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The map label for this gene is 15897637

Identifier: 15897637

GI number: 15897637

Start: 626461

End: 627210

Strand: Reverse

Name: 15897637

Synonym: SSO0736

Alternate gene names: NA

Gene position: 627210-626461 (Counterclockwise)

Preceding gene: 15897638

Following gene: 15897636

Centisome position: 20.96

GC content: 36.4

Gene sequence:

>750_bases
ATGAACATGAGTCAGTCCCAGAAAATTGTCTTACAGCCAAGGTCAATAGTAGTTCCTGGTGAGTTATTAGCAGAAGGCGA
ATTTCAGATTCCTTGGTCTCCTTATATACTAAAGATTAACAGCAAATACTACTCCACAGTTGTTGGGCTTTTTGATGTAA
AAGATACTCAATTTGAGGTAATTCCCTTGGAAGGCTCGTTTTATTATCCTAAGATTAATGACATAGTAATAGGTTTAGTG
GAGGACGTTGAGATCTATGGCTGGGTGGTTGATATAAAAGCACCTTATAAGGCTTACTTACCAGCTTCAAATCTTTTAGG
GAGGTCTATTAATGTTGGAGAGGACTTAAGGAGATATTTAGATGTAGGTGACTATGTTATAGCTAGAATTGAAAATTTTG
ATAGGTCAATAGATCCCGTCTTATCCGTTAAAGGCAAGGATCTAGGGCGTGTAAGTAATGGTATAGTCATCGATATAATG
CCAGTTAAAGTCCCACGCGTTATAGGTAAGAATAAAAGTATGTATGAGACCTTAACCTCAAAAAGCGGATGTAGTATTTT
TGTTGCTAACAATGGTAGGATATGGGCTACTTGCCCTTCACGCTTTTCTGAAGAAATTTTAATTGAGGCAATTAGGAAGA
TCGAGAATGAGTCACATATAAAAGGATTAACAGATAGAATAAAACAATTCATTGAGGAAAAATTAGGTGAGAGAAATGCT
TCAAGTGGAGAGACCAAAACTAATTCTTGA

Upstream 100 bases:

>100_bases
TTGCGGAATTGGAAATACCTGCCGGTGCACAGCAAGACGTTATAGATAAGTTAAATAGTCTTACAAAAGGAGAAGTTGAA
GTTAAAGTATTGCAAGTGAG

Downstream 100 bases:

>100_bases
TGATGGAAAGCGAACAGATGGTAGAAAGCCAGATGAATTAAGAAGTATAAAGATAGAATTAGGTGTTCTCAAAAATGCTG
ATGGCTCGGCAATTTTTGAA

Product: exosome complex RNA-binding protein Rrp4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNMSQSQKIVLQPRSIVVPGELLAEGEFQIPWSPYILKINSKYYSTVVGLFDVKDTQFEVIPLEGSFYYPKINDIVIGLV
EDVEIYGWVVDIKAPYKAYLPASNLLGRSINVGEDLRRYLDVGDYVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIM
PVKVPRVIGKNKSMYETLTSKSGCSIFVANNGRIWATCPSRFSEEILIEAIRKIENESHIKGLTDRIKQFIEEKLGERNA
SSGETKTNS

Sequences:

>Translated_249_residues
MNMSQSQKIVLQPRSIVVPGELLAEGEFQIPWSPYILKINSKYYSTVVGLFDVKDTQFEVIPLEGSFYYPKINDIVIGLV
EDVEIYGWVVDIKAPYKAYLPASNLLGRSINVGEDLRRYLDVGDYVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIM
PVKVPRVIGKNKSMYETLTSKSGCSIFVANNGRIWATCPSRFSEEILIEAIRKIENESHIKGLTDRIKQFIEEKLGERNA
SSGETKTNS
>Mature_249_residues
MNMSQSQKIVLQPRSIVVPGELLAEGEFQIPWSPYILKINSKYYSTVVGLFDVKDTQFEVIPLEGSFYYPKINDIVIGLV
EDVEIYGWVVDIKAPYKAYLPASNLLGRSINVGEDLRRYLDVGDYVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIM
PVKVPRVIGKNKSMYETLTSKSGCSIFVANNGRIWATCPSRFSEEILIEAIRKIENESHIKGLTDRIKQFIEEKLGERNA
SSGETKTNS

Specific function: Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential)

COG id: COG1097

COG function: function code J; RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain

Homologues:

Organism=Drosophila melanogaster, GI24762324, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECR1_SULSO (Q9UXC4)

Other databases:

- EMBL:   Y18930
- EMBL:   AE006641
- PIR:   A99222
- RefSeq:   NP_342242.1
- PDB:   2JE6
- PDB:   2JEA
- PDB:   2JEB
- PDB:   3L7Z
- PDBsum:   2JE6
- PDBsum:   2JEA
- PDBsum:   2JEB
- PDBsum:   3L7Z
- ProteinModelPortal:   Q9UXC4
- SMR:   Q9UXC4
- GeneID:   1454999
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0736
- NMPDR:   fig|273057.1.peg.665
- HOGENOM:   HBG392276
- OMA:   GQNGRIW
- ProtClustDB:   PRK04163
- BioCyc:   SSOL273057:SSO0736-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00623
- InterPro:   IPR004087
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00322
- SMART:   SM00316

Pfam domain/function: PF00013 KH_1; PF00575 S1; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 27999; Mature: 27999

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50084 KH_TYPE_1; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMSQSQKIVLQPRSIVVPGELLAEGEFQIPWSPYILKINSKYYSTVVGLFDVKDTQFEV
CCCCCCCEEEECCCCEEECHHHHCCCCEECCCCCEEEEECCCCEEHEEEEEECCCCEEEE
IPLEGSFYYPKINDIVIGLVEDVEIYGWVVDIKAPYKAYLPASNLLGRSINVGEDLRRYL
EEECCCEECCCCCCEEEEEEECEEEEEEEEEECCCCCEECCHHHHCCCCCCCHHHHHHHH
DVGDYVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIMPVKVPRVIGKNKSMYETLTS
CCCHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCEEEEEECCEEHHHHCCCCHHHHHHCC
KSGCSIFVANNGRIWATCPSRFSEEILIEAIRKIENESHIKGLTDRIKQFIEEKLGERNA
CCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
SSGETKTNS
CCCCCCCCC
>Mature Secondary Structure
MNMSQSQKIVLQPRSIVVPGELLAEGEFQIPWSPYILKINSKYYSTVVGLFDVKDTQFEV
CCCCCCCEEEECCCCEEECHHHHCCCCEECCCCCEEEEECCCCEEHEEEEEECCCCEEEE
IPLEGSFYYPKINDIVIGLVEDVEIYGWVVDIKAPYKAYLPASNLLGRSINVGEDLRRYL
EEECCCEECCCCCCEEEEEEECEEEEEEEEEECCCCCEECCHHHHCCCCCCCHHHHHHHH
DVGDYVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIMPVKVPRVIGKNKSMYETLTS
CCCHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCEEEEEECCEEHHHHCCCCHHHHHHCC
KSGCSIFVANNGRIWATCPSRFSEEILIEAIRKIENESHIKGLTDRIKQFIEEKLGERNA
CCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
SSGETKTNS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726