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The map label for this gene is pcnA-2 [H]

Identifier: 15897914

GI number: 15897914

Start: 905678

End: 906418

Strand: Direct

Name: pcnA-2 [H]

Synonym: SSO1047

Alternate gene names: 15897914

Gene position: 905678-906418 (Clockwise)

Preceding gene: 15897913

Following gene: 15897915

Centisome position: 30.27

GC content: 36.44

Gene sequence:

>741_bases
ATGATGAAAGCTAAGGTAATTGACGCTGTCTCATTCTCTTATATATTAAGAACTGTGGGTGACTTCTTGAGTGAAGCCAA
CTTTATTGTTACTAAGGAGGGTATAAGAGTTAGCGGAATTGATCCTTCAAGAGTAGTTTTTCTAGATATATTTCTCCCAT
CGAGTTACTTTGAGGGATTTGAAGTTAGTCAAGAGAAGGAAATAATAGGGTTTAAGTTAGAGGATGTAAATGATATACTA
AAACGTGTTTTAAAGGACGATACGTTAATACTATCCTCGAACGAATCTAAATTAACACTTACTTTTGATGGAGAATTCAC
TAGATCTTTCGAGCTTCCATTAATTCAAGTTGAATCTACACAGCCGCCTTCAGTCAATTTAGAGTTTCCATTTAAGGCTC
AACTACTCACTATAACTTTTGCGGATATAATTGACGAGTTATCTGATTTAGGTGAAGTTTTGAATATACACTCCAAGGAG
AATAAACTTTATTTTGAAGTTATTGGAGACCTCTCCACTGCAAAAGTAGAGTTGTCAACGGATAACGGTACGTTATTAGA
AGCTTCTGGCGCAGATGTCAGTAGCAGTTATGGGATGGAATACGTTGCGAATACAACTAAAATGAGAAGAGCTTCCGATT
CAATGGAATTGTATTTTGGTTCTCAAATTCCTTTGAAGCTTCGATTTAAATTACCGCAGGAAGGCTATGGGGACTTTTAC
ATTGCACCAAGGGCAGACTAA

Upstream 100 bases:

>100_bases
CTGAAATTCAAAGAGTAATAGCTGGTGGTGAGGATTATTTAACTGAAGAGTCTAATCCTAAGTTATAAGCTTTATTAGTC
CTATAGACTAAATTAAATAG

Downstream 100 bases:

>100_bases
TCTAATAAAGAGTTTTTTTAGGAACTACTATTTAAATGCGGAATTGGAATTGCCAAAGGATATGGAATTAAGGGAGTTTG
CTCTCCAACCATTTGGCTCA

Product: proliferating cell nuclear antigen

Products: NA

Alternate protein names: Proliferating cell nuclear antigen homolog C; PCNA C [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDIL
KRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKE
NKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFY
IAPRAD

Sequences:

>Translated_246_residues
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDIL
KRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKE
NKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFY
IAPRAD
>Mature_246_residues
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDIL
KRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKE
NKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFY
IAPRAD

Specific function: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication [H]

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PCNA family [H]

Homologues:

Organism=Homo sapiens, GI33239451, Length=255, Percent_Identity=21.5686274509804, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4505641, Length=255, Percent_Identity=21.5686274509804, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24585303, Length=254, Percent_Identity=24.8031496062992, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17136790, Length=255, Percent_Identity=21.9607843137255, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45552759, Length=255, Percent_Identity=21.9607843137255, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000730
- InterPro:   IPR022649
- InterPro:   IPR022659
- InterPro:   IPR022648 [H]

Pfam domain/function: PF02747 PCNA_C; PF00705 PCNA_N [H]

EC number: NA

Molecular weight: Translated: 27568; Mature: 27568

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01251 PCNA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGF
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCEEEEEEEEECCCCCCCC
EVSQEKEIIGFKLEDVNDILKRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVEST
CCCCCCEEEEEEEHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEEECCEEEEEECC
QPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELST
CCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEC
DNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFY
CCCEEEEECCCCCCCCCCCHHHHCCHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCEE
IAPRAD
EEECCC
>Mature Secondary Structure
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGF
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCEEEEEEEEECCCCCCCC
EVSQEKEIIGFKLEDVNDILKRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVEST
CCCCCCEEEEEEEHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEEECCEEEEEECC
QPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELST
CCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEC
DNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFY
CCCEEEEECCCCCCCCCCCHHHHCCHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCEE
IAPRAD
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]