Click here to switch to the map view.

The map label for this gene is gdS-2 [H]

Identifier: 15899101

GI number: 15899101

Start: 2140629

End: 2141474

Strand: Direct

Name: gdS-2 [H]

Synonym: SSO2345

Alternate gene names: 15899101

Gene position: 2140629-2141474 (Clockwise)

Preceding gene: 15899100

Following gene: 15899102

Centisome position: 71.54

GC content: 34.04

Gene sequence:

>846_bases
TTGAGTATTATAGAGTTCTGGTTAGAGGCTAAAGCTACTATTGACCGTTTAATAGAGCAGTTTCTAAACTCAAATAGGGA
TTGGGATCTAGTTGATATAAGTAGTTATATTCTTAAAGATGGTAAACGATTTAGGGGAACTTTAAACATGTTCTTCACTG
TCGCTTTAGGAGGAGACATTAAAGATTCTTATGGAGGGGCTTTAGCTATTGAAATTCTCCATTCTGCTTCCTTAGCTTTG
GATGATATAGTTGATCTCGACGCGACTAGGAGAGGTGATAAGGCTGCATGGGTTGTATATGGAAATAGAAAAGTAATTTT
TATAACGAATTATCTTATTCCTACAGCTCTAAGGATAATTCAGACTTCTTATGGTGACGATGCTTTAAATACTAGTATTG
AGTTATGGAAAGACACCTCAGTGGGTGCTCTAAGGGATATGTATGATAATAGTGATTATATACGAACAATTGAATTAAAA
ACCGGTAGTTTATTTAAGCTCTCTACGGTACTATCAGCCTACGCTTCTAAACACTATAATACGAAACAACAGATGCTGGA
TGTAGGCAAGTATTTAGGGATAATCTATCAAGTAATAGACGATTTTGTTGACTATAAAACTAAGAAAGTAGAGGAGATAG
ATGGTAGTGCAAAGCAATTGTTTAAATATTATCGAGAAGGAAAGTTAGAAGAATATGTTAGGTCAGTATATTTAGAATAT
AAGCAAAAATATGATGAGTTAATAAGTAATATTCCCTTCCAATCTAAATATCTTAGTGAGATAAGGTCACTCCCAGAGTT
CTTAGCTAACGGGCTTCTAAAGGAGGCTAACATAGATAAGATTTAA

Upstream 100 bases:

>100_bases
GTTACTGATATTTTGATAGATGCAGACCCGCTATTAGCACCCATATATTTAAGTATGATTATGTTTTACTTAAAAAAGAA
ATAAAGGAGGTTCAGCTAAT

Downstream 100 bases:

>100_bases
GAAATTTAAATTCAAGGTCTTTTTGGTGAATTATTATTAGACTTGCAGTAATCCATGAATCTGAGAAGGTTACTAAGGCT
TCTAAGCAACTTTTACTTGA

Product: geranylgeranyl pyrophosphate synthetase, putative (gdS-2)

Products: NA

Alternate protein names: All-trans-octaprenyl-diphosphate synthase; Octaprenyl pyrophosphate synthase; OPP synthase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSIIEFWLEAKATIDRLIEQFLNSNRDWDLVDISSYILKDGKRFRGTLNMFFTVALGGDIKDSYGGALAIEILHSASLAL
DDIVDLDATRRGDKAAWVVYGNRKVIFITNYLIPTALRIIQTSYGDDALNTSIELWKDTSVGALRDMYDNSDYIRTIELK
TGSLFKLSTVLSAYASKHYNTKQQMLDVGKYLGIIYQVIDDFVDYKTKKVEEIDGSAKQLFKYYREGKLEEYVRSVYLEY
KQKYDELISNIPFQSKYLSEIRSLPEFLANGLLKEANIDKI

Sequences:

>Translated_281_residues
MSIIEFWLEAKATIDRLIEQFLNSNRDWDLVDISSYILKDGKRFRGTLNMFFTVALGGDIKDSYGGALAIEILHSASLAL
DDIVDLDATRRGDKAAWVVYGNRKVIFITNYLIPTALRIIQTSYGDDALNTSIELWKDTSVGALRDMYDNSDYIRTIELK
TGSLFKLSTVLSAYASKHYNTKQQMLDVGKYLGIIYQVIDDFVDYKTKKVEEIDGSAKQLFKYYREGKLEEYVRSVYLEY
KQKYDELISNIPFQSKYLSEIRSLPEFLANGLLKEANIDKI
>Mature_280_residues
SIIEFWLEAKATIDRLIEQFLNSNRDWDLVDISSYILKDGKRFRGTLNMFFTVALGGDIKDSYGGALAIEILHSASLALD
DIVDLDATRRGDKAAWVVYGNRKVIFITNYLIPTALRIIQTSYGDDALNTSIELWKDTSVGALRDMYDNSDYIRTIELKT
GSLFKLSTVLSAYASKHYNTKQQMLDVGKYLGIIYQVIDDFVDYKTKKVEEIDGSAKQLFKYYREGKLEEYVRSVYLEYK
QKYDELISNIPFQSKYLSEIRSLPEFLANGLLKEANIDKI

Specific function: Supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=216, Percent_Identity=27.3148148148148, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325188, Length=210, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.90 [H]

Molecular weight: Translated: 32275; Mature: 32144

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIEFWLEAKATIDRLIEQFLNSNRDWDLVDISSYILKDGKRFRGTLNMFFTVALGGDI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHEEEEEECCCC
KDSYGGALAIEILHSASLALDDIVDLDATRRGDKAAWVVYGNRKVIFITNYLIPTALRII
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECHHHHHHHHHH
QTSYGDDALNTSIELWKDTSVGALRDMYDNSDYIRTIELKTGSLFKLSTVLSAYASKHYN
HHCCCCHHHCCCHHEECCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
TKQQMLDVGKYLGIIYQVIDDFVDYKTKKVEEIDGSAKQLFKYYREGKLEEYVRSVYLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHH
KQKYDELISNIPFQSKYLSEIRSLPEFLANGLLKEANIDKI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SIIEFWLEAKATIDRLIEQFLNSNRDWDLVDISSYILKDGKRFRGTLNMFFTVALGGDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHEEEEEECCCC
KDSYGGALAIEILHSASLALDDIVDLDATRRGDKAAWVVYGNRKVIFITNYLIPTALRII
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECHHHHHHHHHH
QTSYGDDALNTSIELWKDTSVGALRDMYDNSDYIRTIELKTGSLFKLSTVLSAYASKHYN
HHCCCCHHHCCCHHEECCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
TKQQMLDVGKYLGIIYQVIDDFVDYKTKKVEEIDGSAKQLFKYYREGKLEEYVRSVYLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHH
KQKYDELISNIPFQSKYLSEIRSLPEFLANGLLKEANIDKI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]