Click here to switch to the map view.

The map label for this gene is treZ

Identifier: 15898877

GI number: 15898877

Start: 1906943

End: 1908628

Strand: Direct

Name: treZ

Synonym: SSO2093

Alternate gene names: 15898877

Gene position: 1906943-1908628 (Clockwise)

Preceding gene: 15898876

Following gene: 15898878

Centisome position: 63.73

GC content: 36.3

Gene sequence:

>1686_bases
ATGACGTTTGGTTATAAATTAGATGAAGACGGCGTAACCTTTAATTTATGGGCTCCCTATCAAAGGAAAGTTAAGTTAAA
GATATTAAATAGGGGAATTTATGAGATGGAAAGAGATGACAAGGGATACTTTACTATTACTCTAGATAACGTGAGAGTTG
GTGATAGATATAAGTACATTCTAGATGACAACAGTGAAGTACCAGATCCAGCTTCTAGGTATCAGCCCGAGGGAGTTCAC
GGCTATTCTGAAATTATTTCACCAGATTTCGAATGGGATGATGAGAATAGCGTAAAGGTAAAAAGGGAGGATCTCGTAAT
TTATGAACTTCATATAGGTACATTTACATCAGAAGGTACTTTTGAAGGGGTGATAAAGAAGCTAAACTACTTAAAGGAAC
TTGGAGTAACTGCAATAGAGATAATGCCAATTGCACAGTTTCCAGGGAAAAAAGACTGGGGCTATGATGGGGTTTACTTG
TACGCTGTACAGAACTCTTATGGAGGACCAAGTGGATTTAGGAAACTAGTAAATGAGGCCCATAAGCTGGGATTAGCGGT
AATATTAGACGTAGTTTATAATCACGTTGGGCCAGAAGGAAATTATATGGTAAAGTTAGGGCCCTATTTCTCAGAGAAAT
ATAAAACCCCTTGGGGTTTAACATTTAATTTTGACGATGCTGGAAGTGATGAAGTTAGAAAGTTCATACTGGAAAATGTT
GAATATTGGATAAATGAGTTTCACGTTGATGGATTTAGACTTGACGCTGTTCACGCCATTATTGATAATTCTCCAAAACA
TATCTTAGAGGATATTGCTGATGTAGTCCACAAATATGACAAGATTGTAATAGCCGAGAGTGATTTAAATGATCCCAGAG
TTGTTAATCCTAAAGAGAAGTGTGGATATAATATTGATGCCCAGTGGGTAGATGATTTTCATCATGCAATACATGCTTTC
TTGACCGGTGAGAGACAAGGTTATTATAGTGACTTTGGTAGTATAGGTGATATAGTTAAATCGTACAAAGATGTCTTCAT
ATATGATGGGAAGTACTCGAACTTTAGAAGAAAAACTCACGGAAAATCGGTCGGCGATCTAGATGGTTGTAAGTTCGTAG
TTTATATACAAAATCACGATCAAGTTGGCAATAGGGGTGGAGGGGAAAGATTAATTAAACTGGTTGATAAGGAGAGCTAT
AAGATCGCTGCAGCGCTTTACATACTTTCACCATATATTCCAATGATCTTTATGGGAGAGGAATACGGTGAGGAAAATCC
GTTTTACTACTTTTCCGACTTTTCTGATCCTAAACTAATACAAGGAGTTAGAGAGGGTAGAAGAAGAGAGAATGGACAAG
AGACTGATCCACAGTCCGACTGCACATTTAACGATTCTAAGTTAAGCTGGAAGATAAATGACGATATTCTTTCATTTTAC
AAGAGTTTAATAAAAATAAGGAAAGAGTATGGTTTAGCTTGTAATAGAAAATTGAGTGTTGAAAATGGGAATTATTGGTT
AACCGTGAAAGGAAATGGGTGTTTAGCTGTTTACGTGTTTTCCAAATCTGTAATTGAAATGAAATATAGTGGGACTTTAG
TTCTATCCTCCAATAGCTCTTTTCCATCACAAATTACAGAAAGTAAGTACGAATTAGATAAGGGATTTGCTTTATATAAA
CTTTAG

Upstream 100 bases:

>100_bases
CTAAAATAAGCCTAGTCTTCCTACTCATCTCATTGGCAATGATGATACTAGCTGGTTCAATAGCACAAGTTATAACTTAG
ATAAGTGAGGAAACGTATAT

Downstream 100 bases:

>100_bases
GGCAGGAGAGTTTAAAAATTCCTATAAATGATTATACTTTAGATGACAAGTAAAAATAAAATAGATGAGGAAGAGAGAAG
GAGAAGAGAAGAAGTTAAAA

Product: maltooligosyltrehalose trehalohydrolase TreZ

Products: NA

Alternate protein names: MTHase; 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase; Maltooligosyl trehalose trehalohydrolase

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTFGYKLDEDGVTFNLWAPYQRKVKLKILNRGIYEMERDDKGYFTITLDNVRVGDRYKYILDDNSEVPDPASRYQPEGVH
GYSEIISPDFEWDDENSVKVKREDLVIYELHIGTFTSEGTFEGVIKKLNYLKELGVTAIEIMPIAQFPGKKDWGYDGVYL
YAVQNSYGGPSGFRKLVNEAHKLGLAVILDVVYNHVGPEGNYMVKLGPYFSEKYKTPWGLTFNFDDAGSDEVRKFILENV
EYWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYDKIVIAESDLNDPRVVNPKEKCGYNIDAQWVDDFHHAIHAF
LTGERQGYYSDFGSIGDIVKSYKDVFIYDGKYSNFRRKTHGKSVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESY
KIAAALYILSPYIPMIFMGEEYGEENPFYYFSDFSDPKLIQGVREGRRRENGQETDPQSDCTFNDSKLSWKINDDILSFY
KSLIKIRKEYGLACNRKLSVENGNYWLTVKGNGCLAVYVFSKSVIEMKYSGTLVLSSNSSFPSQITESKYELDKGFALYK
L

Sequences:

>Translated_561_residues
MTFGYKLDEDGVTFNLWAPYQRKVKLKILNRGIYEMERDDKGYFTITLDNVRVGDRYKYILDDNSEVPDPASRYQPEGVH
GYSEIISPDFEWDDENSVKVKREDLVIYELHIGTFTSEGTFEGVIKKLNYLKELGVTAIEIMPIAQFPGKKDWGYDGVYL
YAVQNSYGGPSGFRKLVNEAHKLGLAVILDVVYNHVGPEGNYMVKLGPYFSEKYKTPWGLTFNFDDAGSDEVRKFILENV
EYWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYDKIVIAESDLNDPRVVNPKEKCGYNIDAQWVDDFHHAIHAF
LTGERQGYYSDFGSIGDIVKSYKDVFIYDGKYSNFRRKTHGKSVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESY
KIAAALYILSPYIPMIFMGEEYGEENPFYYFSDFSDPKLIQGVREGRRRENGQETDPQSDCTFNDSKLSWKINDDILSFY
KSLIKIRKEYGLACNRKLSVENGNYWLTVKGNGCLAVYVFSKSVIEMKYSGTLVLSSNSSFPSQITESKYELDKGFALYK
L
>Mature_560_residues
TFGYKLDEDGVTFNLWAPYQRKVKLKILNRGIYEMERDDKGYFTITLDNVRVGDRYKYILDDNSEVPDPASRYQPEGVHG
YSEIISPDFEWDDENSVKVKREDLVIYELHIGTFTSEGTFEGVIKKLNYLKELGVTAIEIMPIAQFPGKKDWGYDGVYLY
AVQNSYGGPSGFRKLVNEAHKLGLAVILDVVYNHVGPEGNYMVKLGPYFSEKYKTPWGLTFNFDDAGSDEVRKFILENVE
YWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYDKIVIAESDLNDPRVVNPKEKCGYNIDAQWVDDFHHAIHAFL
TGERQGYYSDFGSIGDIVKSYKDVFIYDGKYSNFRRKTHGKSVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESYK
IAAALYILSPYIPMIFMGEEYGEENPFYYFSDFSDPKLIQGVREGRRRENGQETDPQSDCTFNDSKLSWKINDDILSFYK
SLIKIRKEYGLACNRKLSVENGNYWLTVKGNGCLAVYVFSKSVIEMKYSGTLVLSSNSSFPSQITESKYELDKGFALYKL

Specific function: Hydrolyzes The Alpha-1,6-Glucosidic Linkages In Glycogen Which Has First Been Partially Depolymerized By Phosphorylase. Shows Only Very Little Activity With Native Glycogen. [C]

COG id: COG0296

COG function: function code G; 1,4-alpha-glucan branching enzyme

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family

Homologues:

Organism=Homo sapiens, GI189458812, Length=374, Percent_Identity=25.1336898395722, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI2367229, Length=618, Percent_Identity=22.9773462783171, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789839, Length=291, Percent_Identity=27.8350515463918, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554896, Length=172, Percent_Identity=31.3953488372093, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32564391, Length=177, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320826, Length=298, Percent_Identity=27.1812080536913, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573410, Length=177, Percent_Identity=26.5536723163842, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24586597, Length=87, Percent_Identity=42.5287356321839, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TREZ2_SULSO (P95867)

Other databases:

- EMBL:   Y08256
- EMBL:   AE006641
- PIR:   S73087
- RefSeq:   NP_343482.1
- HSSP:   Q55088
- ProteinModelPortal:   P95867
- SMR:   P95867
- GeneID:   1453599
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO2093
- NMPDR:   fig|273057.1.peg.1905
- HOGENOM:   HBG367595
- OMA:   TPMLFMG
- ProtClustDB:   CLSK285578
- BioCyc:   SSOL273057:SSO2093-MONOMER
- GO:   GO:0005737
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004193
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR015156
- InterPro:   IPR012768
- Gene3D:   G3DSA:2.60.40.1180
- Gene3D:   G3DSA:3.20.20.80
- Gene3D:   G3DSA:2.60.40.10
- PIRSF:   PIRSF006337
- TIGRFAMs:   TIGR02402

Pfam domain/function: PF09071 Alpha-amyl_C; PF00128 Alpha-amylase; PF02922 CBM_48; SSF51445 Glyco_hydro_cat; SSF81296 Ig_E-set

EC number: =3.2.1.141

Molecular weight: Translated: 64371; Mature: 64240

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: ACT_SITE 255-255 ACT_SITE 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFGYKLDEDGVTFNLWAPYQRKVKLKILNRGIYEMERDDKGYFTITLDNVRVGDRYKYI
CCCCCEECCCCEEEEEECCCCCEEEEEEECCCHHHCCCCCCCEEEEEECCEEECCEEEEE
LDDNSEVPDPASRYQPEGVHGYSEIISPDFEWDDENSVKVKREDLVIYELHIGTFTSEGT
ECCCCCCCCHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCEEEEEEEECEECCCCH
FEGVIKKLNYLKELGVTAIEIMPIAQFPGKKDWGYDGVYLYAVQNSYGGPSGFRKLVNEA
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
HKLGLAVILDVVYNHVGPEGNYMVKLGPYFSEKYKTPWGLTFNFDDAGSDEVRKFILENV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
EYWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYDKIVIAESDLNDPRVVNPKEK
HHHHHHHCCCCEEEHEEHHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCEECCCHHH
CGYNIDAQWVDDFHHAIHAFLTGERQGYYSDFGSIGDIVKSYKDVFIYDGKYSNFRRKTH
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHC
GKSVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESYKIAAALYILSPYIPMIFMGE
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEECH
EYGEENPFYYFSDFSDPKLIQGVREGRRRENGQETDPQSDCTFNDSKLSWKINDDILSFY
HHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEECHHHHHHH
KSLIKIRKEYGLACNRKLSVENGNYWLTVKGNGCLAVYVFSKSVIEMKYSGTLVLSSNSS
HHHHHHHHHHCCEECCEEEEECCCEEEEEECCCEEEEEEECCCEEEEEECCEEEEECCCC
FPSQITESKYELDKGFALYKL
CCHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
TFGYKLDEDGVTFNLWAPYQRKVKLKILNRGIYEMERDDKGYFTITLDNVRVGDRYKYI
CCCCEECCCCEEEEEECCCCCEEEEEEECCCHHHCCCCCCCEEEEEECCEEECCEEEEE
LDDNSEVPDPASRYQPEGVHGYSEIISPDFEWDDENSVKVKREDLVIYELHIGTFTSEGT
ECCCCCCCCHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCEEEEEEEECEECCCCH
FEGVIKKLNYLKELGVTAIEIMPIAQFPGKKDWGYDGVYLYAVQNSYGGPSGFRKLVNEA
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
HKLGLAVILDVVYNHVGPEGNYMVKLGPYFSEKYKTPWGLTFNFDDAGSDEVRKFILENV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
EYWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYDKIVIAESDLNDPRVVNPKEK
HHHHHHHCCCCEEEHEEHHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCEECCCHHH
CGYNIDAQWVDDFHHAIHAFLTGERQGYYSDFGSIGDIVKSYKDVFIYDGKYSNFRRKTH
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHC
GKSVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESYKIAAALYILSPYIPMIFMGE
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEECH
EYGEENPFYYFSDFSDPKLIQGVREGRRRENGQETDPQSDCTFNDSKLSWKINDDILSFY
HHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEECHHHHHHH
KSLIKIRKEYGLACNRKLSVENGNYWLTVKGNGCLAVYVFSKSVIEMKYSGTLVLSSNSS
HHHHHHHHHHCCEECCEEEEECCCEEEEEECCCEEEEEEECCCEEEEEECCEEEEECCCC
FPSQITESKYELDKGFALYKL
CCHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726