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The map label for this gene is rio2 [H]

Identifier: 15897147

GI number: 15897147

Start: 169763

End: 170626

Strand: Direct

Name: rio2 [H]

Synonym: SSO0197

Alternate gene names: 15897147

Gene position: 169763-170626 (Clockwise)

Preceding gene: 15897146

Following gene: 15897148

Centisome position: 5.67

GC content: 31.02

Gene sequence:

>864_bases
ATGAGACTTTCACTAGCGGAGAAAGCATCACTAGTGAGACCTTTCGACTATATATTATTAAAAACGATATATGGTCTTAG
GGATAAAAGTGAATTTGTTAGTTTTAATGCCTTAAAAAAGAGATTAGATATTAAAGACGATGAAGAACTAAAGATATCAC
TAAAGAAATTATCTGAGTTAAAACTTATTTCTAAAAAGCCAACAGATTTATCTTTCAAATTAACATTTTCTGGTCTGGAT
ATTTTGGGAATAAAACTGCTATATGTGAATAAAATCTTGAATAGATTAGCAGAGATAATAGGGATAGGAAAAGAAAGCTT
AGTATATTATGGGTATGATTTCAACGATAACAAAATAATAGTTAAATTTCATCGAGTAGGCACGGATAGTTATAAGAAAG
TTAAATTTAGAAAAAGCCAAGAAAAGAAAAGTTGGCTTTCAATTACCGTTGAAAATGCTAAAAGAGAGTTTGAAGCTCTT
ACATGTTTAAGCAATGAGGGAGGCTATGTCCCTAAGCCACTAGGAGTGGAATATAACGCCGTAGCAATGGAATATATCGA
TGGGATAGAGCTTTACAAAATACCAGTTACTAATATGGATCTAAACTTAGATGAAATCCTTGAAAAAATTTTACAAACCA
TGAGAATAGCTTACACTATTTGTCACATAACACATGGAGATTTAAGCCCGTATAATGTACTTATAGATAAAAACGGAAAT
CCTTATCTTATTGACTGGCCTCAAGCGACAAAATCTGAGGAAAGATTAGAAAAGGATCTATCAAATCTTATAATATTTTT
TAGAAAAAAGGGAATAGATGTAGATACTCGTAAGATTTTCGATTATGTAAGAGGGGTATCATGA

Upstream 100 bases:

>100_bases
GAACGCATTAAAAACAGAGATTGAAGATAAAATTCCGGGAAAGAGCAAGATAGTTAAGACAAGTATAACATATAATAGTT
AAAACTAATATAAAATAAGA

Downstream 100 bases:

>100_bases
AAATAATGGGAATTGATATAGAGGCGATGGAAAGCCCATCCTCTAAGTCACAGCCATTATATTCAGTTATTATTATTGAC
GAGAACGAAAAAATAGTCTA

Product: hypothetical protein

Products: NA

Alternate protein names: AfRio2 [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MRLSLAEKASLVRPFDYILLKTIYGLRDKSEFVSFNALKKRLDIKDDEELKISLKKLSELKLISKKPTDLSFKLTFSGLD
ILGIKLLYVNKILNRLAEIIGIGKESLVYYGYDFNDNKIIVKFHRVGTDSYKKVKFRKSQEKKSWLSITVENAKREFEAL
TCLSNEGGYVPKPLGVEYNAVAMEYIDGIELYKIPVTNMDLNLDEILEKILQTMRIAYTICHITHGDLSPYNVLIDKNGN
PYLIDWPQATKSEERLEKDLSNLIIFFRKKGIDVDTRKIFDYVRGVS

Sequences:

>Translated_287_residues
MRLSLAEKASLVRPFDYILLKTIYGLRDKSEFVSFNALKKRLDIKDDEELKISLKKLSELKLISKKPTDLSFKLTFSGLD
ILGIKLLYVNKILNRLAEIIGIGKESLVYYGYDFNDNKIIVKFHRVGTDSYKKVKFRKSQEKKSWLSITVENAKREFEAL
TCLSNEGGYVPKPLGVEYNAVAMEYIDGIELYKIPVTNMDLNLDEILEKILQTMRIAYTICHITHGDLSPYNVLIDKNGN
PYLIDWPQATKSEERLEKDLSNLIIFFRKKGIDVDTRKIFDYVRGVS
>Mature_287_residues
MRLSLAEKASLVRPFDYILLKTIYGLRDKSEFVSFNALKKRLDIKDDEELKISLKKLSELKLISKKPTDLSFKLTFSGLD
ILGIKLLYVNKILNRLAEIIGIGKESLVYYGYDFNDNKIIVKFHRVGTDSYKKVKFRKSQEKKSWLSITVENAKREFEAL
TCLSNEGGYVPKPLGVEYNAVAMEYIDGIELYKIPVTNMDLNLDEILEKILQTMRIAYTICHITHGDLSPYNVLIDKNGN
PYLIDWPQATKSEERLEKDLSNLIIFFRKKGIDVDTRKIFDYVRGVS

Specific function: Unknown

COG id: COG0478

COG function: function code T; RIO-like serine/threonine protein kinase fused to N-terminal HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI229331971, Length=229, Percent_Identity=27.9475982532751, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI229331967, Length=229, Percent_Identity=27.9475982532751, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32564178, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324122, Length=236, Percent_Identity=25, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649986, Length=231, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33154; Mature: 33154

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSLAEKASLVRPFDYILLKTIYGLRDKSEFVSFNALKKRLDIKDDEELKISLKKLSEL
CCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KLISKKPTDLSFKLTFSGLDILGIKLLYVNKILNRLAEIIGIGKESLVYYGYDFNDNKII
HHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEE
VKFHRVGTDSYKKVKFRKSQEKKSWLSITVENAKREFEALTCLSNEGGYVPKPLGVEYNA
EEEEECCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHEEECCCCCCCCCCCCCCHHH
VAMEYIDGIELYKIPVTNMDLNLDEILEKILQTMRIAYTICHITHGDLSPYNVLIDKNGN
HHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCC
PYLIDWPQATKSEERLEKDLSNLIIFFRKKGIDVDTRKIFDYVRGVS
EEEEECCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRLSLAEKASLVRPFDYILLKTIYGLRDKSEFVSFNALKKRLDIKDDEELKISLKKLSEL
CCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KLISKKPTDLSFKLTFSGLDILGIKLLYVNKILNRLAEIIGIGKESLVYYGYDFNDNKII
HHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEE
VKFHRVGTDSYKKVKFRKSQEKKSWLSITVENAKREFEALTCLSNEGGYVPKPLGVEYNA
EEEEECCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHEEECCCCCCCCCCCCCCHHH
VAMEYIDGIELYKIPVTNMDLNLDEILEKILQTMRIAYTICHITHGDLSPYNVLIDKNGN
HHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCC
PYLIDWPQATKSEERLEKDLSNLIIFFRKKGIDVDTRKIFDYVRGVS
EEEEECCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]