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The map label for this gene is trmE [C]

Identifier: 15897540

GI number: 15897540

Start: 541376

End: 542374

Strand: Reverse

Name: trmE [C]

Synonym: SSO0625

Alternate gene names: 15897540

Gene position: 542374-541376 (Counterclockwise)

Preceding gene: 15897541

Following gene: 15897539

Centisome position: 18.13

GC content: 34.03

Gene sequence:

>999_bases
ATGTTAAATCCATTTGAGAAGTTACAGATCCCGCCAAAAGCCAATCAAACTATTGATACCATGCTAAAAAGGCTGCCAAA
GATAGGTGGTACTACAGTTAGGGATAGAGAGATAAGAAGATTAAAGGAATATTATGAGAGAATTAAGAAATACTACGACT
TTGTGGAACAATTCCCTAAAATTGACGAACTACATCCTTTTTATTTAGAGGCAACTAGAATTATGACTGATATTAATAAA
CTGAGGATATGTTTATCAGTTACCAAGAAAACCAGCGTAATATCTATGAAGATATTGAAAAAATACATCAACCAGATAAG
GAAAAGTCCGGAAAATGAATCTAATCGAATAATGCGTCAAGCGTTTGGAAGAGTAAGTTCCGTATTAAGAAAATCCAGTG
AATGTATAGATAGAGTAATAGACGTAGCGAAAGAATTAAAGAAAATCCAAGGTATAGATCCAACATTGCCGACTATCGTA
GTAGCTGGCCCTCCAAACGTAGGCAAATCCACTTTAGTTTCGAAAATCTCTACAGCTAAACCAGAAATTGCCAGTTATCC
CTTTACTACAAAAGAAGTTCATGTAGGTCATGTAATTTTAGACGACTTTCGTATTCAGGTTATTGATACGCCAGGCATTT
TGGATAGGCCAGAAGCTGAGAGAAATAGAATAGAGAGAAAGGCTACTAACGCGATAAGAAACTTAAATGGCATAATCGTA
TTCATGTTTGATTCCTCGATTTCCTCAGTTCTATCTGTAGAAGGTCAAATAGAATTATTTAGGGAGGTGAAATTATTAAA
AAAGATTGTCATACCTGTAATTAATAAGATTGATGAGAAATATGAAGAATATTATAAAAAGATTGTAGATTTTCTTTTAA
GTGAAGGAAACGAATGGCACGAAATAAGCGCTGAAAAGGGAATCGGTATAGATAAGTTAAAAGAGGAACTTTTTAACTTG
GTAAAAAGTAGTGGTACAAATGAAGTATCGCGTGATTGA

Upstream 100 bases:

>100_bases
AAGGTATGTTATTGGCCGCTGGATGTAAAGAGGATGAAGCGAAAGGAATAAAACCCAGAATACTAACTGTAGACGGAGAA
GTTCCTCCAGGAACTAAGAT

Downstream 100 bases:

>100_bases
AATCTTTACCTCTATCCAAGGTGAAGGGGAGGTTATCGGGATCCCTTCAAATTTCATTAGACTTGCTACGTGCAACTTAA
GATGTGTATGGTGTGATACG

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLNPFEKLQIPPKANQTIDTMLKRLPKIGGTTVRDREIRRLKEYYERIKKYYDFVEQFPKIDELHPFYLEATRIMTDINK
LRICLSVTKKTSVISMKILKKYINQIRKSPENESNRIMRQAFGRVSSVLRKSSECIDRVIDVAKELKKIQGIDPTLPTIV
VAGPPNVGKSTLVSKISTAKPEIASYPFTTKEVHVGHVILDDFRIQVIDTPGILDRPEAERNRIERKATNAIRNLNGIIV
FMFDSSISSVLSVEGQIELFREVKLLKKIVIPVINKIDEKYEEYYKKIVDFLLSEGNEWHEISAEKGIGIDKLKEELFNL
VKSSGTNEVSRD

Sequences:

>Translated_332_residues
MLNPFEKLQIPPKANQTIDTMLKRLPKIGGTTVRDREIRRLKEYYERIKKYYDFVEQFPKIDELHPFYLEATRIMTDINK
LRICLSVTKKTSVISMKILKKYINQIRKSPENESNRIMRQAFGRVSSVLRKSSECIDRVIDVAKELKKIQGIDPTLPTIV
VAGPPNVGKSTLVSKISTAKPEIASYPFTTKEVHVGHVILDDFRIQVIDTPGILDRPEAERNRIERKATNAIRNLNGIIV
FMFDSSISSVLSVEGQIELFREVKLLKKIVIPVINKIDEKYEEYYKKIVDFLLSEGNEWHEISAEKGIGIDKLKEELFNL
VKSSGTNEVSRD
>Mature_332_residues
MLNPFEKLQIPPKANQTIDTMLKRLPKIGGTTVRDREIRRLKEYYERIKKYYDFVEQFPKIDELHPFYLEATRIMTDINK
LRICLSVTKKTSVISMKILKKYINQIRKSPENESNRIMRQAFGRVSSVLRKSSECIDRVIDVAKELKKIQGIDPTLPTIV
VAGPPNVGKSTLVSKISTAKPEIASYPFTTKEVHVGHVILDDFRIQVIDTPGILDRPEAERNRIERKATNAIRNLNGIIV
FMFDSSISSVLSVEGQIELFREVKLLKKIVIPVINKIDEKYEEYYKKIVDFLLSEGNEWHEISAEKGIGIDKLKEELFNL
VKSSGTNEVSRD

Specific function: Exhibits A Very High Intrinsic Gtpase Hydrolysis Rate. Involved In The Biosynthesis Of The Hypermodified Nucleoside 5- Methylaminomethyl-2-Thiouridine, Which Is Found In The Wobble Position Of Some Trnas. [C]

COG id: COG1084

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasmic; may also be associated with the inner membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP1/OBG family. NOG subfamily [H]

Homologues:

Organism=Homo sapiens, GI55953087, Length=329, Percent_Identity=30.6990881458967, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25145602, Length=287, Percent_Identity=31.0104529616725, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI25145600, Length=287, Percent_Identity=31.0104529616725, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6325164, Length=278, Percent_Identity=29.8561151079137, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19921908, Length=287, Percent_Identity=32.404181184669, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006073
- InterPro:   IPR010674
- InterPro:   IPR005225 [H]

Pfam domain/function: PF06858 NOG1 [H]

EC number: NA

Molecular weight: Translated: 38194; Mature: 38194

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPFEKLQIPPKANQTIDTMLKRLPKIGGTTVRDREIRRLKEYYERIKKYYDFVEQFPK
CCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDELHPFYLEATRIMTDINKLRICLSVTKKTSVISMKILKKYINQIRKSPENESNRIMRQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AFGRVSSVLRKSSECIDRVIDVAKELKKIQGIDPTLPTIVVAGPPNVGKSTLVSKISTAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
PEIASYPFTTKEVHVGHVILDDFRIQVIDTPGILDRPEAERNRIERKATNAIRNLNGIIV
CCHHCCCCCCCCEEECEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
FMFDSSISSVLSVEGQIELFREVKLLKKIVIPVINKIDEKYEEYYKKIVDFLLSEGNEWH
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EISAEKGIGIDKLKEELFNLVKSSGTNEVSRD
HCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLNPFEKLQIPPKANQTIDTMLKRLPKIGGTTVRDREIRRLKEYYERIKKYYDFVEQFPK
CCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDELHPFYLEATRIMTDINKLRICLSVTKKTSVISMKILKKYINQIRKSPENESNRIMRQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AFGRVSSVLRKSSECIDRVIDVAKELKKIQGIDPTLPTIVVAGPPNVGKSTLVSKISTAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
PEIASYPFTTKEVHVGHVILDDFRIQVIDTPGILDRPEAERNRIERKATNAIRNLNGIIV
CCHHCCCCCCCCEEECEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
FMFDSSISSVLSVEGQIELFREVKLLKKIVIPVINKIDEKYEEYYKKIVDFLLSEGNEWH
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EISAEKGIGIDKLKEELFNLVKSSGTNEVSRD
HCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]