| Definition | Sulfolobus solfataricus P2 chromosome, complete genome. |
|---|---|
| Accession | NC_002754 |
| Length | 2,992,245 |
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The map label for this gene is paaF-2 [C]
Identifier: 15897564
GI number: 15897564
Start: 565312
End: 566070
Strand: Reverse
Name: paaF-2 [C]
Synonym: SSO0654
Alternate gene names: 15897564
Gene position: 566070-565312 (Counterclockwise)
Preceding gene: 15897566
Following gene: 15897562
Centisome position: 18.92
GC content: 36.5
Gene sequence:
>759_bases ATGGAGACAATAGTTACAAAAGAAGAACCCCCAATAGAATGGATAGTATTAAATAGACCAGACAAATTAAATTCAATTAA CTCGATTATGATAAGGGAAATTGGAGATATTTTAAGGCAAATTGTAGACAATGATAAAATTAAGGTTGTTATATTTACGG GTTCTGGAAAGGCCTTTTCAGCTGGAGCTGATATTTCTCAGTTTAAAGATTTAGACCCAGTTAAAGCTTGGGAATTTGCT ATAAAGGGAAGAGAACTAATGGATTATATTGAAAGGTATCCTAAGCCTACCATAGCCATGATAAATGGATATGCGCTAGG TGGAGGTTTAGAGCTAGCATTGAGTTGTGACCTTAGAATTGCTTCCCAAATTGCAGAACTAGGATTACCAGAAATTAATT TGGGAATTTATCCCGGATTCGGCGGTACTCAGAGATTGGTTAGGCTAATTGGAAAAGGGAGAGCGATGGAAATTATCATG TTAGGTGATATAATAAAAGCCGATTATGCGGAGAGAATAGGCCTTGTAAATAGAGTTGTAGAACCTTCATCTCTTGAAAA AGAGGTAAGGGAATTGGCTTTGAAACTTGCCGAAAAGCCACAAATAGCTATAAGATTAATAAAGACTGTAGTAAATTATG GTAACGACGCTCCAATACTGAGTGGTTTAACGTTAGAAAGTTTAGGATGGGGTATCGCATTTGCAACGGAGGAAGAGAAG AAAAGAGTTAATGAGTTCCTTTCAAGGAGGTCTAAATAA
Upstream 100 bases:
>100_bases TTGATATTATTATATCTCTCCTAGTCACATGTACTATTACTACTTAAAGCTTAAAAAGATAAATATTGCGGTGCATCATA TTCTTTGAGGGTTTCTATCA
Downstream 100 bases:
>100_bases ATACTGGCTCGAATCTTTCCTTGAATGCGTGTCTAGATAACTTTCCTCTTATAGGTAACTTATATCCACAGAACTTACAC CTCATATCCTCAGTGAGGTG
Product: enoyl CoA hydratase (paaF-2)
Products: NA
Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues METIVTKEEPPIEWIVLNRPDKLNSINSIMIREIGDILRQIVDNDKIKVVIFTGSGKAFSAGADISQFKDLDPVKAWEFA IKGRELMDYIERYPKPTIAMINGYALGGGLELALSCDLRIASQIAELGLPEINLGIYPGFGGTQRLVRLIGKGRAMEIIM LGDIIKADYAERIGLVNRVVEPSSLEKEVRELALKLAEKPQIAIRLIKTVVNYGNDAPILSGLTLESLGWGIAFATEEEK KRVNEFLSRRSK
Sequences:
>Translated_252_residues METIVTKEEPPIEWIVLNRPDKLNSINSIMIREIGDILRQIVDNDKIKVVIFTGSGKAFSAGADISQFKDLDPVKAWEFA IKGRELMDYIERYPKPTIAMINGYALGGGLELALSCDLRIASQIAELGLPEINLGIYPGFGGTQRLVRLIGKGRAMEIIM LGDIIKADYAERIGLVNRVVEPSSLEKEVRELALKLAEKPQIAIRLIKTVVNYGNDAPILSGLTLESLGWGIAFATEEEK KRVNEFLSRRSK >Mature_252_residues METIVTKEEPPIEWIVLNRPDKLNSINSIMIREIGDILRQIVDNDKIKVVIFTGSGKAFSAGADISQFKDLDPVKAWEFA IKGRELMDYIERYPKPTIAMINGYALGGGLELALSCDLRIASQIAELGLPEINLGIYPGFGGTQRLVRLIGKGRAMEIIM LGDIIKADYAERIGLVNRVVEPSSLEKEVRELALKLAEKPQIAIRLIKTVVNYGNDAPILSGLTLESLGWGIAFATEEEK KRVNEFLSRRSK
Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=236, Percent_Identity=36.0169491525424, Blast_Score=157, Evalue=7e-39, Organism=Homo sapiens, GI68989263, Length=189, Percent_Identity=38.0952380952381, Blast_Score=123, Evalue=1e-28, Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=34.6590909090909, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI70995211, Length=252, Percent_Identity=28.968253968254, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI45643119, Length=256, Percent_Identity=30.859375, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI260275230, Length=256, Percent_Identity=30.859375, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI260274832, Length=256, Percent_Identity=30.859375, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI4502327, Length=239, Percent_Identity=33.0543933054393, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI31542718, Length=189, Percent_Identity=30.1587301587302, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI213417737, Length=217, Percent_Identity=27.6497695852535, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI157694516, Length=217, Percent_Identity=27.6497695852535, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI150378541, Length=245, Percent_Identity=26.1224489795918, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI261878539, Length=103, Percent_Identity=43.6893203883495, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI37594469, Length=210, Percent_Identity=30.952380952381, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI157694520, Length=174, Percent_Identity=29.8850574712644, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI37594471, Length=210, Percent_Identity=30.952380952381, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI25453481, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI51538573, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4757966, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI51538581, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4757968, Length=213, Percent_Identity=26.2910798122066, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI49355787, Length=213, Percent_Identity=26.2910798122066, Blast_Score=69, Evalue=3e-12, Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=34.1269841269841, Blast_Score=152, Evalue=3e-38, Organism=Escherichia coli, GI221142681, Length=206, Percent_Identity=36.4077669902913, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI1788682, Length=194, Percent_Identity=39.1752577319588, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1787660, Length=256, Percent_Identity=32.03125, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI1790281, Length=177, Percent_Identity=36.7231638418079, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1788597, Length=242, Percent_Identity=31.404958677686, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082183, Length=244, Percent_Identity=28.6885245901639, Blast_Score=92, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=36.4035087719298, Blast_Score=155, Evalue=3e-38, Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=35.0806451612903, Blast_Score=149, Evalue=1e-36, Organism=Caenorhabditis elegans, GI25145438, Length=237, Percent_Identity=35.4430379746835, Blast_Score=144, Evalue=4e-35, Organism=Caenorhabditis elegans, GI17536985, Length=241, Percent_Identity=31.5352697095436, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17534483, Length=222, Percent_Identity=30.6306306306306, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17558304, Length=163, Percent_Identity=38.0368098159509, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560910, Length=202, Percent_Identity=32.6732673267327, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI25144276, Length=191, Percent_Identity=37.17277486911, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17508951, Length=191, Percent_Identity=37.17277486911, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17508953, Length=191, Percent_Identity=37.17277486911, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=26.4423076923077, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI25141363, Length=205, Percent_Identity=26.3414634146341, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25144160, Length=187, Percent_Identity=33.1550802139037, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI25144157, Length=187, Percent_Identity=33.1550802139037, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17540306, Length=179, Percent_Identity=31.8435754189944, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17535521, Length=246, Percent_Identity=25.609756097561, Blast_Score=74, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6320241, Length=203, Percent_Identity=26.6009852216749, Blast_Score=86, Evalue=7e-18, Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=37.6984126984127, Blast_Score=173, Evalue=1e-43, Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=37.6984126984127, Blast_Score=173, Evalue=1e-43, Organism=Drosophila melanogaster, GI24653139, Length=244, Percent_Identity=35.2459016393443, Blast_Score=144, Evalue=6e-35, Organism=Drosophila melanogaster, GI24650670, Length=210, Percent_Identity=31.9047619047619, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI19922422, Length=205, Percent_Identity=26.8292682926829, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI21357171, Length=205, Percent_Identity=32.1951219512195, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24654903, Length=238, Percent_Identity=25.6302521008403, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI19921000, Length=207, Percent_Identity=35.7487922705314, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24583077, Length=207, Percent_Identity=35.7487922705314, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24583079, Length=207, Percent_Identity=35.7487922705314, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI19920382, Length=224, Percent_Identity=25.8928571428571, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI28571729, Length=140, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI28571730, Length=140, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=4e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.116 [H]
Molecular weight: Translated: 27981; Mature: 27981
Theoretical pI: Translated: 5.58; Mature: 5.58
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure METIVTKEEPPIEWIVLNRPDKLNSINSIMIREIGDILRQIVDNDKIKVVIFTGSGKAFS CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEE AGADISQFKDLDPVKAWEFAIKGRELMDYIERYPKPTIAMINGYALGGGLELALSCDLRI CCCCHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEEECEEECCCEEEEEECCHHH ASQIAELGLPEINLGIYPGFGGTQRLVRLIGKGRAMEIIMLGDIIKADYAERIGLVNRVV HHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHC EPSSLEKEVRELALKLAEKPQIAIRLIKTVVNYGNDAPILSGLTLESLGWGIAFATEEEK CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCCHHHCCCCEEEECHHHH KRVNEFLSRRSK HHHHHHHHHCCC >Mature Secondary Structure METIVTKEEPPIEWIVLNRPDKLNSINSIMIREIGDILRQIVDNDKIKVVIFTGSGKAFS CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEE AGADISQFKDLDPVKAWEFAIKGRELMDYIERYPKPTIAMINGYALGGGLELALSCDLRI CCCCHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEEECEEECCCEEEEEECCHHH ASQIAELGLPEINLGIYPGFGGTQRLVRLIGKGRAMEIIMLGDIIKADYAERIGLVNRVV HHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHC EPSSLEKEVRELALKLAEKPQIAIRLIKTVVNYGNDAPILSGLTLESLGWGIAFATEEEK CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCCHHHCCCCEEEECHHHH KRVNEFLSRRSK HHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA