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The map label for this gene is dapB

Identifier: 16127780

GI number: 16127780

Start: 3799018

End: 3799791

Strand: Direct

Name: dapB

Synonym: CC_3550

Alternate gene names: 16127780

Gene position: 3799018-3799791 (Clockwise)

Preceding gene: 16127769

Following gene: 16127781

Centisome position: 94.57

GC content: 70.8

Gene sequence:

>774_bases
TTGTCCCAGCCCGTGAAGATCGCGATCGCCGGCGCCAATGGCCGCATGGGCCGCGCCGTCGCCCAGGCGCTGGAAGGTCG
GAGCGACGCCGTGGTCGCCGCCCGCTTCGAGCGTCCCGGCGACGCGGGCGAAGGCCTTGTCGCGCGCGAGACCGCCCTGG
CCGCCGCCGAGGCGGTGATCGACTTCACCCTGCCCGAGGCCTCGGTCGCCCTGGCCGAAGAGGCCGCCGCGAACGGCGGT
CCGGCGCTGGTCATCGGCTCCACCGGGTTCTCGGACGAGCAGCTGGACCGCATCGACGCGGCCGCCACGAAGATCGTCAT
CGTCCGCTCGGGCAACTATTCGCTGGGCGTCAACATGCTGATGGGCCTGGTGCGTCAGGCCGCCGCCGCCCTGCCGGCTC
AGGATTGGGATATCGAAGTCTTCGAGGCCCACCACAAGCGCAAGATCGACGCCCCGTCGGGCACGGCCCTGATGCTGGGC
GAAGCGGCCGCCGAAGGACGAGGCATCAACCTCGCCAAGGTCTCGGACCGCGGCCGCGACGGCGTCACCGGTCCCCGCAA
GGATGGCGACATCGGCTTTTCGGTGGTGCGCGGCGGCGGGATCATCGGCGAGCACAGCGTGATCTTCGCCGGCGAGAGCG
AGAGCCTGACCCTGTCACACTCGGCCATCGACCGGGGCCTGTTCGCGCGCGGCGCCATCGCCGCCGCCGTCTGGGTCAAG
GGCAAGCCGCCAGGCCTCTACGACATGCAGGACGTGCTGGGCTTCAAGAAATAG

Upstream 100 bases:

>100_bases
TTGCGTCAAGCGCGACGCCCTCGGGGAAGGCGGCGTGAGGTTGACCTGAAGGGGCGGAACAGGTGATTTGCCCAAGGTCA
GTTTTCTCCCGGAGTCCGCC

Downstream 100 bases:

>100_bases
GGATCCAAAGCTTGGCCGGGGGGCTTTGTTAGGACACCAGACGCCAGGACGTGATGGCCGAAGCCTCGACCGAACCGACG
CCAGACAACGCGGCCAGAAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSQPVKIAIAGANGRMGRAVAQALEGRSDAVVAARFERPGDAGEGLVARETALAAAEAVIDFTLPEASVALAEEAAANGG
PALVIGSTGFSDEQLDRIDAAATKIVIVRSGNYSLGVNMLMGLVRQAAAALPAQDWDIEVFEAHHKRKIDAPSGTALMLG
EAAAEGRGINLAKVSDRGRDGVTGPRKDGDIGFSVVRGGGIIGEHSVIFAGESESLTLSHSAIDRGLFARGAIAAAVWVK
GKPPGLYDMQDVLGFKK

Sequences:

>Translated_257_residues
MSQPVKIAIAGANGRMGRAVAQALEGRSDAVVAARFERPGDAGEGLVARETALAAAEAVIDFTLPEASVALAEEAAANGG
PALVIGSTGFSDEQLDRIDAAATKIVIVRSGNYSLGVNMLMGLVRQAAAALPAQDWDIEVFEAHHKRKIDAPSGTALMLG
EAAAEGRGINLAKVSDRGRDGVTGPRKDGDIGFSVVRGGGIIGEHSVIFAGESESLTLSHSAIDRGLFARGAIAAAVWVK
GKPPGLYDMQDVLGFKK
>Mature_256_residues
SQPVKIAIAGANGRMGRAVAQALEGRSDAVVAARFERPGDAGEGLVARETALAAAEAVIDFTLPEASVALAEEAAANGGP
ALVIGSTGFSDEQLDRIDAAATKIVIVRSGNYSLGVNMLMGLVRQAAAALPAQDWDIEVFEAHHKRKIDAPSGTALMLGE
AAAEGRGINLAKVSDRGRDGVTGPRKDGDIGFSVVRGGGIIGEHSVIFAGESESLTLSHSAIDRGLFARGAIAAAVWVKG
KPPGLYDMQDVLGFKK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=266, Percent_Identity=40.9774436090226, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CAUCR (Q9A2L1)

Other databases:

- EMBL:   AE005673
- PIR:   D87689
- RefSeq:   NP_422344.1
- ProteinModelPortal:   Q9A2L1
- SMR:   Q9A2L1
- GeneID:   943731
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_3550
- NMPDR:   fig|190650.1.peg.3524
- TIGR:   CC_3550
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26425; Mature: 26294

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPVKIAIAGANGRMGRAVAQALEGRSDAVVAARFERPGDAGEGLVARETALAAAEAVI
CCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHE
DFTLPEASVALAEEAAANGGPALVIGSTGFSDEQLDRIDAAATKIVIVRSGNYSLGVNML
EEECCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCEEEEEEEECCCCCCCHHHH
MGLVRQAAAALPAQDWDIEVFEAHHKRKIDAPSGTALMLGEAAAEGRGINLAKVSDRGRD
HHHHHHHHHHCCCCCCCCCEEEHHHHEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCC
GVTGPRKDGDIGFSVVRGGGIIGEHSVIFAGESESLTLSHSAIDRGLFARGAIAAAVWVK
CCCCCCCCCCCCEEEEECCCEECCCEEEEECCCCCEEEEHHHHHHHHHHHCCEEEEEEEC
GKPPGLYDMQDVLGFKK
CCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SQPVKIAIAGANGRMGRAVAQALEGRSDAVVAARFERPGDAGEGLVARETALAAAEAVI
CCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHE
DFTLPEASVALAEEAAANGGPALVIGSTGFSDEQLDRIDAAATKIVIVRSGNYSLGVNML
EEECCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCEEEEEEEECCCCCCCHHHH
MGLVRQAAAALPAQDWDIEVFEAHHKRKIDAPSGTALMLGEAAAEGRGINLAKVSDRGRD
HHHHHHHHHHCCCCCCCCCEEEHHHHEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCC
GVTGPRKDGDIGFSVVRGGGIIGEHSVIFAGESESLTLSHSAIDRGLFARGAIAAAVWVK
CCCCCCCCCCCCEEEEECCCEECCCEEEEECCCCCEEEEHHHHHHHHHHHCCEEEEEEEC
GKPPGLYDMQDVLGFKK
CCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647