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The map label for this gene is dapE [H]

Identifier: 15898364

GI number: 15898364

Start: 1390102

End: 1391334

Strand: Reverse

Name: dapE [H]

Synonym: SSO1538

Alternate gene names: 15898364

Gene position: 1391334-1390102 (Counterclockwise)

Preceding gene: 15898368

Following gene: 15898361

Centisome position: 46.5

GC content: 36.9

Gene sequence:

>1233_bases
ATGTCAAAAATTGATGAGATTATTGAAGAACTAAGAGGGGAGATAGTCGATTTTTTAAAGGAGTTGATAAGAATCCCCAC
TGAGAATCCCCCTGGATTGAATTATGAGAAAATTGTTAATGTTATAAAAAATAAATTGGATGAATTTGGTTATAAAACTC
AAGTAATAGAGCCCACTGATGAAGAGTTGAAAAGTCTGATTAGATTTGGTTATGGTAAAAGACCTAATCTAGTTGGATAT
TTAGGTAATGGTAACAATAGAATAGCCTTTAACGCTCATTACGATGTAGTCCCTGCAGGAGAGGGATGGAGTGTAGATCC
CTATAAAGGAATAGAGAAGGACGGTAAAATTTACGGGAGAGGTGCCTCAGATATGAAGTCTGGTATAGTTGCGCAAATTT
ACGCAATAGAGATGTTAAGGAGAGCTAAACTGTTACCATCAAATATCCAAGTGATTCAAACAATTGTTCCAGATGAGGAA
ACTGTCGGTAATAGGAATGCAGGAACTTATTATTTGGTCCAAAAGGGTATATTTAAGAATGTAAATTACGTCATATTCAC
TGAGCCTACTGGGCCAGATAATGTGTGTAATGGTCATAGGGGTGCAATATGGGCTATTGTAAGGGTTTATGGTAAGAAAA
GTCATGGTGGGTTTCCACAGTTGGGAATCGATGCGGTTAAAGCTACCTCCCTAATGATAGAAGAGCTTTATAAGGCAATT
CCCGATATTGTATCTAAATACGAGATATCTCCAGAGTCGGGTAAAAAGCCTACCATATTAGTTGGCGTGGTTAAATGCGG
AACATGGGTAAATACGGTAGCGGACTATTGTGAATTTAGTATAGTAAGAAGGCTAATCCCAGAGGAAAATTTAGAGGAGG
TGAGACATAGCATAATTAGGGTTTTGGATAACATAAGTAAAAGTACTGGAGTAAGGTACGAATATGACGAATTTTATGCG
GTAAATACTATGCGTTGCGATGATGAGAGATTAATAAGTGCATTGAGGGAAAAGATTAGAGAGGTAAGAGGAGTTGAGGC
TAGAACCGTATTATCAGCAGGGACATTTGATATTAGATTCACTATTAATGAAGGGATAAAAAGTATTAATTACGGTCCAG
GAAGAATTGAGCTAGCTCATGCTAATGATGAGTACATATATGTGAAGGACCTACTGGATTCCATCAAGGTTTTAGGACTA
TTAGTATTAGAACTATCCAATAAGACGAAATAA

Upstream 100 bases:

>100_bases
AAGAACTTTTCCAAAATACTAATGATTAATTATAAATTTCTGTATACTTCTAAAGTTTTGCCCGCAAAACATTATTAAGG
GGAAATTTTTAATTAAATAT

Downstream 100 bases:

>100_bases
ATACTGCAAACGTGTTTGAAGATTTTTAAAAATTAGTAAATTTCTAACTTTATATACTTATCGAATTTTTACAAAGAATT
GAGGGGTATTACAAACACCA

Product: succinyl-diaminopimelate desuccinylase

Products: succinate; LL-2,6-diaminoheptanedioate

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSKIDEIIEELRGEIVDFLKELIRIPTENPPGLNYEKIVNVIKNKLDEFGYKTQVIEPTDEELKSLIRFGYGKRPNLVGY
LGNGNNRIAFNAHYDVVPAGEGWSVDPYKGIEKDGKIYGRGASDMKSGIVAQIYAIEMLRRAKLLPSNIQVIQTIVPDEE
TVGNRNAGTYYLVQKGIFKNVNYVIFTEPTGPDNVCNGHRGAIWAIVRVYGKKSHGGFPQLGIDAVKATSLMIEELYKAI
PDIVSKYEISPESGKKPTILVGVVKCGTWVNTVADYCEFSIVRRLIPEENLEEVRHSIIRVLDNISKSTGVRYEYDEFYA
VNTMRCDDERLISALREKIREVRGVEARTVLSAGTFDIRFTINEGIKSINYGPGRIELAHANDEYIYVKDLLDSIKVLGL
LVLELSNKTK

Sequences:

>Translated_410_residues
MSKIDEIIEELRGEIVDFLKELIRIPTENPPGLNYEKIVNVIKNKLDEFGYKTQVIEPTDEELKSLIRFGYGKRPNLVGY
LGNGNNRIAFNAHYDVVPAGEGWSVDPYKGIEKDGKIYGRGASDMKSGIVAQIYAIEMLRRAKLLPSNIQVIQTIVPDEE
TVGNRNAGTYYLVQKGIFKNVNYVIFTEPTGPDNVCNGHRGAIWAIVRVYGKKSHGGFPQLGIDAVKATSLMIEELYKAI
PDIVSKYEISPESGKKPTILVGVVKCGTWVNTVADYCEFSIVRRLIPEENLEEVRHSIIRVLDNISKSTGVRYEYDEFYA
VNTMRCDDERLISALREKIREVRGVEARTVLSAGTFDIRFTINEGIKSINYGPGRIELAHANDEYIYVKDLLDSIKVLGL
LVLELSNKTK
>Mature_409_residues
SKIDEIIEELRGEIVDFLKELIRIPTENPPGLNYEKIVNVIKNKLDEFGYKTQVIEPTDEELKSLIRFGYGKRPNLVGYL
GNGNNRIAFNAHYDVVPAGEGWSVDPYKGIEKDGKIYGRGASDMKSGIVAQIYAIEMLRRAKLLPSNIQVIQTIVPDEET
VGNRNAGTYYLVQKGIFKNVNYVIFTEPTGPDNVCNGHRGAIWAIVRVYGKKSHGGFPQLGIDAVKATSLMIEELYKAIP
DIVSKYEISPESGKKPTILVGVVKCGTWVNTVADYCEFSIVRRLIPEENLEEVRHSIIRVLDNISKSTGVRYEYDEFYAV
NTMRCDDERLISALREKIREVRGVEARTVLSAGTFDIRFTINEGIKSINYGPGRIELAHANDEYIYVKDLLDSIKVLGLL
VLELSNKTK

Specific function: Unknown

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1789236, Length=418, Percent_Identity=25.8373205741627, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788816, Length=388, Percent_Identity=22.1649484536082, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790395, Length=316, Percent_Identity=25, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982710, Length=409, Percent_Identity=25.1833740831296, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538642, Length=407, Percent_Identity=25.0614250614251, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982082, Length=407, Percent_Identity=23.5872235872236, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538640, Length=402, Percent_Identity=24.1293532338308, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649212, Length=407, Percent_Identity=24.0786240786241, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24649206, Length=405, Percent_Identity=24.1975308641975, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649210, Length=407, Percent_Identity=23.5872235872236, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24649202, Length=406, Percent_Identity=21.9211822660099, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649204, Length=406, Percent_Identity=21.9211822660099, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649208, Length=406, Percent_Identity=21.9211822660099, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.18

Molecular weight: Translated: 46117; Mature: 45985

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIDEIIEELRGEIVDFLKELIRIPTENPPGLNYEKIVNVIKNKLDEFGYKTQVIEPTD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCH
EELKSLIRFGYGKRPNLVGYLGNGNNRIAFNAHYDVVPAGEGWSVDPYKGIEKDGKIYGR
HHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECEEEEECCCCCCCCCCCCCCCCCCEEEC
GASDMKSGIVAQIYAIEMLRRAKLLPSNIQVIQTIVPDEETVGNRNAGTYYLVQKGIFKN
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCHHHCCCCCCCEEEEEECHHHCC
VNYVIFTEPTGPDNVCNGHRGAIWAIVRVYGKKSHGGFPQLGIDAVKATSLMIEELYKAI
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
PDIVSKYEISPESGKKPTILVGVVKCGTWVNTVADYCEFSIVRRLIPEENLEEVRHSIIR
HHHHHHCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VLDNISKSTGVRYEYDEFYAVNTMRCDDERLISALREKIREVRGVEARTVLSAGTFDIRF
HHHHHHHHCCCCEECCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHEEECCCEEEEE
TINEGIKSINYGPGRIELAHANDEYIYVKDLLDSIKVLGLLVLELSNKTK
EEHHCHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKIDEIIEELRGEIVDFLKELIRIPTENPPGLNYEKIVNVIKNKLDEFGYKTQVIEPTD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCH
EELKSLIRFGYGKRPNLVGYLGNGNNRIAFNAHYDVVPAGEGWSVDPYKGIEKDGKIYGR
HHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECEEEEECCCCCCCCCCCCCCCCCCEEEC
GASDMKSGIVAQIYAIEMLRRAKLLPSNIQVIQTIVPDEETVGNRNAGTYYLVQKGIFKN
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCHHHCCCCCCCEEEEEECHHHCC
VNYVIFTEPTGPDNVCNGHRGAIWAIVRVYGKKSHGGFPQLGIDAVKATSLMIEELYKAI
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
PDIVSKYEISPESGKKPTILVGVVKCGTWVNTVADYCEFSIVRRLIPEENLEEVRHSIIR
HHHHHHCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VLDNISKSTGVRYEYDEFYAVNTMRCDDERLISALREKIREVRGVEARTVLSAGTFDIRF
HHHHHHHHCCCCEECCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHEEECCCEEEEE
TINEGIKSINYGPGRIELAHANDEYIYVKDLLDSIKVLGLLVLELSNKTK
EEHHCHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-LL-2,6-diaminoheptanedioate; H2O

Specific reaction: N-succinyl-LL-2,6-diaminoheptanedioate + H2O = succinate + LL-2,6-diaminoheptanedioate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]