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The map label for this gene is hslV

Identifier: 16127957

GI number: 16127957

Start: 3983658

End: 3984224

Strand: Direct

Name: hslV

Synonym: CC_3727

Alternate gene names: 16127957

Gene position: 3983658-3984224 (Clockwise)

Preceding gene: 16127953

Following gene: 16127958

Centisome position: 99.17

GC content: 68.08

Gene sequence:

>567_bases
ATGCAAAGCAACAGCTCTTCCTTCCCCGACTGGCACGGCACGACCATTCTGGCGGTGCGCAAGAACGGCTCGACCGTGAT
CGCCGGCGACGGACAGGTCTCCATGGGCCCAACCGTCGTCAAGGGCAACGCCCGCAAGGTGCGTCGCCTGGCCGGCGGCA
AGGTGGTCGCGGGCTTCGCCGGCGCCACGGCCGACGCCTTCACCCTGATTGAACGGCTGGAGGCCAAGCTGGAGCAGTAT
CCCGACCAGTTGGCCCGCGCTTGCGTCGATCTGGCCAAGGACTGGCGGACCGACCGCTATCTGCGCCGGCTGGAAGCCAT
GCTGCTGGTGGCCGACAAGACCGCCATCTACACCGTCACCGGCGTCGGCGATGTTCTGGAGCCCGGCGAGAGCCTCGGCG
GCGGGGCGGTCGCGGCCATCGGCTCGGGCGGCAACTACGCCCTGGCGGCCGGCAAGGCCTTGATCGATCTGGACCTCTCG
GCCGAGGACATCGCCCGCAAGGCGATGGGCATCGCCGCCGAGATCTGCGTCTACACCAACGGCAACCTGACCGTCGAAAG
CCTGTAA

Upstream 100 bases:

>100_bases
ACTTCGCGCAGCACCAGATGGCGGGCGTACCGCTCGACCTCGCCGTCGGAAAAACTCATGGCGCTTGACCCTCCGCCCCG
GCCTCGCCACATGCGAAGCC

Downstream 100 bases:

>100_bases
TGACCGAGTTTTCGCCCCGCGAGATCGTTTCCGAACTGGACCGCTACATCGTCGGTCACGCCGAGGCCAAGAAGGCCGTC
GCCGTGGCCCTGCGCAACCG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MQSNSSSFPDWHGTTILAVRKNGSTVIAGDGQVSMGPTVVKGNARKVRRLAGGKVVAGFAGATADAFTLIERLEAKLEQY
PDQLARACVDLAKDWRTDRYLRRLEAMLLVADKTAIYTVTGVGDVLEPGESLGGGAVAAIGSGGNYALAAGKALIDLDLS
AEDIARKAMGIAAEICVYTNGNLTVESL

Sequences:

>Translated_188_residues
MQSNSSSFPDWHGTTILAVRKNGSTVIAGDGQVSMGPTVVKGNARKVRRLAGGKVVAGFAGATADAFTLIERLEAKLEQY
PDQLARACVDLAKDWRTDRYLRRLEAMLLVADKTAIYTVTGVGDVLEPGESLGGGAVAAIGSGGNYALAAGKALIDLDLS
AEDIARKAMGIAAEICVYTNGNLTVESL
>Mature_188_residues
MQSNSSSFPDWHGTTILAVRKNGSTVIAGDGQVSMGPTVVKGNARKVRRLAGGKVVAGFAGATADAFTLIERLEAKLEQY
PDQLARACVDLAKDWRTDRYLRRLEAMLLVADKTAIYTVTGVGDVLEPGESLGGGAVAAIGSGGNYALAAGKALIDLDLS
AEDIARKAMGIAAEICVYTNGNLTVESL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=176, Percent_Identity=58.5227272727273, Blast_Score=197, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_CAUCR (Q9A239)

Other databases:

- EMBL:   AE005673
- PIR:   E87711
- RefSeq:   NP_422521.1
- ProteinModelPortal:   Q9A239
- SMR:   Q9A239
- MEROPS:   T01.006
- GeneID:   940618
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_3727
- NMPDR:   fig|190650.1.peg.3701
- TIGR:   CC_3727
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19601; Mature: 19601

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: ACT_SITE 14-14

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSNSSSFPDWHGTTILAVRKNGSTVIAGDGQVSMGPTVVKGNARKVRRLAGGKVVAGFA
CCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCEEEECCHHHHHHHCCCEEEEECC
GATADAFTLIERLEAKLEQYPDQLARACVDLAKDWRTDRYLRRLEAMLLVADKTAIYTVT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEE
GVGDVLEPGESLGGGAVAAIGSGGNYALAAGKALIDLDLSAEDIARKAMGIAAEICVYTN
CCCCHHCCCCCCCCCEEEEEECCCCEEEECCCEEEEECCCHHHHHHHHHCCEEEEEEEEC
GNLTVESL
CCEEEEEC
>Mature Secondary Structure
MQSNSSSFPDWHGTTILAVRKNGSTVIAGDGQVSMGPTVVKGNARKVRRLAGGKVVAGFA
CCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCEEEECCHHHHHHHCCCEEEEECC
GATADAFTLIERLEAKLEQYPDQLARACVDLAKDWRTDRYLRRLEAMLLVADKTAIYTVT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEE
GVGDVLEPGESLGGGAVAAIGSGGNYALAAGKALIDLDLSAEDIARKAMGIAAEICVYTN
CCCCHHCCCCCCCCCEEEEEECCCCEEEECCCEEEEECCCHHHHHHHHHCCEEEEEEEEC
GNLTVESL
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647