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The map label for this gene is pleC [H]

Identifier: 16127116

GI number: 16127116

Start: 3106899

End: 3108377

Strand: Direct

Name: pleC [H]

Synonym: CC_2884

Alternate gene names: 16127116

Gene position: 3106899-3108377 (Clockwise)

Preceding gene: 16127115

Following gene: 16127119

Centisome position: 77.34

GC content: 67.41

Gene sequence:

>1479_bases
ATGCAGGCGGCTGGAGGGTACGTTTTCGTCTTCACGCTGATGGGCGTTGCGCCCGTCGCCCTCAGCGCGCCCGCGTTTCT
GACCCTCTATCGCTACAATGCCGGCGCGCCGCACTTCCGAGACTGGGGCGTGGCCTACGCCGCCCTGACCGGAGCGATCG
GGTTTGGCGCGCTCAGCCTCTGGGAGCCCGGCCCGGTCCTCCTGCCGGTAGTGGCCAGCCAGACCCTGTCACTGGTGTGT
CTGGGCCTGTTCTACTATTTCCATGCCGTCGGGAGCCTTCGTTATGTGAAGGCGGCGATGGTCGAGTCGCTGGCCGCCAT
GGTCTCGGTCGCCGCCCTGGCCCTGATCGTCATCTTCAACGCCGTGTCCCCCGACTACGGTCTGATGATGTCGTCGATCG
TCCAGCTGCTGGTCTATTTCTGGGAAGGCGCGATCCTGCGCCGCGAAGGCCTGCTGGGTCGCGCCTTCTTCTACGCCTGT
ATCGGCCGGGGCCTGCTGTCGGTCTGGCGCCCTTTGGCCATCGCGGACTTCGACAGCCTGTTCCTGTACACCACCCTGGC
CCTGGCCTTAACCTCGGCCTCGACCCTGCTGGTCATGTTGCTGGCGATCGAGCGCGAGCATGGCCAGCTGGAGGCCGCCA
ACCAGCGCCTGATCCTGCAGAACGCCCTGATCGGCCGCCAGGCGGCGACGCTGCAGCAGGTGGCGGTGGACCTCAGCCGC
GAGCAGCTGCGCGCCGCCCAGGCGGAGAACGCCCGTCGCGACTTTCTCAGCGGGATCAATCACGAGTTCCGCACGCCCCT
GAACGCGGTGCTGGGCTTCGCCTCGGTCATCATGGGCGCCAAGAACACGCCCGCCAATGTGCGGCAGTTCGCCGGCGGCA
TCCACGAGGCCGGCGAGCGCATCCTAGCGCACTTCGAACAGATCCAGACCGTCAAGGCGCTGGAGCAGGCGCCGGCATGG
ACGCCGGAAGCCATTGAGGTTCCTGACCTCCTGGCCTCGATCAGAACCTTCGCCGAGAACCATCCGCTGGCGGACGGAAT
CGATCTGCGGATCGAGGACAGCGGCGAGGTGCTGGCCGTCCATGCCGATCGCGCCAATCTGGAGAACGCCTTGCGCCAGA
TCGTGGACAATGCGGTGCTCTACACGCCGCCGGGCCAGCCGGTCATCGTCGCCTGCCGACGGGGCGCGGCCGACGCGGCC
GTCATCGAGGTGATGGATCGCGGGCCGGGCTTTGACCCCAATGTCGACTTTGAAAAGCCCGTGCCGTTCACGCGGGGCAG
CTCCCATGCGGGCCTGAACAAGCCGGGCCTGGGCCTTGGCCTGTTCATCGCCCGCAACCTGCTGGAAGCCAGCGGGGTGA
CGCTGGAGCGGCGCGATCATCCCGAGGGCGGGACGATCATCACCCTGGCCCTGCCGGCGGCCATCGCCGAAGCGCCGCCA
GACAAGCCGGCCAGGACGTCACGCAAAAAGACCGCCTGA

Upstream 100 bases:

>100_bases
TCACCGTGTGACGATTGATCTTCCCCCCACGCCCCGGCGGCGATAGGGTTTCCGTCACGGGGGCTCGCAGGGTGAGACGG
CCGCCGGGAGGGCGAACTCC

Downstream 100 bases:

>100_bases
CGTTCCAAGCCTCTGAAACAACGCTTTTTCCGATCGGATCGGTGGGTCAGGCGAGAGCAGAGCCTAGAGCCCCGCACACA
CCCCGCAGAACGCCGCGATA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MQAAGGYVFVFTLMGVAPVALSAPAFLTLYRYNAGAPHFRDWGVAYAALTGAIGFGALSLWEPGPVLLPVVASQTLSLVC
LGLFYYFHAVGSLRYVKAAMVESLAAMVSVAALALIVIFNAVSPDYGLMMSSIVQLLVYFWEGAILRREGLLGRAFFYAC
IGRGLLSVWRPLAIADFDSLFLYTTLALALTSASTLLVMLLAIEREHGQLEAANQRLILQNALIGRQAATLQQVAVDLSR
EQLRAAQAENARRDFLSGINHEFRTPLNAVLGFASVIMGAKNTPANVRQFAGGIHEAGERILAHFEQIQTVKALEQAPAW
TPEAIEVPDLLASIRTFAENHPLADGIDLRIEDSGEVLAVHADRANLENALRQIVDNAVLYTPPGQPVIVACRRGAADAA
VIEVMDRGPGFDPNVDFEKPVPFTRGSSHAGLNKPGLGLGLFIARNLLEASGVTLERRDHPEGGTIITLALPAAIAEAPP
DKPARTSRKKTA

Sequences:

>Translated_492_residues
MQAAGGYVFVFTLMGVAPVALSAPAFLTLYRYNAGAPHFRDWGVAYAALTGAIGFGALSLWEPGPVLLPVVASQTLSLVC
LGLFYYFHAVGSLRYVKAAMVESLAAMVSVAALALIVIFNAVSPDYGLMMSSIVQLLVYFWEGAILRREGLLGRAFFYAC
IGRGLLSVWRPLAIADFDSLFLYTTLALALTSASTLLVMLLAIEREHGQLEAANQRLILQNALIGRQAATLQQVAVDLSR
EQLRAAQAENARRDFLSGINHEFRTPLNAVLGFASVIMGAKNTPANVRQFAGGIHEAGERILAHFEQIQTVKALEQAPAW
TPEAIEVPDLLASIRTFAENHPLADGIDLRIEDSGEVLAVHADRANLENALRQIVDNAVLYTPPGQPVIVACRRGAADAA
VIEVMDRGPGFDPNVDFEKPVPFTRGSSHAGLNKPGLGLGLFIARNLLEASGVTLERRDHPEGGTIITLALPAAIAEAPP
DKPARTSRKKTA
>Mature_492_residues
MQAAGGYVFVFTLMGVAPVALSAPAFLTLYRYNAGAPHFRDWGVAYAALTGAIGFGALSLWEPGPVLLPVVASQTLSLVC
LGLFYYFHAVGSLRYVKAAMVESLAAMVSVAALALIVIFNAVSPDYGLMMSSIVQLLVYFWEGAILRREGLLGRAFFYAC
IGRGLLSVWRPLAIADFDSLFLYTTLALALTSASTLLVMLLAIEREHGQLEAANQRLILQNALIGRQAATLQQVAVDLSR
EQLRAAQAENARRDFLSGINHEFRTPLNAVLGFASVIMGAKNTPANVRQFAGGIHEAGERILAHFEQIQTVKALEQAPAW
TPEAIEVPDLLASIRTFAENHPLADGIDLRIEDSGEVLAVHADRANLENALRQIVDNAVLYTPPGQPVIVACRRGAADAA
VIEVMDRGPGFDPNVDFEKPVPFTRGSSHAGLNKPGLGLGLFIARNLLEASGVTLERRDHPEGGTIITLALPAAIAEAPP
DKPARTSRKKTA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=266, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=26.8199233716475, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=26.4227642276423, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=26, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=26.5560165975104, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52781; Mature: 52781

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAAGGYVFVFTLMGVAPVALSAPAFLTLYRYNAGAPHFRDWGVAYAALTGAIGFGALSL
CCCCCCHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
WEPGPVLLPVVASQTLSLVCLGLFYYFHAVGSLRYVKAAMVESLAAMVSVAALALIVIFN
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSPDYGLMMSSIVQLLVYFWEGAILRREGLLGRAFFYACIGRGLLSVWRPLAIADFDSL
CCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FLYTTLALALTSASTLLVMLLAIEREHGQLEAANQRLILQNALIGRQAATLQQVAVDLSR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQLRAAQAENARRDFLSGINHEFRTPLNAVLGFASVIMGAKNTPANVRQFAGGIHEAGER
HHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHH
ILAHFEQIQTVKALEQAPAWTPEAIEVPDLLASIRTFAENHPLADGIDLRIEDSGEVLAV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEE
HADRANLENALRQIVDNAVLYTPPGQPVIVACRRGAADAAVIEVMDRGPGFDPNVDFEKP
ECCHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
VPFTRGSSHAGLNKPGLGLGLFIARNLLEASGVTLERRDHPEGGTIITLALPAAIAEAPP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEECHHHHHCCCC
DKPARTSRKKTA
CCCCCCCCCCCC
>Mature Secondary Structure
MQAAGGYVFVFTLMGVAPVALSAPAFLTLYRYNAGAPHFRDWGVAYAALTGAIGFGALSL
CCCCCCHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
WEPGPVLLPVVASQTLSLVCLGLFYYFHAVGSLRYVKAAMVESLAAMVSVAALALIVIFN
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSPDYGLMMSSIVQLLVYFWEGAILRREGLLGRAFFYACIGRGLLSVWRPLAIADFDSL
CCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FLYTTLALALTSASTLLVMLLAIEREHGQLEAANQRLILQNALIGRQAATLQQVAVDLSR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQLRAAQAENARRDFLSGINHEFRTPLNAVLGFASVIMGAKNTPANVRQFAGGIHEAGER
HHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHH
ILAHFEQIQTVKALEQAPAWTPEAIEVPDLLASIRTFAENHPLADGIDLRIEDSGEVLAV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEE
HADRANLENALRQIVDNAVLYTPPGQPVIVACRRGAADAAVIEVMDRGPGFDPNVDFEKP
ECCHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
VPFTRGSSHAGLNKPGLGLGLFIARNLLEASGVTLERRDHPEGGTIITLALPAAIAEAPP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEECHHHHHCCCC
DKPARTSRKKTA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]