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The map label for this gene is hmuV [H]

Identifier: 15897413

GI number: 15897413

Start: 419671

End: 420330

Strand: Direct

Name: hmuV [H]

Synonym: SSO0487

Alternate gene names: 15897413

Gene position: 419671-420330 (Clockwise)

Preceding gene: 15897412

Following gene: 15897415

Centisome position: 14.03

GC content: 33.03

Gene sequence:

>660_bases
ATGTTAACGTTGAGGAATATTAGTGTAAGATTAGGAGGCAAATTAATTTTGTCAAGCATTTCTTTTAGTGCAGTAAAAGG
TATTAATGTGATTTTAGGACCAAATGGAAGTGGTAAGACTACGCTACTAAGAGCGATAATTGGGATGATAAAGTATGATG
GTGAAATAAGAGTCGATGGTGAAATATCATACGTTCCAGCTGAGTTTTTCTCTCCTAGTATGAAAGTTCTAGATGTATTA
AAAGCAGGTAGAAAAAGGGCTAATTATGAATCATATATAAAGGAGTTAAATGTGGAGAAGTTTCTTGAGAGAGATTTCTC
CACCTTAAGCTCTGGTGAAAGAAAACTAATCTTAGTAACAAAGGCTCTAGCTGAGGGAGACAATGTAATAATGGATGAAC
CTCTTTCAAATCTTGACGTTAAAAATAAATTCTTTGTGATGAATATTTTAAAGAAGTTTAACCATAAGACCTTTCTGATT
ACTTCTCATGAGCTAGAAACTTTAAGGTATGCTGATAAAGCTATCGTGATCAATAAAGGAAAATTGGAATATGATGGAGG
AGTTAGCGATCTTTCTGACGATCTACTTTCCAACGTATATGGTATAAAGTTCAAAAAAATACAAGTTGACGGTAAAACAT
TCTTTAATGTTACGGGATAA

Upstream 100 bases:

>100_bases
AACATTTTATCTCATGGTATATTTGGTTATTTTATTCCTCTAACTGCGCTTCTTTCAATCATGGGAGCTCCAATAATGAT
ATTCGCGTTGGTGAGAAAAG

Downstream 100 bases:

>100_bases
TAAGCGTTTAAAGGGAGGCAGAGTAATTTGTATTTGTAGTTAAAGCTTATGTTTCGATTAGATCACGATGTAGTTAAGTT
TTCATTAGGTTGCAAATTTT

Product: Iron (III) ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MLTLRNISVRLGGKLILSSISFSAVKGINVILGPNGSGKTTLLRAIIGMIKYDGEIRVDGEISYVPAEFFSPSMKVLDVL
KAGRKRANYESYIKELNVEKFLERDFSTLSSGERKLILVTKALAEGDNVIMDEPLSNLDVKNKFFVMNILKKFNHKTFLI
TSHELETLRYADKAIVINKGKLEYDGGVSDLSDDLLSNVYGIKFKKIQVDGKTFFNVTG

Sequences:

>Translated_219_residues
MLTLRNISVRLGGKLILSSISFSAVKGINVILGPNGSGKTTLLRAIIGMIKYDGEIRVDGEISYVPAEFFSPSMKVLDVL
KAGRKRANYESYIKELNVEKFLERDFSTLSSGERKLILVTKALAEGDNVIMDEPLSNLDVKNKFFVMNILKKFNHKTFLI
TSHELETLRYADKAIVINKGKLEYDGGVSDLSDDLLSNVYGIKFKKIQVDGKTFFNVTG
>Mature_219_residues
MLTLRNISVRLGGKLILSSISFSAVKGINVILGPNGSGKTTLLRAIIGMIKYDGEIRVDGEISYVPAEFFSPSMKVLDVL
KAGRKRANYESYIKELNVEKFLERDFSTLSSGERKLILVTKALAEGDNVIMDEPLSNLDVKNKFFVMNILKKFNHKTFLI
TSHELETLRYADKAIVINKGKLEYDGGVSDLSDDLLSNVYGIKFKKIQVDGKTFFNVTG

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI157502201, Length=193, Percent_Identity=25.9067357512953, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI157502203, Length=193, Percent_Identity=25.9067357512953, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI90421313, Length=201, Percent_Identity=28.3582089552239, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=29.3577981651376, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788002, Length=215, Percent_Identity=25.1162790697674, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367384, Length=206, Percent_Identity=28.1553398058252, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=26.8518518518519, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=241, Percent_Identity=26.9709543568465, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24585557, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552437, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62484234, Length=184, Percent_Identity=26.6304347826087, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24648279, Length=229, Percent_Identity=24.0174672489083, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078426, Length=229, Percent_Identity=24.0174672489083, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585091, Length=182, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28574259, Length=194, Percent_Identity=25.7731958762887, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015863
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 24408; Mature: 24408

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLRNISVRLGGKLILSSISFSAVKGINVILGPNGSGKTTLLRAIIGMIKYDGEIRVDG
CEEEEEEEEEECCEEEEEHHCHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEECC
EISYVPAEFFSPSMKVLDVLKAGRKRANYESYIKELNVEKFLERDFSTLSSGERKLILVT
EEEEECHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEE
KALAEGDNVIMDEPLSNLDVKNKFFVMNILKKFNHKTFLITSHELETLRYADKAIVINKG
EEHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHCCEEEEEECC
KLEYDGGVSDLSDDLLSNVYGIKFKKIQVDGKTFFNVTG
CEEECCCHHHHHHHHHHHHHCCEEEEEEECCCEEEEECC
>Mature Secondary Structure
MLTLRNISVRLGGKLILSSISFSAVKGINVILGPNGSGKTTLLRAIIGMIKYDGEIRVDG
CEEEEEEEEEECCEEEEEHHCHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEECC
EISYVPAEFFSPSMKVLDVLKAGRKRANYESYIKELNVEKFLERDFSTLSSGERKLILVT
EEEEECHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEE
KALAEGDNVIMDEPLSNLDVKNKFFVMNILKKFNHKTFLITSHELETLRYADKAIVINKG
EEHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHCCEEEEEECC
KLEYDGGVSDLSDDLLSNVYGIKFKKIQVDGKTFFNVTG
CEEECCCHHHHHHHHHHHHHCCEEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA