFFAGVPVNPLLWALLFWFYGHPVVY
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEE
YVPFPLFGALYYYIPKYAGRSLFSEKWARWNIYLLSIGSMLIWVHHLQTWPLPIDLRIWV
EECHHHHHHHHHHHHHHHCHHHHHHHHCCEEEEEEEHHHHHHHHHHHHCCCCCEEEEEEE
NLSTLILASGSGLTVLNLGLTILLSQKYNWKDPVGMGGLIALVGFILAGVQALVLPENSI
EEEEEEEECCCCCEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCC
NPLFHNTYYVVGHFHLMIWTLIVMGFTTVFLDMLKSTFGGFNFSEQASKWMRIGMIWWTA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
PFLGVGYTMSVIGYLGMLRRMIAYPSVFQPYNLLESMLAEIGIPGLLVTIFVAIVDALAY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ASKQGIFSSPSPSTSPSNLPVMAKDGVKNNG
HHCCCCCCCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
SQLLNQIKDTVIPKNTLNVVWLYTIGSIFWLGVLGIAAMNLRTYLTYNSNSPNVGELYY
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
SALTIHGWAGMFGFVPLAAAAVIAFAMYKSNLSIVHTKLMAIFFWLSNIFLAIGLAGSPD
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MGWYMYPPLAIESGSNFHAFLFYTTPALMGMAYLSLTLAFILQTAMFIILIADAYATKPK
CCEEECCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NERLNIFGAYGVAFAIVIAITLPALAASTLWYTLYFFAGVPVNPLLWALLFWFYGHPVVY
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEE
YVPFPLFGALYYYIPKYAGRSLFSEKWARWNIYLLSIGSMLIWVHHLQTWPLPIDLRIWV
EECHHHHHHHHHHHHHHHCHHHHHHHHCCEEEEEEEHHHHHHHHHHHHCCCCCEEEEEEE
NLSTLILASGSGLTVLNLGLTILLSQKYNWKDPVGMGGLIALVGFILAGVQALVLPENSI
EEEEEEEECCCCCEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCC
NPLFHNTYYVVGHFHLMIWTLIVMGFTTVFLDMLKSTFGGFNFSEQASKWMRIGMIWWTA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
PFLGVGYTMSVIGYLGMLRRMIAYPSVFQPYNLLESMLAEIGIPGLLVTIFVAIVDALAY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ASKQGIFSSPSPSTSPSNLPVMAKDGVKNNG
HHCCCCCCCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1372250 [H]