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The map label for this gene is glmU [H]

Identifier: 15897314

GI number: 15897314

Start: 323985

End: 325076

Strand: Reverse

Name: glmU [H]

Synonym: SSO0381

Alternate gene names: 15897314

Gene position: 325076-323985 (Counterclockwise)

Preceding gene: 15897315

Following gene: 15897312

Centisome position: 10.86

GC content: 37.0

Gene sequence:

>1092_bases
TTGAGTGAAATGAAGGCTATAGTATTAGCTGGAGGAAAGGGAGAGGGACTGTTACCATATACTGAGAAGGTACAGAAAGA
AGCTATTACAGTACTAGGTAAGGCAATAATAAACTACACAATAGAGGGTTTAAAGAAAGCTGGTGTAAAAGAATTTGAAA
TAATTGTAAACGAGAAGGGAAATCAAATAGAAGAAGAGGTGGAGAAACTTGACGTGTCCTTTGAGACCATAGTGCAAAAG
AAACAAGGAATTGATGGAGCAGTTCTAGAAGGTATAGAAAGTATTGATGATGACGTATTTGTATTGGCATTTGGTGATAT
AATAGCGCCTGCGGAATTCTACAAGAGCCTTATGGACACATACATAATGACGGGGAGTCAAGCGGTAATACCGCTGATAC
CGATAAGTGAGGGAACAGAAACTTACGGTTTAGTTAAAATCGTCGATAATAAACTAAAGGTAGTTAAAGAAAGCTCAACT
CTAGCGTTAGGTGGAGCCTACATACTACCAAAACCAAAGGACAATTTCACCTCTCTACTAGATTATATTGATCTACTTTC
TAGTCAAGCTAGACTCAACTATTTCATTTGGTCAGAGAGTTGGGTTGACATAGGTTACCCAGAGGATTTATTATTTGCAT
TGGAAACGTTGCTAAGGAGAAAAGAAAGCGTAATTTCAGATAAGGCTGAGATTTCGAAAAACGCAATAATAGGGAAAGGA
GTTATAATAGAAGATTATGCAATAATAGAAGATTATGCAATAATTAAAGGACCAGCTTATATTGGTAAAAACGCTTACGT
AGGATCATTTTCTCTAGTTAGAGATTATTCCTCCATAGAGGAGGGAGCTAAGATAGGAGCTTACTGTGAAATTGCCCATT
CTTTAATTGAACCCTTTGCTGAAGTAGGTTCAAAATCCTATTTGACTTACTCAATAGTAGGTAAAGGAGCTAAGATAGGA
GCTTCTGTCATAACTGCAAGTTACCCAGCACATTCACTAAGTAGACCTAGATTCAATAAACTTGGCGCTTTAATTTCACC
AGAAAAAGTAATTAAACATGGAAGCGTAATAGAGGCTGGTACGAAGGTTTAA

Upstream 100 bases:

>100_bases
CTTGCCATAGCGCCAATAATTCAACTTATTGCGTATTATGCTTCTGTTAAGAGAGGATATGATCCAGATAAGCCTAGGAA
CCTAGCGAAAACAGTAACGG

Downstream 100 bases:

>100_bases
TAAAAAAAGCCTATATTCCCTTTGCATTTTCTTTTACTCTATCTTCTTCTTAAAAGTACTACAGCGACAATCACTATTAT
TATCACCACTATTGCAATGC

Product: sugar phosphate nucleotydyl transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSEMKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKGNQIEEEVEKLDVSFETIVQK
KQGIDGAVLEGIESIDDDVFVLAFGDIIAPAEFYKSLMDTYIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKESST
LALGGAYILPKPKDNFTSLLDYIDLLSSQARLNYFIWSESWVDIGYPEDLLFALETLLRRKESVISDKAEISKNAIIGKG
VIIEDYAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIG
ASVITASYPAHSLSRPRFNKLGALISPEKVIKHGSVIEAGTKV

Sequences:

>Translated_363_residues
MSEMKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKGNQIEEEVEKLDVSFETIVQK
KQGIDGAVLEGIESIDDDVFVLAFGDIIAPAEFYKSLMDTYIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKESST
LALGGAYILPKPKDNFTSLLDYIDLLSSQARLNYFIWSESWVDIGYPEDLLFALETLLRRKESVISDKAEISKNAIIGKG
VIIEDYAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIG
ASVITASYPAHSLSRPRFNKLGALISPEKVIKHGSVIEAGTKV
>Mature_362_residues
SEMKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKGNQIEEEVEKLDVSFETIVQKK
QGIDGAVLEGIESIDDDVFVLAFGDIIAPAEFYKSLMDTYIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKESSTL
ALGGAYILPKPKDNFTSLLDYIDLLSSQARLNYFIWSESWVDIGYPEDLLFALETLLRRKESVISDKAEISKNAIIGKGV
IIEDYAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIGA
SVITASYPAHSLSRPRFNKLGALISPEKVIKHGSVIEAGTKV

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=345, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 39481; Mature: 39350

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKG
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
NQIEEEVEKLDVSFETIVQKKQGIDGAVLEGIESIDDDVFVLAFGDIIAPAEFYKSLMDT
CHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
YIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKESSTLALGGAYILPKPKDNFTSLL
HHHCCCCCEEEEEECCCCCCCCEEEEEECCHHHEEECCCEEEECCEEECCCCCCHHHHHH
DYIDLLSSQARLNYFIWSESWVDIGYPEDLLFALETLLRRKESVISDKAEISKNAIIGKG
HHHHHHCCCCCEEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
VIIEDYAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFA
EEEECHHHHHCCCEEECCCEECCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EVGSKSYLTYSIVGKGAKIGASVITASYPAHSLSRPRFNKLGALISPEKVIKHGSVIEAG
HHCCCCEEEEEEECCCCHHCHHHEEECCCCHHCCCCCHHHHCCCCCHHHHHHCCCEECCC
TKV
CCC
>Mature Secondary Structure 
SEMKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKG
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
NQIEEEVEKLDVSFETIVQKKQGIDGAVLEGIESIDDDVFVLAFGDIIAPAEFYKSLMDT
CHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
YIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKESSTLALGGAYILPKPKDNFTSLL
HHHCCCCCEEEEEECCCCCCCCEEEEEECCHHHEEECCCEEEECCEEECCCCCCHHHHHH
DYIDLLSSQARLNYFIWSESWVDIGYPEDLLFALETLLRRKESVISDKAEISKNAIIGKG
HHHHHHCCCCCEEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
VIIEDYAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFA
EEEECHHHHHCCCEEECCCEECCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EVGSKSYLTYSIVGKGAKIGASVITASYPAHSLSRPRFNKLGALISPEKVIKHGSVIEAG
HHCCCCEEEEEEECCCCHHCHHHEEECCCCHHCCCCCHHHHCCCCCHHHHHHCCCEECCC
TKV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]