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The map label for this gene is ccmA

Identifier: 16127898

GI number: 16127898

Start: 3924209

End: 3924823

Strand: Direct

Name: ccmA

Synonym: CC_3668

Alternate gene names: 16127898

Gene position: 3924209-3924823 (Clockwise)

Preceding gene: 16127893

Following gene: 16127899

Centisome position: 97.69

GC content: 70.24

Gene sequence:

>615_bases
GTGTTGAGAGCTGTTCTCATTAAGGATCTGGCGATTTCGCGCGGTGAGCGAACGCTGTTTTCCAAGCTGGATCTGACACT
TCGCGCCGGCGAGGCCGCGACCCTGGTGGGACGAAATGGCGCGGGCAAGACCAGCCTTTTGCGCGCCGTGGCGGGCCTTT
TGCGCCCGGCCGCCGGTTCGACCGCCTTCGAGGACGCGAACGGCCCGGTCGAGGCGGACACCGCCCGCGCCGAACATCTG
CACATGCTGGGTCACCAGGATGGTCTGAAGTCCAGTCGCACAGCCTGGGAAGAGCTCCGCTTCCAGACCCTGTGGACCGG
CGGCAACGAGGACAGCGCCCGCGCCGCCGCCCAGCGATTCGACCTGCGCCGCTTGCTGGATCTGGAGGTGCGACGCCTCT
CCGCCGGTCAGCGCCGCCGCCTGGCCCTGGCCCGCCTGGCGGCCAGCCCACGCTCGCTCTGGCTTCTCGACGAACCGATG
GCCCCGCTGGACGCGGGCCAACGCGCGGCGTTCGGCGCGGTGATGGCCGAGCACGTCGCCGGCGGGGGCATGATCCTCGC
CTCGGTCCACGATCCCTTGCCCATCCCGGCCCGCAGCGTGGAGGTCGGCGCATGA

Upstream 100 bases:

>100_bases
CCTCCGCGCCGCGTACCACCCTGAACGACTGGAGGGGGGCGACCGGCCGCTTCTTAGCGCCGCCGTCGACCAACGTCCAT
GTCACGTGCGGGGTCTTGGC

Downstream 100 bases:

>100_bases
GGGCGTTCGGAATCCTGCTGCGGCGCGAGTTGGCCCTGGCCTGGGGCAAGGGCGGCGGGCCGCTTCTGGCCCTTACCTTC
TACGCCTGCGTTGTCGTGCT

Product: heme exporter protein A

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLRAVLIKDLAISRGERTLFSKLDLTLRAGEAATLVGRNGAGKTSLLRAVAGLLRPAAGSTAFEDANGPVEADTARAEHL
HMLGHQDGLKSSRTAWEELRFQTLWTGGNEDSARAAAQRFDLRRLLDLEVRRLSAGQRRRLALARLAASPRSLWLLDEPM
APLDAGQRAAFGAVMAEHVAGGGMILASVHDPLPIPARSVEVGA

Sequences:

>Translated_204_residues
MLRAVLIKDLAISRGERTLFSKLDLTLRAGEAATLVGRNGAGKTSLLRAVAGLLRPAAGSTAFEDANGPVEADTARAEHL
HMLGHQDGLKSSRTAWEELRFQTLWTGGNEDSARAAAQRFDLRRLLDLEVRRLSAGQRRRLALARLAASPRSLWLLDEPM
APLDAGQRAAFGAVMAEHVAGGGMILASVHDPLPIPARSVEVGA
>Mature_204_residues
MLRAVLIKDLAISRGERTLFSKLDLTLRAGEAATLVGRNGAGKTSLLRAVAGLLRPAAGSTAFEDANGPVEADTARAEHL
HMLGHQDGLKSSRTAWEELRFQTLWTGGNEDSARAAAQRFDLRRLLDLEVRRLSAGQRRRLALARLAASPRSLWLLDEPM
APLDAGQRAAFGAVMAEHVAGGGMILASVHDPLPIPARSVEVGA

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Escherichia coli, GI87082064, Length=194, Percent_Identity=38.1443298969072, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790739, Length=195, Percent_Identity=30.2564102564103, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI2367384, Length=192, Percent_Identity=28.6458333333333, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=171, Percent_Identity=29.2397660818713, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87081709, Length=169, Percent_Identity=31.3609467455621, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081782, Length=169, Percent_Identity=33.7278106508876, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788225, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786803, Length=194, Percent_Identity=27.8350515463918, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788002, Length=190, Percent_Identity=32.6315789473684, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_CAUCR (Q9A298)

Other databases:

- EMBL:   AE005673
- PIR:   B87704
- RefSeq:   NP_422462.1
- ProteinModelPortal:   Q9A298
- SMR:   Q9A298
- GeneID:   940662
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_3668
- NMPDR:   fig|190650.1.peg.3642
- TIGR:   CC_3668
- HOGENOM:   HBG758042
- OMA:   VRRPIWL
- ProtClustDB:   CLSK891634
- BRENDA:   3.6.3.41
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 21813; Mature: 21813

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRAVLIKDLAISRGERTLFSKLDLTLRAGEAATLVGRNGAGKTSLLRAVAGLLRPAAGS
CCHHHHHHHHHHCCCCHHHHHHHCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
TAFEDANGPVEADTARAEHLHMLGHQDGLKSSRTAWEELRFQTLWTGGNEDSARAAAQRF
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
DLRRLLDLEVRRLSAGQRRRLALARLAASPRSLWLLDEPMAPLDAGQRAAFGAVMAEHVA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHC
GGGMILASVHDPLPIPARSVEVGA
CCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRAVLIKDLAISRGERTLFSKLDLTLRAGEAATLVGRNGAGKTSLLRAVAGLLRPAAGS
CCHHHHHHHHHHCCCCHHHHHHHCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
TAFEDANGPVEADTARAEHLHMLGHQDGLKSSRTAWEELRFQTLWTGGNEDSARAAAQRF
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
DLRRLLDLEVRRLSAGQRRRLALARLAASPRSLWLLDEPMAPLDAGQRAAFGAVMAEHVA
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHC
GGGMILASVHDPLPIPARSVEVGA
CCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11259647