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The map label for this gene is coaW [H]

Identifier: 15927704

GI number: 15927704

Start: 2181668

End: 2182471

Strand: Direct

Name: coaW [H]

Synonym: SA1932

Alternate gene names: 15927704

Gene position: 2181668-2182471 (Clockwise)

Preceding gene: 15927700

Following gene: 15927708

Centisome position: 77.51

GC content: 37.56

Gene sequence:

>804_bases
ATGAAAGTTGGCATTGACGCTGGCGGTACACTAATTAAAATCGTTCAAGAGCAAGATAACCAACGTACTTTTAAAACTGA
ATTAACTAAAAATATTGATCAAGTTGTGGAATGGTTAAACCAACAGCAAATTGAAAAATTATGCTTAACTGGAGGTAATG
CAGGTGTCATTGCTGAAAACATCAACATTCCTGCACAAATTTTTGTAGAGTTTGATGCTGCATCTCAAGGACTAGGTATT
TTGTTAAAAGAGCAAGGCCATGACTTAGCAGATTATATTTTTGCAAATGTTGGTACCGGTACGTCACTACATTATTTCGA
CGGCCAATCACAACGTCGTGTAGGCGGTATCGGTACAGGTGGAGGCATGATTCAAGGACTCGGTTATTTACTAAGTCAAA
TCACTGATTATAAACAGTTAACTGACATGGCACAACACGGTGATCGTAACACTATCGATTTAAAGGTTAGACATATTTAT
AAAGATACCGAACCACCCATTCCCGGTGATTTAACAGCAGCTAATTTTGGTCATGTACTACATCATTTAGATGCTGATTT
TACACCTAGCAATAAATTAGCAGCCGTTATTGGTGTCGTTGGCGAAGTTGTTACGACAATGGCCATTACTGTTGCACGTG
AATTTAAAACTGAAAATATCGTTTATATCGGTTCTTCATTCCATAATAACGCTTTATTACGCAAAGTTGTGGAAGATTAT
ACTGTGTTACGCGGTTGCAAACCGTACTATGTTGAAAACGGCGCATTTTCAGGTGCTATTGGTGCATTATATTTAGGTAA
ATAG

Upstream 100 bases:

>100_bases
TGGCATCAAATTTGTTAATAATTACTATTATTACTTGTTTTTTAGTCATTTTACTATACTATTATTTAAGGATAGACATT
AATAATGAGGTGGGAATCTT

Downstream 100 bases:

>100_bases
AAAAAGACCATTTATATGCGCGTTGTTTTAAATAAACGCTATATAAATGGCCTTTTATTTTATGGTCTACGTGTTTTGGA
ATACGTATTGTTCCATTTAT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-II; Pantothenic acid kinase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGI
LLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
TVLRGCKPYYVENGAFSGAIGALYLGK

Sequences:

>Translated_267_residues
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGI
LLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
TVLRGCKPYYVENGAFSGAIGALYLGK
>Mature_267_residues
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGI
LLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
TVLRGCKPYYVENGAFSGAIGALYLGK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG5146

COG function: function code H; Pantothenate kinase, acetyl-CoA regulated

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type II pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011602
- InterPro:   IPR014642
- InterPro:   IPR004567 [H]

Pfam domain/function: PF03630 Fumble [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 29025; Mature: 29025

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAEN
CEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
INIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTG
CCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHH
HHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
TVLRGCKPYYVENGAFSGAIGALYLGK
HHHHCCCCEEEECCCCCCCCCEEEECC
>Mature Secondary Structure
MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAEN
CEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
INIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTG
CCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
GGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHH
HHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDY
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
TVLRGCKPYYVENGAFSGAIGALYLGK
HHHHCCCCEEEECCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA