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The map label for this gene is cycW [H]

Identifier: 16127899

GI number: 16127899

Start: 3924820

End: 3925485

Strand: Direct

Name: cycW [H]

Synonym: CC_3669

Alternate gene names: 16127899

Gene position: 3924820-3925485 (Clockwise)

Preceding gene: 16127898

Following gene: 16127902

Centisome position: 97.71

GC content: 74.77

Gene sequence:

>666_bases
ATGAGGGCGTTCGGAATCCTGCTGCGGCGCGAGTTGGCCCTGGCCTGGGGCAAGGGCGGCGGGCCGCTTCTGGCCCTTAC
CTTCTACGCCTGCGTTGTCGTGCTCTTGCCCATGGCGTCCGGCCGCGCCCCCGAGCGTCTGGCCGCCATCGCCCCGGGCA
TCGCCTGGCTGGCCCTGGCCCTGGCGGCGCTGCTGTCGCTGGAGCGTCTGTTTGAGCGCGACTACGAGGACGGCACGCTC
GACCTGCTCGCCATGGGCCCCGCGCCGCTGGAAGCCGTGGCGGTGGCCAAGTGCCTGGCCCAGTGGCTGGCGACCGGCGC
GCCGCTGGCCCTGGCGGCGCCGGTCGCGGCCCTGATGCTGGGCGCGGACCCCAAGGTCATGCCGCTGCTGGTGCTGTGCG
CCCTCGCCGGCGGCCTCGCCTTCGCCTTCCTGGGCGGTCTGGGCGCCGCGTTGGCGCTGGGGAGCAAGCGCGGAGGCCTG
CTGGTCGCCGTGATCGTGCTGCCGCTGTTCGCGCCGCCGGTGATCTTCGGGGCCGGCGCCCTGGACGGCTATGCGGCCGG
CCTGCCCTGGACCGGCGGCCTTCTGCTCCTGCTGGCCTACAGCGCCGGGGCGGTCGCGCTGACCCCGCTCGCCATGGGCG
CAGCCTGCCGCAACGCTCTGGATTGA

Upstream 100 bases:

>100_bases
TCGGCGCGGTGATGGCCGAGCACGTCGCCGGCGGGGGCATGATCCTCGCCTCGGTCCACGATCCCTTGCCCATCCCGGCC
CGCAGCGTGGAGGTCGGCGC

Downstream 100 bases:

>100_bases
GCCGATAGACTGTCATCCCGGCTAAGCGCAAAGCGCGCAGAGCCGGGATGACAGCTTTTACGGCGTCGGCGCGACGGTGG
CTTGGATCTCGCCAGGCTTG

Product: heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRAFGILLRRELALAWGKGGGPLLALTFYACVVVLLPMASGRAPERLAAIAPGIAWLALALAALLSLERLFERDYEDGTL
DLLAMGPAPLEAVAVAKCLAQWLATGAPLALAAPVAALMLGADPKVMPLLVLCALAGGLAFAFLGGLGAALALGSKRGGL
LVAVIVLPLFAPPVIFGAGALDGYAAGLPWTGGLLLLLAYSAGAVALTPLAMGAACRNALD

Sequences:

>Translated_221_residues
MRAFGILLRRELALAWGKGGGPLLALTFYACVVVLLPMASGRAPERLAAIAPGIAWLALALAALLSLERLFERDYEDGTL
DLLAMGPAPLEAVAVAKCLAQWLATGAPLALAAPVAALMLGADPKVMPLLVLCALAGGLAFAFLGGLGAALALGSKRGGL
LVAVIVLPLFAPPVIFGAGALDGYAAGLPWTGGLLLLLAYSAGAVALTPLAMGAACRNALD
>Mature_221_residues
MRAFGILLRRELALAWGKGGGPLLALTFYACVVVLLPMASGRAPERLAAIAPGIAWLALALAALLSLERLFERDYEDGTL
DLLAMGPAPLEAVAVAKCLAQWLATGAPLALAAPVAALMLGADPKVMPLLVLCALAGGLAFAFLGGLGAALALGSKRGGL
LVAVIVLPLFAPPVIFGAGALDGYAAGLPWTGGLLLLLAYSAGAVALTPLAMGAACRNALD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=218, Percent_Identity=41.2844036697248, Blast_Score=120, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22189; Mature: 22189

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFGILLRRELALAWGKGGGPLLALTFYACVVVLLPMASGRAPERLAAIAPGIAWLALA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
LAALLSLERLFERDYEDGTLDLLAMGPAPLEAVAVAKCLAQWLATGAPLALAAPVAALML
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GADPKVMPLLVLCALAGGLAFAFLGGLGAALALGSKRGGLLVAVIVLPLFAPPVIFGAGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
LDGYAAGLPWTGGLLLLLAYSAGAVALTPLAMGAACRNALD
CCCHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAFGILLRRELALAWGKGGGPLLALTFYACVVVLLPMASGRAPERLAAIAPGIAWLALA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
LAALLSLERLFERDYEDGTLDLLAMGPAPLEAVAVAKCLAQWLATGAPLALAAPVAALML
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GADPKVMPLLVLCALAGGLAFAFLGGLGAALALGSKRGGLLVAVIVLPLFAPPVIFGAGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
LDGYAAGLPWTGGLLLLLAYSAGAVALTPLAMGAACRNALD
CCCHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]