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The map label for this gene is malR

Identifier: 15927089

GI number: 15927089

Start: 1546978

End: 1547997

Strand: Reverse

Name: malR

Synonym: SA1339

Alternate gene names: 15927089

Gene position: 1547997-1546978 (Counterclockwise)

Preceding gene: 15927090

Following gene: 15927088

Centisome position: 54.99

GC content: 31.47

Gene sequence:

>1020_bases
ATGGTTACGATTAAAGATGTTGCACTAAAAGCCGGTGTTTCTCCTTCGACAGTTTCAAGAGTTATAAAAGGAAATAAACG
TATTAGCGAAGCGACAATTTCAAAAGTGAAGAAAGTTATGGAAGAATTGAATTATTTTCCTAATACCGCTGCTAGAACTT
TAATTACAAACCAAACATATAAAATTGGTTTAGTGTTAAAAGGGTCTGAGGAGCCTATTCGACTGAATCCATTCTACATC
AATGTATTGCTAGGAATTTCTGAAACGTGTAACCAGCATGGCTATGGTACACAAACGACAGTCTCAAATAATATGAATGA
TTTAATGGATGAAGTTTATAAAATGATTAAACAACGAATGGTTGATGCGTTTATACTGCTTTATTCAAAAGAAAATGATC
CAATTAAACAAATGTTAATTGATGAAAGCATGCCATTTATTGTGATTGGTAAGCCTACATCGGATATAGATCATCAATTT
ACACACATAGATAATGATAATATATTAGCTTCTGAAAATTTGACACGACATGTTATTGAACAAGGTGTAGATGAATTAAT
ATTTATTACAGAAAAAGGAAATTTTGAAGTTTCAAAAGATAGAATTCAAGGATTTGAAACGGTTGCATCACAATTTAATC
TGGATTATCAAATTATTGAGACTAGTAATGAAAGAGAAGTTATTTTAAATTACATGCAAAATCTACATACGCGTTTGAAG
GACCCAAATATTAAACAGGCAATCATTTCGTTAGATGCTATGTTACATTTAGCGATTTTAAGTGTCCTATATGAACTTAA
TATTGAAATTCCGAAAGATGTAATGACAGCAACGTTCAATGATTCTTATTTAACCGAAATTGCGTCACCACCTCAAACCT
GTATTGACATCAAGCCTCGAATGTTAGGTCAACAGGCTGGTTCAGCAATTTTAAATATATTGAAAAACAAAGCACAGGAT
GTTATTGAACTCGTCATTATAGATACAGAATTAAAAATAAGAAAATCAACACAGCGATAG

Upstream 100 bases:

>100_bases
TTGCACAAATCTTTTGACTTTTTTAGAAAGAGTAACTAAACTGTTATTATATAGAGGTTGGAAGCGTTTTCCAATGCAGA
AATTAACAGGAGGTGATTAA

Downstream 100 bases:

>100_bases
CAAAGGAGTTTTAAAATGAATAAGCAATGGTGGAAAGAAGCAGTAGCATATCAAGTATATCCAAGAAGTTTTAATGATAG
TAATCACGATGGTATTGGGG

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVTIKDVALKAGVSPSTVSRVIKGNKRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETVASQFNLDYQIIETSNEREVILNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPRMLGQQAGSAILNILKNKAQD
VIELVIIDTELKIRKSTQR

Sequences:

>Translated_339_residues
MVTIKDVALKAGVSPSTVSRVIKGNKRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETVASQFNLDYQIIETSNEREVILNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPRMLGQQAGSAILNILKNKAQD
VIELVIIDTELKIRKSTQR
>Mature_339_residues
MVTIKDVALKAGVSPSTVSRVIKGNKRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETVASQFNLDYQIIETSNEREVILNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPRMLGQQAGSAILNILKNKAQD
VIELVIIDTELKIRKSTQR

Specific function: Transcriptional repressor of the malA gene for maltase [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790194, Length=310, Percent_Identity=27.0967741935484, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787948, Length=327, Percent_Identity=25.9938837920489, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1790369, Length=348, Percent_Identity=25.5747126436782, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787906, Length=233, Percent_Identity=26.1802575107296, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786268, Length=293, Percent_Identity=25.938566552901, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789202, Length=312, Percent_Identity=24.0384615384615, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=23.98753894081, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=21.8543046357616, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789456, Length=351, Percent_Identity=23.9316239316239, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786540, Length=324, Percent_Identity=23.4567901234568, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI48994940, Length=294, Percent_Identity=22.7891156462585, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38379; Mature: 38379

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKDVALKAGVSPSTVSRVIKGNKRISEATISKVKKVMEELNYFPNTAARTLITNQTY
CEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEE
KIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRM
EEEEEEECCCCCEEECCEEEEEEECCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQFTHIDNDNILASENLTRHVIE
HHHHEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCEEECCHHHHHHHH
QGVDELIFITEKGNFEVSKDRIQGFETVASQFNLDYQIIETSNEREVILNYMQNLHTRLK
CCCCCEEEEEECCCCEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCC
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCHHHHHHCCCCCHHHCCCHH
MLGQQAGSAILNILKNKAQDVIELVIIDTELKIRKSTQR
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCC
>Mature Secondary Structure
MVTIKDVALKAGVSPSTVSRVIKGNKRISEATISKVKKVMEELNYFPNTAARTLITNQTY
CEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEE
KIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRM
EEEEEEECCCCCEEECCEEEEEEECCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQFTHIDNDNILASENLTRHVIE
HHHHEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCEEECCHHHHHHHH
QGVDELIFITEKGNFEVSKDRIQGFETVASQFNLDYQIIETSNEREVILNYMQNLHTRLK
CCCCCEEEEEECCCCEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCC
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCHHHHHHCCCCCHHHCCCHH
MLGQQAGSAILNILKNKAQDVIELVIIDTELKIRKSTQR
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7730272 [H]