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The map label for this gene is pyc [H]

Identifier: 16127444

GI number: 16127444

Start: 3472853

End: 3476089

Strand: Direct

Name: pyc [H]

Synonym: CC_3214

Alternate gene names: 16127444

Gene position: 3472853-3476089 (Clockwise)

Preceding gene: 16127440

Following gene: 16127449

Centisome position: 86.46

GC content: 71.76

Gene sequence:

>3237_bases
ATGTCCCTCTCCCGCGTTCTGATCGCCAACCGGGGCGAGATCGCCGTCCGGATCGCCCGCACGGCGGCCGAGGCGGGGCT
CGAGAGCGTGGCCATCTACGCCGCCGACGACGCGCAAAGCCCGCATGTCAGCGCCGCTGATCACGCCGTCGCCCTGCCGG
GCGCGGGGGCGCGGGCCTATCTCGACATCGCCGCCGTTGTCGCCGCCGCCAAGGCGCAGGGCTGCGACGCCCTGCATCCC
GGCTATGGCTTTCTGTCGGAGAACCCCCATCTCGCCCGCGCTTGCGCCGAGGCCGGGATTGTCTTCATCGGCCCTTCGCC
CGAGCACCTGACGACGTTCGGCGACAAGGCCGCCGCCCGCGCCCTGGCCGCCGAGCGCGGCCTGCCGCTGATCCCGGGAA
CCGGCGCGATCACGCTGGAGGCCGCCCGCGCCTTCCAGGCCGAGCACGGCGCGATCATGCTGAAGGCCCGGGCCGGCGGC
GGCGGACGCGGCATGCGGATGGTGCTCGACCCCGGCGAACTGGACGCCGCCTTCGCCGCCTGCGAACGCGAAGCCCTGGC
CGCGTTCGGCGACGGCGGTCTCTATGCGGAAAAGCTGATCGAGCGCGCCCGCCACATCGAGGTGCAGATCGTCGGCGACG
GCGATCAGGTGCTGGCCCTGGGCGATCGCGACTGCTCGCTGCAGCGGCGCAACCAGAAGCTGGTCGAGATCGCGCCGGCC
GCCCTCCCCGACAATCTACGCGCCGCCCTGGCCGGCTGGTCCGAGCGCCTGTGCGCCGGCTATCGCGGCCTGGCGACCGT
CGAGTTTCTGGTCGACGCCGATCCGCATTCGCCCTCGGGGGGCGAGGCCTTCTTCATCGAGGTCAACCCGCGCCTGCAGG
TCGAGCACACGGTCACCGAGGAGGTCACGGGCCTGGATCTGGTGCGCCTGCAGTTCGATCTCGCGGCGGGCAAGCGCCTG
GGCGAGCTGGAGCTGACCAACACCCCGCCGCCGTTCGGCGTGGCCATCCAGGCGCGGATCAACGCCGAGACCCTGACACC
TGAGGGTCAGGTGCGCCCGTCGACCGGGACCTTGAGCGCCTGGACGCCGCCGGGCGGCCCCGGCGTGCGCGTCGATGCGG
GCGTCGCGGCGGGGCTCACCATTGGCGCGGCCTATGACAGCCTGCTGGCCAAGGTGATCGTCCGGGGTCGGACGCCCAGC
GAAGCGGCCAGCCGGCTGGACCGCGCCTTGACCGAGCTGAAGGTCGCCGGCGTGGCGACCACCGCGCCGCTGGTCCGCGC
CATCCTGGCCCATCCGACCGCCGTGACCGGTGAGGCGACGACCACCTTCATCGCCCAGCACGCCGAGACCCTGGCCGCCG
AGGCTCAGCGCCTGACGCCCGAGACCACGGCGAGCGTCACGCGCTTCGAGGTCCTGGCGGGCGCCGAGCCTGTCGTTGCG
CCTCTGGCGGCCACGGTCGGCGCCATCACGATCCGCGAAGGCGACCTCGTCCGTCCGGGTCAGGCCCTGGCGGTGCTGGA
GGCGATGAAGATGGAGCACCTGGTCAGCGCCAGCGCCGGCGGCCGGGTGGTCAAGATCGTCGTCCAGGGCGGAGCGACCG
TCGCCGAGGGCCAGCCGCTGGTCTTCCTGGAGCCGGCGGAGGTGGAGAGCGCACTCGACGGGGAGACCGTCGAACAAGAC
CTGGACGCCCTTCGCCCGGACCTTGCCGAGGTGGTCGCCCGCCATCGCCACACCCTGGACGAGGCCCGCCCCGAGGCGGT
CGCCAAGCGGCGCAAGACCGGCCACCGCACCGCGCGCGAGAACATCGACGATCTGGTCGATCCGGGCAGCTTCCTGGAAT
ACGGCGCCCTGGCTATCGCCGCCCAGAAACGACGGCGCTCGACCGAGGACCTGATCGCCAATACGCCCGCCGACGGGCTG
ATCACCGGCATCGGAACCGTCAACGGCGCGCTGTTCCCACCCGACAAGGCGCGGACGGCGGCGCTGGCCTACGACTTCAC
GGTGCTGGCCGGGACCCAGGGGGCGATGAACCATCGCAAGTCCGACCGGCTGATGGCGCTGATCGCTGACCAGAAGCTGC
CCGTGGTCTGGTTCGCCGAGGGCGGCGGCGGGCGGCCCGGCGACACCGACACCACGGCCGTGGCGGGCCTGGACGTGCCG
ACCTTCCGCAGCTTCGCCCAGCTGTCGGGCCTGGTTCCCAAGATCGCCATCGTCGCAGGCCGCTGCTTCGCCGGCAACGC
CGCCATCGCGGGCCTTTCGGAGATCATCATCGCCACCCGCGACAGCAACCTCGGCATGGGCGGCCCGGCGATGATCGAAG
GCGGCGGGCTGGGCGTCTTCCGTCCGGAAGAGATCGGGCCGTCGGCTCATCAGTGGAAGAACGGCGTCATCGACATCCTG
GCCGACGACGAGGCCCATGCCACGCGGCTGGCCAAGCAGGCGCTGTCCTACTTCCAAGGAACGCTATCGACCTGGACCGC
ACCCGACCAGCGGCGCTTGCGCCACGCGATCCCGGAGAACCGCCTGCGCGTCTATGACGTGCGCGGCCTGATCAACCACC
TCGTCGACGAAGGCTCGTTCCTGGAGCTGCGCGGCGGCTTCGCGGCGGGGATGGTCACCGGCCTGATCCGGATCGAGGGC
CGCCCCATGGGTCTGATCGCCAATGATCCGCGCCATCTGGGCGGGGCCATCGACTGCGAGGGCGCCGAAAAGGCCGCCCG
CTTCCTGCAACTGTGCGACGCCTTCGCCCTGCCGGTCTTGAGCCTCTGCGACACGCCGGGATTCATGGTCGGGCCAGACA
GCGAGGACGCCGCCGCCGTGCGCCGGGTCAGCCGCCAGTTCATCGCCGGCGCCAAGCTGCGCTCGCCGCTGTTCACGATC
GTGACGCGCAAGGGCTATGGCCTGGGGGCTCAGGCCATGGCCGGCGGCAGCTTCCACAGCCCCGCCTTTATCGCCGCCTG
GCCCACGGGGGAGTTCGGCGGCATGGGCCTCGAAGGGGCGGTCAAGTTGGGCTACCGCAAGGAGCTGGAAGCCGAGACCG
ATCCGGTCAAACAGAAGGCGCTCTACGACCAGCTGGTCGCGCGGCTCTACGCGGCGGGCAAGGCCACCAGCATGGCGGCG
GCGCTGGAGATCGACGCGGTCATTGATCCTGCCGACACGCGGCGCTGGGTGATCGGCGGCCTGGACGCGGCGGCGGGCGT
GAGCCGGCCGTGGGAAGTGCGGGTGGACAGCTTCTGA

Upstream 100 bases:

>100_bases
TTGTTCTGATCTTCCCGGACTGGAGAGTCAAGGCTTGGAGAGTCGCGTCCAACCGGCCAAAGTGTCTCAAACGGCCGTAT
GAAGCCCTGCAGGAAGCGTC

Downstream 100 bases:

>100_bases
ACAATCCTCCCCCGCTGGGGGGAGGATTTTCCATTCTAGTCGTCCGCGTTCAGCCACTGGGTGGCGATGATCGGCCCAAG
GAAGAAGCCAATGCCCAGCG

Product: carbamoyl-phosphate synthase/carboxyl transferase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1078; Mature: 1077

Protein sequence:

>1078_residues
MSLSRVLIANRGEIAVRIARTAAEAGLESVAIYAADDAQSPHVSAADHAVALPGAGARAYLDIAAVVAAAKAQGCDALHP
GYGFLSENPHLARACAEAGIVFIGPSPEHLTTFGDKAAARALAAERGLPLIPGTGAITLEAARAFQAEHGAIMLKARAGG
GGRGMRMVLDPGELDAAFAACEREALAAFGDGGLYAEKLIERARHIEVQIVGDGDQVLALGDRDCSLQRRNQKLVEIAPA
ALPDNLRAALAGWSERLCAGYRGLATVEFLVDADPHSPSGGEAFFIEVNPRLQVEHTVTEEVTGLDLVRLQFDLAAGKRL
GELELTNTPPPFGVAIQARINAETLTPEGQVRPSTGTLSAWTPPGGPGVRVDAGVAAGLTIGAAYDSLLAKVIVRGRTPS
EAASRLDRALTELKVAGVATTAPLVRAILAHPTAVTGEATTTFIAQHAETLAAEAQRLTPETTASVTRFEVLAGAEPVVA
PLAATVGAITIREGDLVRPGQALAVLEAMKMEHLVSASAGGRVVKIVVQGGATVAEGQPLVFLEPAEVESALDGETVEQD
LDALRPDLAEVVARHRHTLDEARPEAVAKRRKTGHRTARENIDDLVDPGSFLEYGALAIAAQKRRRSTEDLIANTPADGL
ITGIGTVNGALFPPDKARTAALAYDFTVLAGTQGAMNHRKSDRLMALIADQKLPVVWFAEGGGGRPGDTDTTAVAGLDVP
TFRSFAQLSGLVPKIAIVAGRCFAGNAAIAGLSEIIIATRDSNLGMGGPAMIEGGGLGVFRPEEIGPSAHQWKNGVIDIL
ADDEAHATRLAKQALSYFQGTLSTWTAPDQRRLRHAIPENRLRVYDVRGLINHLVDEGSFLELRGGFAAGMVTGLIRIEG
RPMGLIANDPRHLGGAIDCEGAEKAARFLQLCDAFALPVLSLCDTPGFMVGPDSEDAAAVRRVSRQFIAGAKLRSPLFTI
VTRKGYGLGAQAMAGGSFHSPAFIAAWPTGEFGGMGLEGAVKLGYRKELEAETDPVKQKALYDQLVARLYAAGKATSMAA
ALEIDAVIDPADTRRWVIGGLDAAAGVSRPWEVRVDSF

Sequences:

>Translated_1078_residues
MSLSRVLIANRGEIAVRIARTAAEAGLESVAIYAADDAQSPHVSAADHAVALPGAGARAYLDIAAVVAAAKAQGCDALHP
GYGFLSENPHLARACAEAGIVFIGPSPEHLTTFGDKAAARALAAERGLPLIPGTGAITLEAARAFQAEHGAIMLKARAGG
GGRGMRMVLDPGELDAAFAACEREALAAFGDGGLYAEKLIERARHIEVQIVGDGDQVLALGDRDCSLQRRNQKLVEIAPA
ALPDNLRAALAGWSERLCAGYRGLATVEFLVDADPHSPSGGEAFFIEVNPRLQVEHTVTEEVTGLDLVRLQFDLAAGKRL
GELELTNTPPPFGVAIQARINAETLTPEGQVRPSTGTLSAWTPPGGPGVRVDAGVAAGLTIGAAYDSLLAKVIVRGRTPS
EAASRLDRALTELKVAGVATTAPLVRAILAHPTAVTGEATTTFIAQHAETLAAEAQRLTPETTASVTRFEVLAGAEPVVA
PLAATVGAITIREGDLVRPGQALAVLEAMKMEHLVSASAGGRVVKIVVQGGATVAEGQPLVFLEPAEVESALDGETVEQD
LDALRPDLAEVVARHRHTLDEARPEAVAKRRKTGHRTARENIDDLVDPGSFLEYGALAIAAQKRRRSTEDLIANTPADGL
ITGIGTVNGALFPPDKARTAALAYDFTVLAGTQGAMNHRKSDRLMALIADQKLPVVWFAEGGGGRPGDTDTTAVAGLDVP
TFRSFAQLSGLVPKIAIVAGRCFAGNAAIAGLSEIIIATRDSNLGMGGPAMIEGGGLGVFRPEEIGPSAHQWKNGVIDIL
ADDEAHATRLAKQALSYFQGTLSTWTAPDQRRLRHAIPENRLRVYDVRGLINHLVDEGSFLELRGGFAAGMVTGLIRIEG
RPMGLIANDPRHLGGAIDCEGAEKAARFLQLCDAFALPVLSLCDTPGFMVGPDSEDAAAVRRVSRQFIAGAKLRSPLFTI
VTRKGYGLGAQAMAGGSFHSPAFIAAWPTGEFGGMGLEGAVKLGYRKELEAETDPVKQKALYDQLVARLYAAGKATSMAA
ALEIDAVIDPADTRRWVIGGLDAAAGVSRPWEVRVDSF
>Mature_1077_residues
SLSRVLIANRGEIAVRIARTAAEAGLESVAIYAADDAQSPHVSAADHAVALPGAGARAYLDIAAVVAAAKAQGCDALHPG
YGFLSENPHLARACAEAGIVFIGPSPEHLTTFGDKAAARALAAERGLPLIPGTGAITLEAARAFQAEHGAIMLKARAGGG
GRGMRMVLDPGELDAAFAACEREALAAFGDGGLYAEKLIERARHIEVQIVGDGDQVLALGDRDCSLQRRNQKLVEIAPAA
LPDNLRAALAGWSERLCAGYRGLATVEFLVDADPHSPSGGEAFFIEVNPRLQVEHTVTEEVTGLDLVRLQFDLAAGKRLG
ELELTNTPPPFGVAIQARINAETLTPEGQVRPSTGTLSAWTPPGGPGVRVDAGVAAGLTIGAAYDSLLAKVIVRGRTPSE
AASRLDRALTELKVAGVATTAPLVRAILAHPTAVTGEATTTFIAQHAETLAAEAQRLTPETTASVTRFEVLAGAEPVVAP
LAATVGAITIREGDLVRPGQALAVLEAMKMEHLVSASAGGRVVKIVVQGGATVAEGQPLVFLEPAEVESALDGETVEQDL
DALRPDLAEVVARHRHTLDEARPEAVAKRRKTGHRTARENIDDLVDPGSFLEYGALAIAAQKRRRSTEDLIANTPADGLI
TGIGTVNGALFPPDKARTAALAYDFTVLAGTQGAMNHRKSDRLMALIADQKLPVVWFAEGGGGRPGDTDTTAVAGLDVPT
FRSFAQLSGLVPKIAIVAGRCFAGNAAIAGLSEIIIATRDSNLGMGGPAMIEGGGLGVFRPEEIGPSAHQWKNGVIDILA
DDEAHATRLAKQALSYFQGTLSTWTAPDQRRLRHAIPENRLRVYDVRGLINHLVDEGSFLELRGGFAAGMVTGLIRIEGR
PMGLIANDPRHLGGAIDCEGAEKAARFLQLCDAFALPVLSLCDTPGFMVGPDSEDAAAVRRVSRQFIAGAKLRSPLFTIV
TRKGYGLGAQAMAGGSFHSPAFIAAWPTGEFGGMGLEGAVKLGYRKELEAETDPVKQKALYDQLVARLYAAGKATSMAAA
LEIDAVIDPADTRRWVIGGLDAAAGVSRPWEVRVDSF

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=461, Percent_Identity=45.119305856833, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI106049295, Length=461, Percent_Identity=45.119305856833, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI106049292, Length=461, Percent_Identity=45.119305856833, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI116805327, Length=463, Percent_Identity=36.5010799136069, Blast_Score=283, Evalue=8e-76,
Organism=Homo sapiens, GI295821183, Length=457, Percent_Identity=38.7308533916849, Blast_Score=276, Evalue=1e-73,
Organism=Homo sapiens, GI65506442, Length=457, Percent_Identity=38.9496717724289, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI189095269, Length=457, Percent_Identity=38.7308533916849, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI119943100, Length=508, Percent_Identity=26.5748031496063, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI295821216, Length=521, Percent_Identity=26.295585412668, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI134142062, Length=483, Percent_Identity=29.8136645962733, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI38679960, Length=482, Percent_Identity=28.2157676348548, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI38679977, Length=482, Percent_Identity=28.2157676348548, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI38679967, Length=482, Percent_Identity=28.2157676348548, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI38679974, Length=482, Percent_Identity=28.2157676348548, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI38679971, Length=482, Percent_Identity=28.2157676348548, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI11545863, Length=542, Percent_Identity=28.9667896678967, Blast_Score=152, Evalue=2e-36,
Organism=Escherichia coli, GI1789654, Length=435, Percent_Identity=39.5402298850575, Blast_Score=273, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI17562816, Length=461, Percent_Identity=45.7700650759219, Blast_Score=332, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI71987519, Length=463, Percent_Identity=38.4449244060475, Blast_Score=292, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17567343, Length=455, Percent_Identity=36.4835164835165, Blast_Score=256, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI25147362, Length=526, Percent_Identity=27.9467680608365, Blast_Score=191, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI25147359, Length=526, Percent_Identity=27.9467680608365, Blast_Score=190, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI133931226, Length=605, Percent_Identity=27.2727272727273, Blast_Score=190, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17552936, Length=553, Percent_Identity=26.7631103074141, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71997168, Length=508, Percent_Identity=26.9685039370079, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71997163, Length=508, Percent_Identity=26.9685039370079, Blast_Score=153, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319685, Length=457, Percent_Identity=41.5754923413567, Blast_Score=310, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6319695, Length=454, Percent_Identity=42.0704845814978, Blast_Score=304, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6321376, Length=454, Percent_Identity=42.511013215859, Blast_Score=298, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6323863, Length=459, Percent_Identity=29.1938997821351, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324343, Length=488, Percent_Identity=28.2786885245902, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24652212, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24652210, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24652214, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI19921944, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24652216, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI281363050, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652224, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652222, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652220, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652218, Length=456, Percent_Identity=44.7368421052632, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24651757, Length=462, Percent_Identity=37.012987012987, Blast_Score=263, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24651759, Length=423, Percent_Identity=36.1702127659575, Blast_Score=226, Evalue=9e-59,
Organism=Drosophila melanogaster, GI161076407, Length=481, Percent_Identity=30.1455301455301, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24586460, Length=481, Percent_Identity=30.1455301455301, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI161076409, Length=482, Percent_Identity=30.2904564315353, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24586458, Length=481, Percent_Identity=30.1455301455301, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24586065, Length=556, Percent_Identity=26.7985611510791, Blast_Score=155, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 112819; Mature: 112687

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSRVLIANRGEIAVRIARTAAEAGLESVAIYAADDAQSPHVSAADHAVALPGAGARAY
CCCCEEEEECCCCEEEEEEHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHH
LDIAAVVAAAKAQGCDALHPGYGFLSENPHLARACAEAGIVFIGPSPEHLTTFGDKAAAR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCCCCHHHHCCHHHHHH
ALAAERGLPLIPGTGAITLEAARAFQAEHGAIMLKARAGGGGRGMRMVLDPGELDAAFAA
HHHHHCCCCCCCCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHH
CEREALAAFGDGGLYAEKLIERARHIEVQIVGDGDQVLALGDRDCSLQRRNQKLVEIAPA
HHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCHHHHCCCEEEECCC
ALPDNLRAALAGWSERLCAGYRGLATVEFLVDADPHSPSGGEAFFIEVNPRLQVEHTVTE
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEEHHH
EVTGLDLVRLQFDLAAGKRLGELELTNTPPPFGVAIQARINAETLTPEGQVRPSTGTLSA
HHCCCEEEEEEEEHHCCCCCCEEEECCCCCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
WTPPGGPGVRVDAGVAAGLTIGAAYDSLLAKVIVRGRTPSEAASRLDRALTELKVAGVAT
CCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHH
TAPLVRAILAHPTAVTGEATTTFIAQHAETLAAEAQRLTPETTASVTRFEVLAGAEPVVA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH
PLAATVGAITIREGDLVRPGQALAVLEAMKMEHLVSASAGGRVVKIVVQGGATVAEGQPL
HHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCE
VFLEPAEVESALDGETVEQDLDALRPDLAEVVARHRHTLDEARPEAVAKRRKTGHRTARE
EEECCHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHH
NIDDLVDPGSFLEYGALAIAAQKRRRSTEDLIANTPADGLITGIGTVNGALFPPDKARTA
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEE
ALAYDFTVLAGTQGAMNHRKSDRLMALIADQKLPVVWFAEGGGGRPGDTDTTAVAGLDVP
EEEEEEEEEECCCHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEEECCCCH
TFRSFAQLSGLVPKIAIVAGRCFAGNAAIAGLSEIIIATRDSNLGMGGPAMIEGGGLGVF
HHHHHHHHHCCCCEEHHHCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCEEECCCCCCC
RPEEIGPSAHQWKNGVIDILADDEAHATRLAKQALSYFQGTLSTWTAPDQRRLRHAIPEN
CCHHCCCCHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
RLRVYDVRGLINHLVDEGSFLELRGGFAAGMVTGLIRIEGRPMGLIANDPRHLGGAIDCE
CEEEEEHHHHHHHHHCCCCEEEECCCHHHHHHEEEEEECCCCEEEEECCHHHCCCCCCCC
GAEKAARFLQLCDAFALPVLSLCDTPGFMVGPDSEDAAAVRRVSRQFIAGAKLRSPLFTI
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCHHHCCCEEEE
VTRKGYGLGAQAMAGGSFHSPAFIAAWPTGEFGGMGLEGAVKLGYRKELEAETDPVKQKA
EEECCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHEECCCHHHCCCCCCHHHHHH
LYDQLVARLYAAGKATSMAAALEIDAVIDPADTRRWVIGGLDAAAGVSRPWEVRVDSF
HHHHHHHHHHHCCCHHHHHEEEEEEEEECCCCCCEEEEECCCHHCCCCCCCEEEECCC
>Mature Secondary Structure 
SLSRVLIANRGEIAVRIARTAAEAGLESVAIYAADDAQSPHVSAADHAVALPGAGARAY
CCCEEEEECCCCEEEEEEHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHH
LDIAAVVAAAKAQGCDALHPGYGFLSENPHLARACAEAGIVFIGPSPEHLTTFGDKAAAR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCCCCHHHHCCHHHHHH
ALAAERGLPLIPGTGAITLEAARAFQAEHGAIMLKARAGGGGRGMRMVLDPGELDAAFAA
HHHHHCCCCCCCCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHH
CEREALAAFGDGGLYAEKLIERARHIEVQIVGDGDQVLALGDRDCSLQRRNQKLVEIAPA
HHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCHHHHCCCEEEECCC
ALPDNLRAALAGWSERLCAGYRGLATVEFLVDADPHSPSGGEAFFIEVNPRLQVEHTVTE
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEEHHH
EVTGLDLVRLQFDLAAGKRLGELELTNTPPPFGVAIQARINAETLTPEGQVRPSTGTLSA
HHCCCEEEEEEEEHHCCCCCCEEEECCCCCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
WTPPGGPGVRVDAGVAAGLTIGAAYDSLLAKVIVRGRTPSEAASRLDRALTELKVAGVAT
CCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHH
TAPLVRAILAHPTAVTGEATTTFIAQHAETLAAEAQRLTPETTASVTRFEVLAGAEPVVA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH
PLAATVGAITIREGDLVRPGQALAVLEAMKMEHLVSASAGGRVVKIVVQGGATVAEGQPL
HHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCE
VFLEPAEVESALDGETVEQDLDALRPDLAEVVARHRHTLDEARPEAVAKRRKTGHRTARE
EEECCHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHH
NIDDLVDPGSFLEYGALAIAAQKRRRSTEDLIANTPADGLITGIGTVNGALFPPDKARTA
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEE
ALAYDFTVLAGTQGAMNHRKSDRLMALIADQKLPVVWFAEGGGGRPGDTDTTAVAGLDVP
EEEEEEEEEECCCHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEEECCCCH
TFRSFAQLSGLVPKIAIVAGRCFAGNAAIAGLSEIIIATRDSNLGMGGPAMIEGGGLGVF
HHHHHHHHHCCCCEEHHHCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCEEECCCCCCC
RPEEIGPSAHQWKNGVIDILADDEAHATRLAKQALSYFQGTLSTWTAPDQRRLRHAIPEN
CCHHCCCCHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
RLRVYDVRGLINHLVDEGSFLELRGGFAAGMVTGLIRIEGRPMGLIANDPRHLGGAIDCE
CEEEEEHHHHHHHHHCCCCEEEECCCHHHHHHEEEEEECCCCEEEEECCHHHCCCCCCCC
GAEKAARFLQLCDAFALPVLSLCDTPGFMVGPDSEDAAAVRRVSRQFIAGAKLRSPLFTI
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCHHHCCCEEEE
VTRKGYGLGAQAMAGGSFHSPAFIAAWPTGEFGGMGLEGAVKLGYRKELEAETDPVKQKA
EEECCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHEECCCHHHCCCCCCHHHHHH
LYDQLVARLYAAGKATSMAAALEIDAVIDPADTRRWVIGGLDAAAGVSRPWEVRVDSF
HHHHHHHHHHHCCCHHHHHEEEEEEEEECCCCCCEEEEECCCHHCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]