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The map label for this gene is glmS-1 [H]

Identifier: 15897315

GI number: 15897315

Start: 325069

End: 326844

Strand: Reverse

Name: glmS-1 [H]

Synonym: SSO0382

Alternate gene names: 15897315

Gene position: 326844-325069 (Counterclockwise)

Preceding gene: 15897316

Following gene: 15897314

Centisome position: 10.92

GC content: 37.05

Gene sequence:

>1776_bases
GTGTGTGGAATTATAGGGATTGTGTCAAATAAGGAAAGTAATAGACTAGCTGAATTAGTAGTCTCATGCCTTAATAGATT
AGAGTATAGGGGTTATGATAGTGTTGGTGTTGCAGCACTTTCAGGCGGTAATTTAGAGGTCAGAAAGGCTAAAGGTACTG
TTGAGGAAGTAGTGAGAAAGAAAAATATTAAAGAATTATCTGGTTACGCATTTTTAGGACATACCAGATGGGCTACTCAT
GGAGCTCCTACTGATTACAATGCTCATCCTCACACAGATTGCATCAATAATATAGCAGTGATTCATAATGGAACAATAAG
GAACTTTAAAGAGCTAAGGGATGAGTTACAAGCTCTAGGCCATAAGTTCAAAAGCGAGACTGACACCGAAGTAATACCCC
ATATGATGGAGGAATACATGAAGAGAGGTATGGATACTTTTCAAGCGTTTAGAAGCGCAATAAAGAACATTCAAGGCAGT
TATGCAGTTTTAGCAATAGTTAAGGGAGAGAGAAGAATTTTCTTTGCAAAGAGAGATAACCCATTAGTAATAGGATTAGG
AGATGATAAGACGTTTGTGGCTAGTGATATACCTTCATTTTTACCTTATACTAGAAAGGTTATAGTAATATCTGATGGAG
AGCTAGGATATGTTACGCCAAATACTGTTTATATGGAAGACGAAAACGGTAATCCAATAGATGTTACAAGTAGAATAAAA
ATTATAGATTGGGACGCATCATCAGCCTCTAAGCAAGGATATCCTCACTTTATGCTTAAGGAAATCCATGAGAGCCCAAT
AGCTGTTAAAGACACAATTTCTGGACTTTTAAGTGAAGTTGATAAGATAAATGAAATCGCTGAGGAAATAAGAGAGTCCT
CTAGAATAATAGTTACAGCTGCAGGGACGAGTTATCACGCTGGACTATATTTCTCCCTATTACTTACAAGAAAGGGGTAT
ACGGTTATTCCATTAATTGCATCTGAATACCACAATTTTAGAGCTAGAAAGGGTGATATTGTACTTGCCATAAGTCAGAG
TGGAGAAACTCTCGACGTGAAAATGGGAATTAGGAAATTCAAGGATGAAGGGGCTAAGATAATTGCATTAACAAACGTAA
TTGAGAGCGACATAGCTAGGGAAAGTCATTACAAATTATATATGAGAGCTGGGCCAGAAATAGGGGTAGCTGCTACAAAA
ACTTTCACATCTGAGATAGTATCCTTACTTTTCTTATATTCCCTAATAGAAAAAGAAAGCATTTCGTATCTGGAAACTGC
TCATGAGACAGTTAGAAATGTAATAACTGAGACTGAAGGATTTGCTAAGAAGATTGGGGAGGAATTAGCTAACAAGAACA
ACGTTTATTATTTAGGAAGAGGTCTAGGAGTACCTTTAGCTATGGAAGGGGCATTAAAGATAAAGGAAATAGCATACATT
CATGCAGAAGCGTATCCAGCCGGCGAAAGTAAACATGGTCCAATAGCGTTAGTAGAGAGTGGATTTCCAATAATCTTCGT
AAATGATGGTGAACTAGTAGATGAATTAGAGAAGAATTTGCAAGAGATGAAAGCTAGAGGTGGCAAGACTTATTCAATAA
GTGTGAATAAGAGACTTAATTTCGCAGATACTGAAATTCTAGTAAATACTAGCGAAAAACTTTCTTCACTTGCCATAGCG
CCAATAATTCAACTTATTGCGTATTATGCTTCTGTTAAGAGAGGATATGATCCAGATAAGCCTAGGAACCTAGCGAAAAC
AGTAACGGTTGAGTGA

Upstream 100 bases:

>100_bases
AACGCTAGAATAGTTAATTCTACACTAACTAAAGATGGTGTCATTTTTTCGATACTATAAGGAAAAGTCTAATTTACCAG
TGCTTAAAAGATAGATTAAT

Downstream 100 bases:

>100_bases
AATGAAGGCTATAGTATTAGCTGGAGGAAAGGGAGAGGGACTGTTACCATATACTGAGAAGGTACAGAAAGAAGCTATTA
CAGTACTAGGTAAGGCAATA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MCGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRKKNIKELSGYAFLGHTRWATH
GAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALGHKFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGS
YAVLAIVKGERRIFFAKRDNPLVIGLGDDKTFVASDIPSFLPYTRKVIVISDGELGYVTPNTVYMEDENGNPIDVTSRIK
IIDWDASSASKQGYPHFMLKEIHESPIAVKDTISGLLSEVDKINEIAEEIRESSRIIVTAAGTSYHAGLYFSLLLTRKGY
TVIPLIASEYHNFRARKGDIVLAISQSGETLDVKMGIRKFKDEGAKIIALTNVIESDIARESHYKLYMRAGPEIGVAATK
TFTSEIVSLLFLYSLIEKESISYLETAHETVRNVITETEGFAKKIGEELANKNNVYYLGRGLGVPLAMEGALKIKEIAYI
HAEAYPAGESKHGPIALVESGFPIIFVNDGELVDELEKNLQEMKARGGKTYSISVNKRLNFADTEILVNTSEKLSSLAIA
PIIQLIAYYASVKRGYDPDKPRNLAKTVTVE

Sequences:

>Translated_591_residues
MCGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRKKNIKELSGYAFLGHTRWATH
GAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALGHKFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGS
YAVLAIVKGERRIFFAKRDNPLVIGLGDDKTFVASDIPSFLPYTRKVIVISDGELGYVTPNTVYMEDENGNPIDVTSRIK
IIDWDASSASKQGYPHFMLKEIHESPIAVKDTISGLLSEVDKINEIAEEIRESSRIIVTAAGTSYHAGLYFSLLLTRKGY
TVIPLIASEYHNFRARKGDIVLAISQSGETLDVKMGIRKFKDEGAKIIALTNVIESDIARESHYKLYMRAGPEIGVAATK
TFTSEIVSLLFLYSLIEKESISYLETAHETVRNVITETEGFAKKIGEELANKNNVYYLGRGLGVPLAMEGALKIKEIAYI
HAEAYPAGESKHGPIALVESGFPIIFVNDGELVDELEKNLQEMKARGGKTYSISVNKRLNFADTEILVNTSEKLSSLAIA
PIIQLIAYYASVKRGYDPDKPRNLAKTVTVE
>Mature_591_residues
MCGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRKKNIKELSGYAFLGHTRWATH
GAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALGHKFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGS
YAVLAIVKGERRIFFAKRDNPLVIGLGDDKTFVASDIPSFLPYTRKVIVISDGELGYVTPNTVYMEDENGNPIDVTSRIK
IIDWDASSASKQGYPHFMLKEIHESPIAVKDTISGLLSEVDKINEIAEEIRESSRIIVTAAGTSYHAGLYFSLLLTRKGY
TVIPLIASEYHNFRARKGDIVLAISQSGETLDVKMGIRKFKDEGAKIIALTNVIESDIARESHYKLYMRAGPEIGVAATK
TFTSEIVSLLFLYSLIEKESISYLETAHETVRNVITETEGFAKKIGEELANKNNVYYLGRGLGVPLAMEGALKIKEIAYI
HAEAYPAGESKHGPIALVESGFPIIFVNDGELVDELEKNLQEMKARGGKTYSISVNKRLNFADTEILVNTSEKLSSLAIA
PIIQLIAYYASVKRGYDPDKPRNLAKTVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=691, Percent_Identity=31.8379160636758, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=31.970802919708, Blast_Score=294, Evalue=1e-79,
Organism=Escherichia coli, GI1790167, Length=632, Percent_Identity=37.1835443037975, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1788651, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17539970, Length=429, Percent_Identity=31.9347319347319, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17532899, Length=429, Percent_Identity=31.2354312354312, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17532897, Length=429, Percent_Identity=31.2354312354312, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17554892, Length=233, Percent_Identity=26.6094420600858, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322745, Length=457, Percent_Identity=31.0722100656455, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323731, Length=431, Percent_Identity=24.1299303944316, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323730, Length=206, Percent_Identity=32.5242718446602, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323958, Length=203, Percent_Identity=25.615763546798, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357745, Length=688, Percent_Identity=30.6686046511628, Blast_Score=295, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65528; Mature: 65528

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRK
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCHHHHHHHH
KNIKELSGYAFLGHTRWATHGAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALG
CCHHHHCCEEEECCCCEECCCCCCCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHHHHH
HKFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGSYAVLAIVKGERRIFFAKRDN
HHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEECCC
PLVIGLGDDKTFVASDIPSFLPYTRKVIVISDGELGYVTPNTVYMEDENGNPIDVTSRIK
EEEEEECCCCEEEHHCCHHHCCCCEEEEEEECCCEEEECCCEEEEECCCCCEEEEECEEE
IIDWDASSASKQGYPHFMLKEIHESPIAVKDTISGLLSEVDKINEIAEEIRESSRIIVTA
EEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGTSYHAGLYFSLLLTRKGYTVIPLIASEYHNFRARKGDIVLAISQSGETLDVKMGIRKF
CCCCCCHHHHEEEEECCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCEEEEHHHHHHH
KDEGAKIIALTNVIESDIARESHYKLYMRAGPEIGVAATKTFTSEIVSLLFLYSLIEKES
HCCCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ISYLETAHETVRNVITETEGFAKKIGEELANKNNVYYLGRGLGVPLAMEGALKIKEIAYI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCEEEEHEEEE
HAEAYPAGESKHGPIALVESGFPIIFVNDGELVDELEKNLQEMKARGGKTYSISVNKRLN
EEECCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FADTEILVNTSEKLSSLAIAPIIQLIAYYASVKRGYDPDKPRNLAKTVTVE
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MCGIIGIVSNKESNRLAELVVSCLNRLEYRGYDSVGVAALSGGNLEVRKAKGTVEEVVRK
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCHHHHHHHH
KNIKELSGYAFLGHTRWATHGAPTDYNAHPHTDCINNIAVIHNGTIRNFKELRDELQALG
CCHHHHCCEEEECCCCEECCCCCCCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHHHHH
HKFKSETDTEVIPHMMEEYMKRGMDTFQAFRSAIKNIQGSYAVLAIVKGERRIFFAKRDN
HHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEECCC
PLVIGLGDDKTFVASDIPSFLPYTRKVIVISDGELGYVTPNTVYMEDENGNPIDVTSRIK
EEEEEECCCCEEEHHCCHHHCCCCEEEEEEECCCEEEECCCEEEEECCCCCEEEEECEEE
IIDWDASSASKQGYPHFMLKEIHESPIAVKDTISGLLSEVDKINEIAEEIRESSRIIVTA
EEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGTSYHAGLYFSLLLTRKGYTVIPLIASEYHNFRARKGDIVLAISQSGETLDVKMGIRKF
CCCCCCHHHHEEEEECCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCEEEEHHHHHHH
KDEGAKIIALTNVIESDIARESHYKLYMRAGPEIGVAATKTFTSEIVSLLFLYSLIEKES
HCCCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ISYLETAHETVRNVITETEGFAKKIGEELANKNNVYYLGRGLGVPLAMEGALKIKEIAYI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCEEEEHEEEE
HAEAYPAGESKHGPIALVESGFPIIFVNDGELVDELEKNLQEMKARGGKTYSISVNKRLN
EEECCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FADTEILVNTSEKLSSLAIAPIIQLIAYYASVKRGYDPDKPRNLAKTVTVE
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA