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The map label for this gene is yggV [C]

Identifier: 15897361

GI number: 15897361

Start: 375411

End: 375989

Strand: Reverse

Name: yggV [C]

Synonym: SSO0432

Alternate gene names: 15897361

Gene position: 375989-375411 (Counterclockwise)

Preceding gene: 15897362

Following gene: 15897354

Centisome position: 12.57

GC content: 33.16

Gene sequence:

>579_bases
ATGTTGAGGAGAGGCGTAAAAATAGGAGTATTAACGAATAATGAAAATAAATTTATAGAGCTGAAGGAAATTGCAAAGAA
TTTTAATATAGAGTTAGAGCATCTGAGAGGAGAGAAAATAGAAATACAAAGTGATGACTTAGAAGAAATATCTAGAACTG
CAGCAAATTTGGCATATTTGATATTTAGGAGGCCATTAATAGTAGATGATAGCGGATTATTCGTGCAAGCATTACAGAAT
TTCCCTGGTCCCTATACTAATTTTGTTAAGAATACAATAGGGCTTAAAGGTATACTAAAATTGCTCGAAGGAATAAAAGA
TAGGTCTGCCTATTTTATGACTGCACTAACGTTTACTGACGGAAAAATAATTAAAACATTTATTGGGATCGTAAAGGGAG
CTATTTCTGAAGAGATTAGAGGTAATTTAGGTTTCGGATTTGACCCTATATTTATACCTGAAGGAGAAAAGAGAACTTTC
GCAGAGATGTCATTAGAGGAGAAAAATAGGTACTCTCATAGGGCAAGGGCTTTTGCTAAATTTGCAGAATTCTTAGAGAG
TTATACTGAAAAAGAATAA

Upstream 100 bases:

>100_bases
ATAATATACGATGCATTTATAGAGGGTTACAGAAAAATCATGGGAAGAAAGACTGATGAGATATTAGAACTAGTAAAGGA
TATTAGGATGAGAGGTAGAT

Downstream 100 bases:

>100_bases
ATATATAAGTAGTAATTAATAAAATAACCTACTTATACCTTAAAGTTTCTTTTATACTATCCTCATTTAGATCTTCATAA
TATTTCCTATAGTATTCTCC

Product: HAM1 protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLRRGVKIGVLTNNENKFIELKEIAKNFNIELEHLRGEKIEIQSDDLEEISRTAANLAYLIFRRPLIVDDSGLFVQALQN
FPGPYTNFVKNTIGLKGILKLLEGIKDRSAYFMTALTFTDGKIIKTFIGIVKGAISEEIRGNLGFGFDPIFIPEGEKRTF
AEMSLEEKNRYSHRARAFAKFAEFLESYTEKE

Sequences:

>Translated_192_residues
MLRRGVKIGVLTNNENKFIELKEIAKNFNIELEHLRGEKIEIQSDDLEEISRTAANLAYLIFRRPLIVDDSGLFVQALQN
FPGPYTNFVKNTIGLKGILKLLEGIKDRSAYFMTALTFTDGKIIKTFIGIVKGAISEEIRGNLGFGFDPIFIPEGEKRTF
AEMSLEEKNRYSHRARAFAKFAEFLESYTEKE
>Mature_192_residues
MLRRGVKIGVLTNNENKFIELKEIAKNFNIELEHLRGEKIEIQSDDLEEISRTAANLAYLIFRRPLIVDDSGLFVQALQN
FPGPYTNFVKNTIGLKGILKLLEGIKDRSAYFMTALTFTDGKIIKTFIGIVKGAISEEIRGNLGFGFDPIFIPEGEKRTF
AEMSLEEKNRYSHRARAFAKFAEFLESYTEKE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=194, Percent_Identity=31.9587628865979, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI31657144, Length=162, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1789324, Length=189, Percent_Identity=31.7460317460317, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17556833, Length=188, Percent_Identity=32.9787234042553, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322529, Length=189, Percent_Identity=33.8624338624339, Blast_Score=88, Evalue=9e-19,
Organism=Drosophila melanogaster, GI19920712, Length=159, Percent_Identity=33.9622641509434, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21920; Mature: 21920

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRGVKIGVLTNNENKFIELKEIAKNFNIELEHLRGEKIEIQSDDLEEISRTAANLAYL
CCCCCEEEEEEECCCCCEEEHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHH
IFRRPLIVDDSGLFVQALQNFPGPYTNFVKNTIGLKGILKLLEGIKDRSAYFMTALTFTD
HHHCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC
GKIIKTFIGIVKGAISEEIRGNLGFGFDPIFIPEGEKRTFAEMSLEEKNRYSHRARAFAK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FAEFLESYTEKE
HHHHHHHHHCCC
>Mature Secondary Structure
MLRRGVKIGVLTNNENKFIELKEIAKNFNIELEHLRGEKIEIQSDDLEEISRTAANLAYL
CCCCCEEEEEEECCCCCEEEHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHH
IFRRPLIVDDSGLFVQALQNFPGPYTNFVKNTIGLKGILKLLEGIKDRSAYFMTALTFTD
HHHCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC
GKIIKTFIGIVKGAISEEIRGNLGFGFDPIFIPEGEKRTFAEMSLEEKNRYSHRARAFAK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FAEFLESYTEKE
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA