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The map label for this gene is luxS

Identifier: 15927708

GI number: 15927708

Start: 2186360

End: 2186830

Strand: Direct

Name: luxS

Synonym: SA1936

Alternate gene names: 15927708

Gene position: 2186360-2186830 (Clockwise)

Preceding gene: 15927704

Following gene: 15927712

Centisome position: 77.67

GC content: 33.97

Gene sequence:

>471_bases
ATGACAAAAATGAATGTTGAAAGTTTCAATTTAGATCATACTAAAGTGGTTGCCCCATTTATTAGATTAGCGGGAACGAT
GGAAGGATTAAACGGAGATGTCATTCACAAATACGACATTCGTTTCAAACAACCAAACAAAGAACATATGGATATGCCAG
GACTACATTCATTAGAACATTTAATGGCTGAAAATATTAGAAATCATAGTGACAAAGTTGTTGATTTAAGTCCTATGGGT
TGCCAAACTGGTTTCTATGTATCATTTATTAATCATGATAATTATGATGATGTATTAAATATTGTTGAAGCAACTTTAAA
TGATGTGCTAAATGCTACTGAAGTGCCTGCTTGTAATGAAGTACAATGTGGCTGGGCAGCAAGTCATTCATTAGAAGGTG
CTAAAACTATCGCTCAAGCATTTCTAGACAAACGAAACGAATGGCATGATGTTTTCGGTACAGGAAAATAA

Upstream 100 bases:

>100_bases
AGTATTGTTAGAAACACAACTTACAACAAACTTAAGTTTTATATTGCAACAAATCATAAGCGTTTTATAGTTTTGAGTAG
TAAATAGGAGGAAATTCAAA

Downstream 100 bases:

>100_bases
ATCTTAGTCAATCAAGTTAATCAGAAAAGCAGTCGAACAATGATGTTACAATCGCCATTGTCCAACTGCTTTTTATTATG
CTTCAAAGTCAAAAAATCGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMG
CQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK

Sequences:

>Translated_156_residues
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMG
CQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
>Mature_155_residues
TKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGC
QTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=41.7808219178082, Blast_Score=120, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_STAA1 (A7X4Y8)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442708.1
- ProteinModelPortal:   A7X4Y8
- SMR:   A7X4Y8
- STRING:   A7X4Y8
- EnsemblBacteria:   EBSTAT00000003918
- GeneID:   5559239
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2118
- eggNOG:   COG1854
- GeneTree:   EBGT00050000025271
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- BioCyc:   SAUR418127:SAHV_2118-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17514; Mature: 17383

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECEECCCCHHHCCCCCHHHHHH
LMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNE
HHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
TKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEH
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECEECCCCHHHCCCCCHHHHHH
LMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNE
HHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA