Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 15897363

GI number: 15897363

Start: 376608

End: 377348

Strand: Reverse

Name: gcp [H]

Synonym: SSO0434

Alternate gene names: 15897363

Gene position: 377348-376608 (Counterclockwise)

Preceding gene: 15897364

Following gene: 15897362

Centisome position: 12.61

GC content: 36.84

Gene sequence:

>741_bases
TTGAGAGTTGGAGCTACACTAGCGAGAGCAATAGCATTGAAATATAATAAGAAACTAGTGCCAGTAAACCATGGTATAGG
ACATATTGAAATAGGGTATTTAACAACTGAAGCCAGAGATCCTCTAATCTTATACCTCTCAGGTGGAAATACGATAATAA
CCACTTTCTATAAAGGAAGATTTAGGGTTTTTGGGGAGACATTAGATATTGCATTAGGAAACATGATGGATGTATTTGTA
AGAGAGGTGAGCTTGGCACCACCGTATATTATAAATGGAATACATGTAATTGATATTTGTGCAGAGAAGGGAAATAAATT
GCTTAAATTACCTTACGTTGTTAAAGGTCAAGATATGTCATTTTCCGGATTACTTACAGCAGCTTTAAGGGTTGTTGGCA
AGGAAAAGTTAGAAGATATTTGTTACTCAGTAAGGGAAATAGCATTTGACATGTTGTTAGAGGCTACGGAAAGGGCATTA
GCGCTTACCTCAAAGAAGGAATTAATGATAGTTGGAGGAGTAGCAGCAAGTGTGAGTTTGAGAAAAAAATTAGAAGAGTT
AGGAAAAGAGTGGAATGTACAAATCAAAATAGTACCTCCAGAATTTGCGGGAGACAACGGAGCGATGATAGCCTATGCCG
GTATGTTAGCTGCATCTAAAGGTGTATTTATTGACGTTGATAAATCATACATAAGGCCTAGATGGAGAGTAGATGAGGTT
GATATTCCTTGGAGAAATTAA

Upstream 100 bases:

>100_bases
CTCAGCTACTATATTAAGAAGAGCCTTAGAGAAGGCTAAAATTAGTATAAACGATATTAATTATATAGCGGTAGCTTTAG
GGCCAGGTATAGGACCAGCA

Downstream 100 bases:

>100_bases
GGTTAATTAAGCGTGGCGCAGAATCCAACATATATGAAGGGTATTTTTTAGGCATACATGCAATATTTAAGCAAAGGATC
AAGAAAAGTTATAGAAATCC

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGRFRVFGETLDIALGNMMDVFV
REVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMSFSGLLTAALRVVGKEKLEDICYSVREIAFDMLLEATERAL
ALTSKKELMIVGGVAASVSLRKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEV
DIPWRN

Sequences:

>Translated_246_residues
MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGRFRVFGETLDIALGNMMDVFV
REVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMSFSGLLTAALRVVGKEKLEDICYSVREIAFDMLLEATERAL
ALTSKKELMIVGGVAASVSLRKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEV
DIPWRN
>Mature_246_residues
MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGRFRVFGETLDIALGNMMDVFV
REVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMSFSGLLTAALRVVGKEKLEDICYSVREIAFDMLLEATERAL
ALTSKKELMIVGGVAASVSLRKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEV
DIPWRN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI8923380, Length=250, Percent_Identity=42.8, Blast_Score=193, Evalue=9e-50,
Organism=Homo sapiens, GI116812636, Length=272, Percent_Identity=26.8382352941176, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1789445, Length=249, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71995670, Length=252, Percent_Identity=42.8571428571429, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6322891, Length=265, Percent_Identity=37.7358490566038, Blast_Score=172, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320099, Length=276, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357207, Length=265, Percent_Identity=39.622641509434, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022449
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 27244; Mature: 27244

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGR
CCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCEEEEEEECCE
FRVFGETLDIALGNMMDVFVREVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMS
EEEECHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEEEEECCCCEEEECCEEEECCCCC
FSGLLTAALRVVGKEKLEDICYSVREIAFDMLLEATERALALTSKKELMIVGGVAASVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECHHHHHHH
RKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEV
HHHHHHHCHHCCEEEEEECCCCCCCCCCEEEEEHHHHCCCCEEEEECHHHCCCCCEECCC
DIPWRN
CCCCCC
>Mature Secondary Structure
MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGR
CCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCEEEEEEECCE
FRVFGETLDIALGNMMDVFVREVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMS
EEEECHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEEEEECCCCEEEECCEEEECCCCC
FSGLLTAALRVVGKEKLEDICYSVREIAFDMLLEATERALALTSKKELMIVGGVAASVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECHHHHHHH
RKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEV
HHHHHHHCHHCCEEEEEECCCCCCCCCCEEEEEHHHHCCCCEEEEECHHHCCCCCEECCC
DIPWRN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA