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The map label for this gene is luxQ [H]

Identifier: 16127449

GI number: 16127449

Start: 3480606

End: 3482579

Strand: Direct

Name: luxQ [H]

Synonym: CC_3219

Alternate gene names: 16127449

Gene position: 3480606-3482579 (Clockwise)

Preceding gene: 16127444

Following gene: 16127450

Centisome position: 86.65

GC content: 66.46

Gene sequence:

>1974_bases
TTGTTTTGTCGCGCAACTCTCCTTTCGGATGGAAGCGAAGCGTTAGGAACATTCAGGCATACTCTCGCCAAGAGTGAAGT
GCTGGGTGCGATGTCCGAAAACCGCAACCATAACGTGTCAAGCCACGCGCCGCTGCAGGCGCGAATCGCCGGTGTGGCCC
TGGCCACGACGGTGCTTGCGCTCGTGGCCGCCTGCCTTTGCTTCATGCTTCAACAATGGAGCGTGGCGCGCCAGGAGGCG
CGCGCCAACCACGAGGTGCTGGTGCAGATGGCCGCCGCCGGAGCCGCGGCCCCGCTGGCGGACCACAACATGGTCGGCGT
CTATCGAGCCCTGGAAGCCGTGGCCAAGGCGCCGGGCGTCGCCGGGGTCCGCATCATCGACGCCAAGGGACGCGCCGTCG
CTCAGCTGGGCGAGGCCAATCCTTCTAACGCCGACACACTGCAGCGCCCGATCAAGCTCTCGTCGCAAACGGTCGGCACG
CTGGTGCTCGTGGCCAAGCGCCCTGGCCTCGCCCAGACTCTGGCGCGTGATCTGGCGCTGACGGGCGCGCTGTTTTTCGG
CGCGGCGGGCATGGCGATCCTTCTGGCCAACAGTCTGGCCCGACGCCTGGCCCAGCCTATGGAGCGGCTCTCCGAAGCCA
TGCACGAAACCGCCGTCGGCGGACGCTTCAAGGCTCTTGAGGAGACCGCTGACGACGACGTCTTCCGCAGCCTCATCGCA
AGCTTCAACCACCTAGTGGCGCGCCTGGAATGCAATGATCAGGATCTGCGCGGCGCCATGGCCGAGCTGGTCAAAGCGCG
TGACGACGCCAACGCCGCCAACGTCCTGAAGTCGCACTTCCTGGCCAATATGAGCCACGAGATCCGCACGCCGCTCAACG
GCGTGTTGGCGATGGCCGACGTCATGGCCATGGACCAGCTCAGCGACATCCAGCGCGAGCGCCTGGCGGTGATCCGCGAG
TCAGGCGCGGTGCTTCTGGGCGTTCTGAACGACGTGCTGGACCTGTCCAAGATCGAGGCCGGCCGGCTGGAGATCCAGGA
TCGGCCCTTCGACATCGCGCAGCTGGCGCAGTCGATCCGCGAAACCTTTGTGCCCCAGGCCCGGGCCAAGGGCCTGGCCT
TCGAGGTCGGTGTCGCGCCGGAAGCTCAGGGCCTGTGGCGCGGCGACGCCGATCGCCTGCGCCAAATCCTGGGCAACCTG
ATTTCAAACGCGCTCAAGTTCACCCTGGACGGCGCGGTCGCCGTGCGCTTCGCCTCGGCCGAGGACGGCTCGGGCCTGCG
GATCGATGTCGCTGACACCGGTATCGGGATCTCGCCAGAGATTCTGCCGCGCCTGTTCGACAAGTTCGTCCAGGCTGACA
GCACGACCACGCGCCGCTTTGGAGGCTCGGGACTGGGCCTGGCCATCTGCCGCGAGCTGGCGGCGATGATGAACGGTTCG
ATCAAGGTGCAAAGCCGCGAAGGCCGAGGCTCGACCTTCACCGTGCTGGTGGGGCTACCGCGCGAGGAGACCCTGACCGA
CGTCCACTATATCGATGACGGCGATCCGATCATGGCGCCGCCCGCCGCCGAACCGCCTCGCCTCCGGGTCCTGGCGGCCG
ACGACAACCCGACCAATCAGAAGGTGGTGGCGGCGGTCTTGGCCCCGCTGAACGCCGATGTCACCCTGGTCGATGACGGC
GCGGCGTGTGTGGAGGCCTGGAAGACCGGCGACTTTGACGTCGTGCTGATGGATATCCACATGCCGGTGATGGACGGCCT
CGAGGCCGCCCGCAGCATCCGTGCGACGGAACAAGCAGAGATGCGTCGGCGCACCCCGATCATCGCGGTCACGGCGAACG
CCCTGACTCACCAGATCGAGGAGTATCTGTCCGTGGGCATGGACGGCCACGTCGCCAAGCCTATCGAGGTCAGCAAACTC
TACGACGCCATCGAGGCGGCGATGGCTGGTACGCGGCTTTCGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
AACAAAGACCTTTTCCACGCCCGCCTCCAGTTAATGAAATACTAACAAAAAAGGTAAACGAAATGTTAAAGCGAAGGCAA
CGCAAAAATGTGCGTTAGCG

Downstream 100 bases:

>100_bases
GGCTGACGATAGGCCGCTATCCAACATGAACGCAGGATAACGAGCGGCTCAGAACCGCTTCAGGCTCGCCGTGTTTCTCT
TGGCTCAACGTCGCTTACCC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MFCRATLLSDGSEALGTFRHTLAKSEVLGAMSENRNHNVSSHAPLQARIAGVALATTVLALVAACLCFMLQQWSVARQEA
RANHEVLVQMAAAGAAAPLADHNMVGVYRALEAVAKAPGVAGVRIIDAKGRAVAQLGEANPSNADTLQRPIKLSSQTVGT
LVLVAKRPGLAQTLARDLALTGALFFGAAGMAILLANSLARRLAQPMERLSEAMHETAVGGRFKALEETADDDVFRSLIA
SFNHLVARLECNDQDLRGAMAELVKARDDANAANVLKSHFLANMSHEIRTPLNGVLAMADVMAMDQLSDIQRERLAVIRE
SGAVLLGVLNDVLDLSKIEAGRLEIQDRPFDIAQLAQSIRETFVPQARAKGLAFEVGVAPEAQGLWRGDADRLRQILGNL
ISNALKFTLDGAVAVRFASAEDGSGLRIDVADTGIGISPEILPRLFDKFVQADSTTTRRFGGSGLGLAICRELAAMMNGS
IKVQSREGRGSTFTVLVGLPREETLTDVHYIDDGDPIMAPPAAEPPRLRVLAADDNPTNQKVVAAVLAPLNADVTLVDDG
AACVEAWKTGDFDVVLMDIHMPVMDGLEAARSIRATEQAEMRRRTPIIAVTANALTHQIEEYLSVGMDGHVAKPIEVSKL
YDAIEAAMAGTRLSRAA

Sequences:

>Translated_657_residues
MFCRATLLSDGSEALGTFRHTLAKSEVLGAMSENRNHNVSSHAPLQARIAGVALATTVLALVAACLCFMLQQWSVARQEA
RANHEVLVQMAAAGAAAPLADHNMVGVYRALEAVAKAPGVAGVRIIDAKGRAVAQLGEANPSNADTLQRPIKLSSQTVGT
LVLVAKRPGLAQTLARDLALTGALFFGAAGMAILLANSLARRLAQPMERLSEAMHETAVGGRFKALEETADDDVFRSLIA
SFNHLVARLECNDQDLRGAMAELVKARDDANAANVLKSHFLANMSHEIRTPLNGVLAMADVMAMDQLSDIQRERLAVIRE
SGAVLLGVLNDVLDLSKIEAGRLEIQDRPFDIAQLAQSIRETFVPQARAKGLAFEVGVAPEAQGLWRGDADRLRQILGNL
ISNALKFTLDGAVAVRFASAEDGSGLRIDVADTGIGISPEILPRLFDKFVQADSTTTRRFGGSGLGLAICRELAAMMNGS
IKVQSREGRGSTFTVLVGLPREETLTDVHYIDDGDPIMAPPAAEPPRLRVLAADDNPTNQKVVAAVLAPLNADVTLVDDG
AACVEAWKTGDFDVVLMDIHMPVMDGLEAARSIRATEQAEMRRRTPIIAVTANALTHQIEEYLSVGMDGHVAKPIEVSKL
YDAIEAAMAGTRLSRAA
>Mature_657_residues
MFCRATLLSDGSEALGTFRHTLAKSEVLGAMSENRNHNVSSHAPLQARIAGVALATTVLALVAACLCFMLQQWSVARQEA
RANHEVLVQMAAAGAAAPLADHNMVGVYRALEAVAKAPGVAGVRIIDAKGRAVAQLGEANPSNADTLQRPIKLSSQTVGT
LVLVAKRPGLAQTLARDLALTGALFFGAAGMAILLANSLARRLAQPMERLSEAMHETAVGGRFKALEETADDDVFRSLIA
SFNHLVARLECNDQDLRGAMAELVKARDDANAANVLKSHFLANMSHEIRTPLNGVLAMADVMAMDQLSDIQRERLAVIRE
SGAVLLGVLNDVLDLSKIEAGRLEIQDRPFDIAQLAQSIRETFVPQARAKGLAFEVGVAPEAQGLWRGDADRLRQILGNL
ISNALKFTLDGAVAVRFASAEDGSGLRIDVADTGIGISPEILPRLFDKFVQADSTTTRRFGGSGLGLAICRELAAMMNGS
IKVQSREGRGSTFTVLVGLPREETLTDVHYIDDGDPIMAPPAAEPPRLRVLAADDNPTNQKVVAAVLAPLNADVTLVDDG
AACVEAWKTGDFDVVLMDIHMPVMDGLEAARSIRATEQAEMRRRTPIIAVTANALTHQIEEYLSVGMDGHVAKPIEVSKL
YDAIEAAMAGTRLSRAA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=382, Percent_Identity=34.5549738219895, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1788713, Length=397, Percent_Identity=32.9974811083123, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87081816, Length=415, Percent_Identity=31.3253012048193, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=39.0041493775934, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=37.7593360995851, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=30.8035714285714, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788393, Length=302, Percent_Identity=28.476821192053, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=29.3893129770992, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=26.8292682926829, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=31.0810810810811, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=280, Percent_Identity=26.0714285714286, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=27.1111111111111, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=25.6756756756757, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=26.9387755102041, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790861, Length=245, Percent_Identity=24.8979591836735, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=195, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70033; Mature: 70033

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCRATLLSDGSEALGTFRHTLAKSEVLGAMSENRNHNVSSHAPLQARIAGVALATTVLA
CCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LVAACLCFMLQQWSVARQEARANHEVLVQMAAAGAAAPLADHNMVGVYRALEAVAKAPGV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
AGVRIIDAKGRAVAQLGEANPSNADTLQRPIKLSSQTVGTLVLVAKRPGLAQTLARDLAL
CCEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHH
TGALFFGAAGMAILLANSLARRLAQPMERLSEAMHETAVGGRFKALEETADDDVFRSLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
SFNHLVARLECNDQDLRGAMAELVKARDDANAANVLKSHFLANMSHEIRTPLNGVLAMAD
HHHHHHEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHH
VMAMDQLSDIQRERLAVIRESGAVLLGVLNDVLDLSKIEAGRLEIQDRPFDIAQLAQSIR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
ETFVPQARAKGLAFEVGVAPEAQGLWRGDADRLRQILGNLISNALKFTLDGAVAVRFASA
HHHCCHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCEEEEEEECC
EDGSGLRIDVADTGIGISPEILPRLFDKFVQADSTTTRRFGGSGLGLAICRELAAMMNGS
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
IKVQSREGRGSTFTVLVGLPREETLTDVHYIDDGDPIMAPPAAEPPRLRVLAADDNPTNQ
EEEEECCCCCCEEEEEEECCCCHHHCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCH
KVVAAVLAPLNADVTLVDDGAACVEAWKTGDFDVVLMDIHMPVMDGLEAARSIRATEQAE
HHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
MRRRTPIIAVTANALTHQIEEYLSVGMDGHVAKPIEVSKLYDAIEAAMAGTRLSRAA
HHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFCRATLLSDGSEALGTFRHTLAKSEVLGAMSENRNHNVSSHAPLQARIAGVALATTVLA
CCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LVAACLCFMLQQWSVARQEARANHEVLVQMAAAGAAAPLADHNMVGVYRALEAVAKAPGV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
AGVRIIDAKGRAVAQLGEANPSNADTLQRPIKLSSQTVGTLVLVAKRPGLAQTLARDLAL
CCEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHH
TGALFFGAAGMAILLANSLARRLAQPMERLSEAMHETAVGGRFKALEETADDDVFRSLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
SFNHLVARLECNDQDLRGAMAELVKARDDANAANVLKSHFLANMSHEIRTPLNGVLAMAD
HHHHHHEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHH
VMAMDQLSDIQRERLAVIRESGAVLLGVLNDVLDLSKIEAGRLEIQDRPFDIAQLAQSIR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
ETFVPQARAKGLAFEVGVAPEAQGLWRGDADRLRQILGNLISNALKFTLDGAVAVRFASA
HHHCCHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCEEEEEEECC
EDGSGLRIDVADTGIGISPEILPRLFDKFVQADSTTTRRFGGSGLGLAICRELAAMMNGS
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
IKVQSREGRGSTFTVLVGLPREETLTDVHYIDDGDPIMAPPAAEPPRLRVLAADDNPTNQ
EEEEECCCCCCEEEEEEECCCCHHHCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCH
KVVAAVLAPLNADVTLVDDGAACVEAWKTGDFDVVLMDIHMPVMDGLEAARSIRATEQAE
HHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
MRRRTPIIAVTANALTHQIEEYLSVGMDGHVAKPIEVSKLYDAIEAAMAGTRLSRAA
HHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA