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The map label for this gene is 15898360

Identifier: 15898360

GI number: 15898360

Start: 1384983

End: 1386137

Strand: Direct

Name: 15898360

Synonym: SSO1533

Alternate gene names: NA

Gene position: 1384983-1386137 (Clockwise)

Preceding gene: 15898358

Following gene: 15898362

Centisome position: 46.29

GC content: 36.62

Gene sequence:

>1155_bases
ATGGTATTTTATCATAGACAAGGTGAATTGCCTAAGAAGAGGCATACTGTATTCATGAAAGATGGGAAGTTAATGAGGGA
GGAAGTATTTGGGCTTAATGGGTTTAATGGGAGATATTCCCTTCTCTATCATTTAAATCCCCCCACAAGGATAATGAAAT
TAGGGGAGTGGAAAAGTAATACAATAGGGGAGTGGAAGGACGCTGAGTATAGACACCATAAACTCTCAACCTCAAAATTA
AGGAAAAGTAGCGATGTTTTCCTAGATCGTATAGCTCTAATATTTAATGATAATCTCATCATATCCTTTTCAAAAGTAGA
CGAGGGAGATACTAAATTGTTTTACAGAAACGCCGATTTTGATGAGATATATTACGTACACTCAGGGGAAATATTATTTA
AAAGCGTATTTGGGGAAATAGAGGTAAAAGAGGGAGATTATTTAGTAATTCCCAGGGGAACTACTTATACACTCTCCTTT
AAGAAGAACGCAGAGCTTTTTATTATCGAAGGCAAGCAGATAGAAGTGCCTAAAGACTACAGAAATGAATATGGACAATT
AGTTGAGGGCTCCTTCTATTATAATAGAGATCTAAAATTACCTGTTTTAAGAACTTATGACGAAAATGGTAATTACAAGC
TAGTTATCAAAACAGTTAATGGTTTTCAACTGGTAGAGTTAGATACGCATCCTTTTGACGTTGTTGGTTGGGATGGTTAT
CTTTATCCTTTTGCCTTAAGTGTTTACGATTTAGAACCCATTACCGGTAAACTACATCAACCACCAACAGCCTATACTAC
TTTTGCAGCTGACGATTTTGTTGTATGTACGTTTGTGCCTAGATTATTCGATTATCACCCCCAGTCTGTTCCGATATCTT
ATTATCATAATAATATTGATGCTGAAGAGATAATCTTCTATTCCTCTGGACAATTTATGAGTAGAAGAGGAATAAATAAG
GGTGACATAACCCTACATAGGGGAGGCCATATACATGGACCACAGCCAAGTGCAGTTGAGGCAAGCCTTAACAAGAGAGG
TACATATAACGATGAGGTAGCCATTATGGTAGAGACACAGAAAAGAGTGAAAGTGTCTATTTACGCAAAAGAGATAGATG
ATCCAACATATCCATTATCATGGTATACCTCATAG

Upstream 100 bases:

>100_bases
TATATATTCCTAGCTGAATTCCATAAAATAAACTTTACATGGAAACTTTTCCATTATACGCTTAAATATTTCTTTTACCC
TTTTATATTATTGATAGAGT

Downstream 100 bases:

>100_bases
GGACATTTTGTGGAATTCATCAGATAATAATATTTCATTTAGCTTAGATCTATTTTATTGTTTTTAATTTTAATAAGTAA
GAATGTGAAGGGATTTGGGC

Product: homogentisate oxygenase related protein

Products: 4-maleylacetoacetate

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MVFYHRQGELPKKRHTVFMKDGKLMREEVFGLNGFNGRYSLLYHLNPPTRIMKLGEWKSNTIGEWKDAEYRHHKLSTSKL
RKSSDVFLDRIALIFNDNLIISFSKVDEGDTKLFYRNADFDEIYYVHSGEILFKSVFGEIEVKEGDYLVIPRGTTYTLSF
KKNAELFIIEGKQIEVPKDYRNEYGQLVEGSFYYNRDLKLPVLRTYDENGNYKLVIKTVNGFQLVELDTHPFDVVGWDGY
LYPFALSVYDLEPITGKLHQPPTAYTTFAADDFVVCTFVPRLFDYHPQSVPISYYHNNIDAEEIIFYSSGQFMSRRGINK
GDITLHRGGHIHGPQPSAVEASLNKRGTYNDEVAIMVETQKRVKVSIYAKEIDDPTYPLSWYTS

Sequences:

>Translated_384_residues
MVFYHRQGELPKKRHTVFMKDGKLMREEVFGLNGFNGRYSLLYHLNPPTRIMKLGEWKSNTIGEWKDAEYRHHKLSTSKL
RKSSDVFLDRIALIFNDNLIISFSKVDEGDTKLFYRNADFDEIYYVHSGEILFKSVFGEIEVKEGDYLVIPRGTTYTLSF
KKNAELFIIEGKQIEVPKDYRNEYGQLVEGSFYYNRDLKLPVLRTYDENGNYKLVIKTVNGFQLVELDTHPFDVVGWDGY
LYPFALSVYDLEPITGKLHQPPTAYTTFAADDFVVCTFVPRLFDYHPQSVPISYYHNNIDAEEIIFYSSGQFMSRRGINK
GDITLHRGGHIHGPQPSAVEASLNKRGTYNDEVAIMVETQKRVKVSIYAKEIDDPTYPLSWYTS
>Mature_384_residues
MVFYHRQGELPKKRHTVFMKDGKLMREEVFGLNGFNGRYSLLYHLNPPTRIMKLGEWKSNTIGEWKDAEYRHHKLSTSKL
RKSSDVFLDRIALIFNDNLIISFSKVDEGDTKLFYRNADFDEIYYVHSGEILFKSVFGEIEVKEGDYLVIPRGTTYTLSF
KKNAELFIIEGKQIEVPKDYRNEYGQLVEGSFYYNRDLKLPVLRTYDENGNYKLVIKTVNGFQLVELDTHPFDVVGWDGY
LYPFALSVYDLEPITGKLHQPPTAYTTFAADDFVVCTFVPRLFDYHPQSVPISYYHNNIDAEEIIFYSSGQFMSRRGINK
GDITLHRGGHIHGPQPSAVEASLNKRGTYNDEVAIMVETQKRVKVSIYAKEIDDPTYPLSWYTS

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1533_SULSO (Q97Y16)

Other databases:

- EMBL:   AE006641
- PIR:   D90312
- RefSeq:   NP_342965.1
- ProteinModelPortal:   Q97Y16
- GeneID:   1454534
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO1533
- NMPDR:   fig|273057.1.peg.1388
- HOGENOM:   HBG564210
- OMA:   PYCERDL
- ProtClustDB:   CLSK883730
- BioCyc:   SSOL273057:SSO1533-MONOMER
- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR11056

Pfam domain/function: PF04209 HgmA; SSF51182 RmlC_like_cupin

EC number: 1.13.11.5

Molecular weight: Translated: 44562; Mature: 44562

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFYHRQGELPKKRHTVFMKDGKLMREEVFGLNGFNGRYSLLYHLNPPTRIMKLGEWKSN
CEEEECCCCCCHHHCEEEEECCCCHHHHHCCCCCCCCEEEEEEECCCCHHEEEECCCCCC
TIGEWKDAEYRHHKLSTSKLRKSSDVFLDRIALIFNDNLIISFSKVDEGDTKLFYRNADF
CCCCCCCCCHHHHCCCHHHHCCCCHHHHHEEEEEECCCEEEEEECCCCCCCEEEEECCCC
DEIYYVHSGEILFKSVFGEIEVKEGDYLVIPRGTTYTLSFKKNAELFIIEGKQIEVPKDY
CEEEEEECCCEEEEECCCEEEEECCCEEEEECCCEEEEEEECCCEEEEEECCEEECCHHH
RNEYGQLVEGSFYYNRDLKLPVLRTYDENGNYKLVIKTVNGFQLVELDTHPFDVVGWDGY
HHHHHCEECCEEEECCCCCCEEEEEECCCCCEEEEEEEECCEEEEEECCCCCEEEECCCE
LYPFALSVYDLEPITGKLHQPPTAYTTFAADDFVVCTFVPRLFDYHPQSVPISYYHNNID
EEEEEEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHCCCCCCCEEEEEECCCC
AEEIIFYSSGQFMSRRGINKGDITLHRGGHIHGPQPSAVEASLNKRGTYNDEVAIMVETQ
HHHEEEEECCCCHHHCCCCCCCEEEECCCCCCCCCCCCEEHHCCCCCCCCCEEEEEEECC
KRVKVSIYAKEIDDPTYPLSWYTS
CEEEEEEEEEECCCCCCCEEEECC
>Mature Secondary Structure
MVFYHRQGELPKKRHTVFMKDGKLMREEVFGLNGFNGRYSLLYHLNPPTRIMKLGEWKSN
CEEEECCCCCCHHHCEEEEECCCCHHHHHCCCCCCCCEEEEEEECCCCHHEEEECCCCCC
TIGEWKDAEYRHHKLSTSKLRKSSDVFLDRIALIFNDNLIISFSKVDEGDTKLFYRNADF
CCCCCCCCCHHHHCCCHHHHCCCCHHHHHEEEEEECCCEEEEEECCCCCCCEEEEECCCC
DEIYYVHSGEILFKSVFGEIEVKEGDYLVIPRGTTYTLSFKKNAELFIIEGKQIEVPKDY
CEEEEEECCCEEEEECCCEEEEECCCEEEEECCCEEEEEEECCCEEEEEECCEEECCHHH
RNEYGQLVEGSFYYNRDLKLPVLRTYDENGNYKLVIKTVNGFQLVELDTHPFDVVGWDGY
HHHHHCEECCEEEECCCCCCEEEEEECCCCCEEEEEEEECCEEEEEECCCCCEEEECCCE
LYPFALSVYDLEPITGKLHQPPTAYTTFAADDFVVCTFVPRLFDYHPQSVPISYYHNNID
EEEEEEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHCCCCCCCEEEEEECCCC
AEEIIFYSSGQFMSRRGINKGDITLHRGGHIHGPQPSAVEASLNKRGTYNDEVAIMVETQ
HHHEEEEECCCCHHHCCCCCCCEEEECCCCCCCCCCCCEEHHCCCCCCCCCEEEEEEECC
KRVKVSIYAKEIDDPTYPLSWYTS
CEEEEEEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: homogentisate; O2

Specific reaction: homogentisate + O2 = 4-maleylacetoacetate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726