Click here to switch to the map view.

The map label for this gene is lysM

Identifier: 15897108

GI number: 15897108

Start: 131917

End: 132345

Strand: Direct

Name: lysM

Synonym: SSO0157

Alternate gene names: 15897108

Gene position: 131917-132345 (Clockwise)

Preceding gene: 15897107

Following gene: 15897109

Centisome position: 4.41

GC content: 33.1

Gene sequence:

>429_bases
ATGGGTAATGCAAATATTGATGAAAGTGATTTAAAAATATTAGAGATTCTGAAAAAGAACGCCAGAACACCTTACACATT
GATAGCCAAGGAGCTTAAGGTAAGCGAAGCCGCAATACGAAAAAGAATAGAGAAATTAATACGGCAAGGTATAATTAAGA
GATTTACTATAGAATATGAGCTAGAAAATGAGATTAGAGCAATAGTTATGGTTCAATCTACGCCACAAATACCGACACCA
GAAATATCTAAAAAGATAGCAAAAATTCCAGGAGTTGAAGTAGTATATGAAACTACTGGAGATTATGATATTCTAGTAAT
AGTTAGAGGGACAAACATTACATCAATCAATAGGACAATAGATGAGATTAGAAGCATTCAAGGTGTTGTGGGAACAAATA
GTACTATTATCCTTAGAACCTGGTTCTAA

Upstream 100 bases:

>100_bases
GAAAGTGTTGAGAACGGCGTTAATAAAGTAATAATAGGGTCTGGAGTTAAAGATAGACCAATTATCAATGCATTAGAACT
CAATGGGACGGTGATAGCGA

Downstream 100 bases:

>100_bases
AATCGTACCACTTATTACTAAAAACTTTTTCTACACAAAACTAAGTTAGTATCTAACTGACCTTCAATGGTAAATCTAAA
ATGTCCTATCTGTGGTGGAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MGNANIDESDLKILEILKKNARTPYTLIAKELKVSEAAIRKRIEKLIRQGIIKRFTIEYELENEIRAIVMVQSTPQIPTP
EISKKIAKIPGVEVVYETTGDYDILVIVRGTNITSINRTIDEIRSIQGVVGTNSTIILRTWF

Sequences:

>Translated_142_residues
MGNANIDESDLKILEILKKNARTPYTLIAKELKVSEAAIRKRIEKLIRQGIIKRFTIEYELENEIRAIVMVQSTPQIPTP
EISKKIAKIPGVEVVYETTGDYDILVIVRGTNITSINRTIDEIRSIQGVVGTNSTIILRTWF
>Mature_141_residues
GNANIDESDLKILEILKKNARTPYTLIAKELKVSEAAIRKRIEKLIRQGIIKRFTIEYELENEIRAIVMVQSTPQIPTPE
ISKKIAKIPGVEVVYETTGDYDILVIVRGTNITSINRTIDEIRSIQGVVGTNSTIILRTWF

Specific function: In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the diaminopimelate pathway

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYSM_SULSO (Q980W9)

Other databases:

- EMBL:   AE006641
- EMBL:   BK000545
- PIR:   H90155
- RefSeq:   NP_341713.1
- ProteinModelPortal:   Q980W9
- SMR:   Q980W9
- GeneID:   1453330
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0157
- NMPDR:   fig|273057.1.peg.136
- HOGENOM:   HBG740878
- OMA:   DYELENE
- ProtClustDB:   CLSK802584
- BioCyc:   SSOL273057:SSO0157-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00033
- SMART:   SM00344

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 16096; Mature: 15965

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00519 HTH_ASNC_1; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNANIDESDLKILEILKKNARTPYTLIAKELKVSEAAIRKRIEKLIRQGIIKRFTIEYE
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
LENEIRAIVMVQSTPQIPTPEISKKIAKIPGVEVVYETTGDYDILVIVRGTNITSINRTI
ECCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCHHHHHH
DEIRSIQGVVGTNSTIILRTWF
HHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure 
GNANIDESDLKILEILKKNARTPYTLIAKELKVSEAAIRKRIEKLIRQGIIKRFTIEYE
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
LENEIRAIVMVQSTPQIPTPEISKKIAKIPGVEVVYETTGDYDILVIVRGTNITSINRTI
ECCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCHHHHHH
DEIRSIQGVVGTNSTIILRTWF
HHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 12042311