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The map label for this gene is thpS [H]

Identifier: 15898828

GI number: 15898828

Start: 1850848

End: 1852560

Strand: Direct

Name: thpS [H]

Synonym: SSO2037

Alternate gene names: 15898828

Gene position: 1850848-1852560 (Clockwise)

Preceding gene: 15898827

Following gene: 15898830

Centisome position: 61.85

GC content: 33.63

Gene sequence:

>1713_bases
TTGCAATTTAGGAAAACGTTTTTATTTTTGAACATTCATTTCCCTTACGTGCTAAGGAATACATTACTAATCCTCCTTTT
GCTCTTACCAACACCATTACTGGCCATTTCATTACCAACTGGAGTAGTAGCTTATGACGGTCCTATATTCACAAATCAAG
TATTAGGTTACGTGAATATAACATCACTTCAGGCTTATAATGCATCTGGTTCAAAATTTGGAGTTCCACCTTATGGTGCT
TCGCTGCAATTAAACGTCATGCTACAAGTGAATACTAGCAATGAGGAGTACTATTTTTGGCTACAAAATGTAGCAGATTT
CATTACAAATGAGAGCAAGATGTTCTTTAGTGAAAATATTTGGAACTCAACTACTCCATTAGCTGGAATAAATAACGTAA
TTGGCAAGGGTGAAATATACTCCACCTCAGACCTTTTCTCTCATTCTTCATACTACGCTTACGGCACTTATTATATTAAA
TACGATTTCCCATTTTCGTTTTACCTTATAGTAAATGAAAGCCATAATAATCAAGGAGTATATGTTAGTTTCGGTTACGT
TATTCTTCAGAACGGAAATATAACTCCACCCAATCCAACGTTTTACGATACAGTTTTCATCCCAGTTAATAATTTGACCT
CTGCCTCAATTATAATAGCTAATCAGACTACTCCTAATTTAAACTTAGGTATTATAACATATTTGGGAAGCTACTTAGAT
GCTGAATTGGTATGGGGAGGATTTGGAAATGGTGCATCTACAACGTTCTTAAACATGTCCTCTTATCTAGCATTACTGTA
CATGAAAAACGGTAAATGGGTCCCATTTTCACAAGTATATAATTACGGGAGTGACACAGCAGAGTCCACTAATAATTTAC
GTGTTACCATAGCAAAAAATGGAGATGCATACGTTACAATAGGAAAGCAGAATCCAGGATTGTTAACTACTAACTTTAAC
CCTTCAATCCCTGGTTTCTTATACTTGAATATTAGTAGTAAAATACCGTTTCTAGTTAATAACATCATTTCACGTACTTT
CTCTGGTTACGTTTCAGCCCCAATTAAATTAGGCTTCTTTATGAATTATTCCATTAACTCATCCTCCTTTGCAGTCCTCA
ATGGAAACTATCCTAGCTTAATAGAACCTAACGTCAGTTGGTTCAAGATTTTGAACATTATCCCTAACTACACATATTAC
TACTTGGTGAGAGTAAACTCATCTATTCCAGTTATTGGCACGATAAATGGTAAACAAATTACCTTAAATGATACAAATTG
GTTTGCCCAAGGTACTCAAATCAAAATAGTTAATTACACGTATTATAATGGTAGCGATGAGAGGTATGTTATTTCATCAA
TTTTACCATCGCTATCGTTTAACATTAGCTCGCCTTTAAACGTTACCATAAACACTATAAAACAATATCGAGTTATAATA
AACTCCGATTTGCCAACATACTTAAATGATAAAAGGGTAAATGGAAGCATATGGATTAACACTGGTACAATTGTTAAATT
AAGTGCAAGTATCCCCTTTTATGAAGTGGGAAGGTTTATCGGGACTTATAACTTAACACTAGGAGGGACCATAGTAGTGA
ATAAACCGATAGTTGAAAAATTGCAATTATCTATTAATAATTTACTATTAGAAATAACGGCTATAATAATAGTAATAGTT
ATTATCATGTTAATACTGAGAAAGAGAAGATAA

Upstream 100 bases:

>100_bases
CATAGAGTAGGAAGGACTGGTAGAATGGGAAGAGTGGGTCAAGCAATAACGTTCTATACGTTCAGAGAAGCTGACATGAT
TAAAAGAATCAATAACTTAC

Downstream 100 bases:

>100_bases
AATTATAGCGTGACTTTTTTAAACCTAAGTCTTACGTGAATATAAGCCAAAAATAACCCAACAAGCATTGAGACTATTAT
AAGAACTAATGTATTGAAAT

Product: thermopsin precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MQFRKTFLFLNIHFPYVLRNTLLILLLLLPTPLLAISLPTGVVAYDGPIFTNQVLGYVNITSLQAYNASGSKFGVPPYGA
SLQLNVMLQVNTSNEEYYFWLQNVADFITNESKMFFSENIWNSTTPLAGINNVIGKGEIYSTSDLFSHSSYYAYGTYYIK
YDFPFSFYLIVNESHNNQGVYVSFGYVILQNGNITPPNPTFYDTVFIPVNNLTSASIIIANQTTPNLNLGIITYLGSYLD
AELVWGGFGNGASTTFLNMSSYLALLYMKNGKWVPFSQVYNYGSDTAESTNNLRVTIAKNGDAYVTIGKQNPGLLTTNFN
PSIPGFLYLNISSKIPFLVNNIISRTFSGYVSAPIKLGFFMNYSINSSSFAVLNGNYPSLIEPNVSWFKILNIIPNYTYY
YLVRVNSSIPVIGTINGKQITLNDTNWFAQGTQIKIVNYTYYNGSDERYVISSILPSLSFNISSPLNVTINTIKQYRVII
NSDLPTYLNDKRVNGSIWINTGTIVKLSASIPFYEVGRFIGTYNLTLGGTIVVNKPIVEKLQLSINNLLLEITAIIIVIV
IIMLILRKRR

Sequences:

>Translated_570_residues
MQFRKTFLFLNIHFPYVLRNTLLILLLLLPTPLLAISLPTGVVAYDGPIFTNQVLGYVNITSLQAYNASGSKFGVPPYGA
SLQLNVMLQVNTSNEEYYFWLQNVADFITNESKMFFSENIWNSTTPLAGINNVIGKGEIYSTSDLFSHSSYYAYGTYYIK
YDFPFSFYLIVNESHNNQGVYVSFGYVILQNGNITPPNPTFYDTVFIPVNNLTSASIIIANQTTPNLNLGIITYLGSYLD
AELVWGGFGNGASTTFLNMSSYLALLYMKNGKWVPFSQVYNYGSDTAESTNNLRVTIAKNGDAYVTIGKQNPGLLTTNFN
PSIPGFLYLNISSKIPFLVNNIISRTFSGYVSAPIKLGFFMNYSINSSSFAVLNGNYPSLIEPNVSWFKILNIIPNYTYY
YLVRVNSSIPVIGTINGKQITLNDTNWFAQGTQIKIVNYTYYNGSDERYVISSILPSLSFNISSPLNVTINTIKQYRVII
NSDLPTYLNDKRVNGSIWINTGTIVKLSASIPFYEVGRFIGTYNLTLGGTIVVNKPIVEKLQLSINNLLLEITAIIIVIV
IIMLILRKRR
>Mature_570_residues
MQFRKTFLFLNIHFPYVLRNTLLILLLLLPTPLLAISLPTGVVAYDGPIFTNQVLGYVNITSLQAYNASGSKFGVPPYGA
SLQLNVMLQVNTSNEEYYFWLQNVADFITNESKMFFSENIWNSTTPLAGINNVIGKGEIYSTSDLFSHSSYYAYGTYYIK
YDFPFSFYLIVNESHNNQGVYVSFGYVILQNGNITPPNPTFYDTVFIPVNNLTSASIIIANQTTPNLNLGIITYLGSYLD
AELVWGGFGNGASTTFLNMSSYLALLYMKNGKWVPFSQVYNYGSDTAESTNNLRVTIAKNGDAYVTIGKQNPGLLTTNFN
PSIPGFLYLNISSKIPFLVNNIISRTFSGYVSAPIKLGFFMNYSINSSSFAVLNGNYPSLIEPNVSWFKILNIIPNYTYY
YLVRVNSSIPVIGTINGKQITLNDTNWFAQGTQIKIVNYTYYNGSDERYVISSILPSLSFNISSPLNVTINTIKQYRVII
NSDLPTYLNDKRVNGSIWINTGTIVKLSASIPFYEVGRFIGTYNLTLGGTIVVNKPIVEKLQLSINNLLLEITAIIIVIV
IIMLILRKRR

Specific function: May represent a new class of acid proteases. It digests proteins and peptides in acidic solution [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=May be linked to cells by covalent linkages through some side chains [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A5 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007981 [H]

Pfam domain/function: PF05317 Thermopsin [H]

EC number: =3.4.23.42 [H]

Molecular weight: Translated: 63797; Mature: 63797

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFRKTFLFLNIHFPYVLRNTLLILLLLLPTPLLAISLPTGVVAYDGPIFTNQVLGYVNI
CCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCEECCCEEEEEEE
TSLQAYNASGSKFGVPPYGASLQLNVMLQVNTSNEEYYFWLQNVADFITNESKMFFSENI
EEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEHHHHHHHHCCCCCEEEECCC
WNSTTPLAGINNVIGKGEIYSTSDLFSHSSYYAYGTYYIKYDFPFSFYLIVNESHNNQGV
CCCCCCCCCCHHHCCCCCEEECHHHHCCCCEEEEEEEEEEEECCEEEEEEEECCCCCCEE
YVSFGYVILQNGNITPPNPTFYDTVFIPVNNLTSASIIIANQTTPNLNLGIITYLGSYLD
EEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHCC
AELVWGGFGNGASTTFLNMSSYLALLYMKNGKWVPFSQVYNYGSDTAESTNNLRVTIAKN
EEEEEECCCCCCCEEEEEHHHEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEEEEC
GDAYVTIGKQNPGLLTTNFNPSIPGFLYLNISSKIPFLVNNIISRTFSGYVSAPIKLGFF
CCEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEECCEEEEEE
MNYSINSSSFAVLNGNYPSLIEPNVSWFKILNIIPNYTYYYLVRVNSSIPVIGTINGKQI
EEEEECCCEEEEEECCCCCEECCCCHHEEHHHHCCCCEEEEEEEECCCCCEEEECCCCEE
TLNDTNWFAQGTQIKIVNYTYYNGSDERYVISSILPSLSFNISSPLNVTINTIKQYRVII
EEECCCEEECCCEEEEEEEEEECCCCCEEEHHHHHCCCEECCCCCCEEEEEEEEEEEEEE
NSDLPTYLNDKRVNGSIWINTGTIVKLSASIPFYEVGRFIGTYNLTLGGTIVVNKPIVEK
ECCCCCCCCCCCCCCEEEEECCEEEEEECCCCHHHHHHHHEEEEEEECCEEEECCHHHHH
LQLSINNLLLEITAIIIVIVIIMLILRKRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQFRKTFLFLNIHFPYVLRNTLLILLLLLPTPLLAISLPTGVVAYDGPIFTNQVLGYVNI
CCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCEECCCEEEEEEE
TSLQAYNASGSKFGVPPYGASLQLNVMLQVNTSNEEYYFWLQNVADFITNESKMFFSENI
EEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEHHHHHHHHCCCCCEEEECCC
WNSTTPLAGINNVIGKGEIYSTSDLFSHSSYYAYGTYYIKYDFPFSFYLIVNESHNNQGV
CCCCCCCCCCHHHCCCCCEEECHHHHCCCCEEEEEEEEEEEECCEEEEEEEECCCCCCEE
YVSFGYVILQNGNITPPNPTFYDTVFIPVNNLTSASIIIANQTTPNLNLGIITYLGSYLD
EEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHCC
AELVWGGFGNGASTTFLNMSSYLALLYMKNGKWVPFSQVYNYGSDTAESTNNLRVTIAKN
EEEEEECCCCCCCEEEEEHHHEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEEEEC
GDAYVTIGKQNPGLLTTNFNPSIPGFLYLNISSKIPFLVNNIISRTFSGYVSAPIKLGFF
CCEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEECCEEEEEE
MNYSINSSSFAVLNGNYPSLIEPNVSWFKILNIIPNYTYYYLVRVNSSIPVIGTINGKQI
EEEEECCCEEEEEECCCCCEECCCCHHEEHHHHCCCCEEEEEEEECCCCCEEEECCCCEE
TLNDTNWFAQGTQIKIVNYTYYNGSDERYVISSILPSLSFNISSPLNVTINTIKQYRVII
EEECCCEEECCCEEEEEEEEEECCCCCEEEHHHHHCCCEECCCCCCEEEEEEEEEEEEEE
NSDLPTYLNDKRVNGSIWINTGTIVKLSASIPFYEVGRFIGTYNLTLGGTIVVNKPIVEK
ECCCCCCCCCCCCCCEEEEECCEEEEEECCCCHHHHHHHHEEEEEEECCEEEECCHHHHH
LQLSINNLLLEITAIIIVIVIIMLILRKRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2104843 [H]