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The map label for this gene is blh [H]

Identifier: 16127098

GI number: 16127098

Start: 3090193

End: 3090996

Strand: Direct

Name: blh [H]

Synonym: CC_2866

Alternate gene names: 16127098

Gene position: 3090193-3090996 (Clockwise)

Preceding gene: 16127097

Following gene: 16127099

Centisome position: 76.93

GC content: 70.77

Gene sequence:

>804_bases
GTGGTTGATCCGGCCACCAAGACCGCCGCGATCATCGATCCGGTGCTGGATTTCGAGCCCAAGGCGGGCAAGCTCTCCAC
CACCTCGGCCGACGCCCTGCTGGCGGCCGTGCGCGACCAGGGCCTGCATCTGGCCTATGTGCTGGAGACCCACGCCCACG
CCGATCACCTGTCGGCCGCCGACCTGATCCGCCGCAAGACCGGCGCGAAGATCGTCATCGGCGCCAAGATCACCGAGGTC
CAGAAGACCTTCATTCCCGTGTTCGAGTCCGACGCCCGCCCCGACGGCGCGGTGTTCGACGTGCTGATGGAGGAAGGCGA
CGCCCTGCCGCTGGGCGAGCTGTCGATCGCGGCGCTGCACACGCCGGGCCATACGCCGGCCTGCATGACCTACCGGATCG
GCGACGCCGCCTTTGTCGGCGACACCCTGTTCATGCCCGACTACGGCACCGCCCGCGCCGATTTCCCCGGCGGCGACGCG
CGCACGCTGTATCGCTCGATCCAGAAGGTGCTGGCCCTGCCCGACGAGACCCGGATCTTCGTCGGCCACGACTATCTGCC
CGCCGGCCGCGACACGTTCCACTGGGAGACGACGGTGGCCGAGGAGCGGGCCCGCAACATCCATGTGGGCGGCGGCGCCC
AGGAGGACGACTTCGTGGCCATGCGCCAGGCCCGCGACGCCACCCTGGCCGCCCCGACCCTGATCCTGCCCTCGCTGCAG
GTGAACATCCGCGCCGGCGCCCTGCCCGACCCGACGGCGGCGGGGAACGTCTTCCTGCGCCTGCCGGTGACCTGGGCGGC
TTAG

Upstream 100 bases:

>100_bases
GCAAGTCCTTATATGAAGGCCGTGCTGCAGAAAGGCTCTGACCATGCGACCCGACGTTCAAGCGTTTTTCGACACCGCGA
CCTTCACCGCCAGCTATCTG

Downstream 100 bases:

>100_bases
GGTAGGCGGAGGTCGAGTTCGTGGATTATCCCTGAGCGCCGCTGGGGCTCAGAACAGGAGGCGACCGATGAGCATGGACA
TCGCTGACGGCAACGATCCC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MVDPATKTAAIIDPVLDFEPKAGKLSTTSADALLAAVRDQGLHLAYVLETHAHADHLSAADLIRRKTGAKIVIGAKITEV
QKTFIPVFESDARPDGAVFDVLMEEGDALPLGELSIAALHTPGHTPACMTYRIGDAAFVGDTLFMPDYGTARADFPGGDA
RTLYRSIQKVLALPDETRIFVGHDYLPAGRDTFHWETTVAEERARNIHVGGGAQEDDFVAMRQARDATLAAPTLILPSLQ
VNIRAGALPDPTAAGNVFLRLPVTWAA

Sequences:

>Translated_267_residues
MVDPATKTAAIIDPVLDFEPKAGKLSTTSADALLAAVRDQGLHLAYVLETHAHADHLSAADLIRRKTGAKIVIGAKITEV
QKTFIPVFESDARPDGAVFDVLMEEGDALPLGELSIAALHTPGHTPACMTYRIGDAAFVGDTLFMPDYGTARADFPGGDA
RTLYRSIQKVLALPDETRIFVGHDYLPAGRDTFHWETTVAEERARNIHVGGGAQEDDFVAMRQARDATLAAPTLILPSLQ
VNIRAGALPDPTAAGNVFLRLPVTWAA
>Mature_267_residues
MVDPATKTAAIIDPVLDFEPKAGKLSTTSADALLAAVRDQGLHLAYVLETHAHADHLSAADLIRRKTGAKIVIGAKITEV
QKTFIPVFESDARPDGAVFDVLMEEGDALPLGELSIAALHTPGHTPACMTYRIGDAAFVGDTLFMPDYGTARADFPGGDA
RTLYRSIQKVLALPDETRIFVGHDYLPAGRDTFHWETTVAEERARNIHVGGGAQEDDFVAMRQARDATLAAPTLILPSLQ
VNIRAGALPDPTAAGNVFLRLPVTWAA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=257, Percent_Identity=31.9066147859922, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1787158, Length=209, Percent_Identity=29.6650717703349, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=245, Percent_Identity=29.7959183673469, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI221330176, Length=254, Percent_Identity=33.0708661417323, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356335, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667703, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667711, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 28573; Mature: 28573

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDPATKTAAIIDPVLDFEPKAGKLSTTSADALLAAVRDQGLHLAYVLETHAHADHLSAA
CCCCCCCHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
DLIRRKTGAKIVIGAKITEVQKTFIPVFESDARPDGAVFDVLMEEGDALPLGELSIAALH
HHHHHHCCCEEEEECCHHHHHHHHCCEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEE
TPGHTPACMTYRIGDAAFVGDTLFMPDYGTARADFPGGDARTLYRSIQKVLALPDETRIF
CCCCCCEEEEEECCCEEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
VGHDYLPAGRDTFHWETTVAEERARNIHVGGGAQEDDFVAMRQARDATLAAPTLILPSLQ
EECCCCCCCCCCEEEEHHHHHHHHCEEEECCCCCCCHHHHHHHHCCCHHCCCEEEECCEE
VNIRAGALPDPTAAGNVFLRLPVTWAA
EEEEECCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MVDPATKTAAIIDPVLDFEPKAGKLSTTSADALLAAVRDQGLHLAYVLETHAHADHLSAA
CCCCCCCHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
DLIRRKTGAKIVIGAKITEVQKTFIPVFESDARPDGAVFDVLMEEGDALPLGELSIAALH
HHHHHHCCCEEEEECCHHHHHHHHCCEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEE
TPGHTPACMTYRIGDAAFVGDTLFMPDYGTARADFPGGDARTLYRSIQKVLALPDETRIF
CCCCCCEEEEEECCCEEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
VGHDYLPAGRDTFHWETTVAEERARNIHVGGGAQEDDFVAMRQARDATLAAPTLILPSLQ
EECCCCCCCCCCEEEEHHHHHHHHCEEEECCCCCCCHHHHHHHHCCCHHCCCEEEECCEE
VNIRAGALPDPTAAGNVFLRLPVTWAA
EEEEECCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]