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The map label for this gene is rutD

Identifier: 16127029

GI number: 16127029

Start: 3009237

End: 3010046

Strand: Direct

Name: rutD

Synonym: CC_2797

Alternate gene names: 16127029

Gene position: 3009237-3010046 (Clockwise)

Preceding gene: 16127028

Following gene: 16127030

Centisome position: 74.91

GC content: 68.89

Gene sequence:

>810_bases
GTGCGTCGCATGACCATCGGAACCGTCGACGGCCTGCACTACGAACTCCACGGCGGCCCAATCGCCGGGCGCGAGGTCGT
GTTGTTGTCGTCGGGCCTGGGCGGCTCGGGCGCGTTCTGGGCGCCGCAGATGCAGGCCCTGACCCAGCGCTGGCCGGTGG
TCACCTATGACCATCGCGGCACGGGCCGTAGCGTTCGCGAACTGCCGCCCCGCTACACGCTCGCCCACATGGCCGATGAC
ATGGTCAAGGTCATGGACGCCCTGGGCCTGGCCAAGGCCCATGTGGTCGGCCACGCGGCGGGCGGCAATGCGGGGCTGCA
ACTGGCGCTGGACCATCCGGATCGCCTGGCAAAGCTGGTGGTGGTCAACGGCTGGAGCCGGCCTGATCCGCACATCCGGC
GCTGCTTCGACACCCGCCTCCACCTGCTGAACGACACGGGCCCCGAGGCCTATGTCCACGCCCAGCCGATCTTCCTCTAT
CCGGCCGACTGGATCTCGCGGAACCACACCCGGCTGATGGCCGAGGAGGCCCACCATGTGGCCGCCTTCCCGCCACGCGA
GGTGATGCTGGCCAGGATCAACGCTCTGCTGGCCTTCGACATCGACGCGCGGCTGGAAGACATCACCCACCGGGTGCTGA
TCAGCGCCAGCGCCGACGACATGCTGGTGCCGATGAGCTGCTCCCAGCGCCTGGCCGGCCGCCTGCCCAACGCCGACTTC
CAGCAGGTCGCCTGGGGCGGGCACGGCTTCACCGTCACCGATCCGGAGACCTTCAACGAGGCTCTGGTGAGTTTTCTGGA
GGGGGCGTGA

Upstream 100 bases:

>100_bases
ATCCGCTGGCGTCTCACGTGTCCGCTGAACCAGGGGTTCCCGCCACAAGGGCGGGAATGACGGAGGTTTTGGCTATGAAA
CGCGTCCGCAGTCACAAGCG

Downstream 100 bases:

>100_bases
TGAAGCGTCCTCAAATCCTCCCCCCAGCGGGGGAGGTGGCGCGAAGCGCCGGAGGGGGAAGTGCTGCTGCCCCTGCCGCT
TCCCCCTCCGTCGTCTCTTC

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Aminohydrolase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRGTGRSVRELPPRYTLAHMADD
MVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLVVVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLY
PADWISRNHTRLMAEEAHHVAAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADF
QQVAWGGHGFTVTDPETFNEALVSFLEGA

Sequences:

>Translated_269_residues
MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRGTGRSVRELPPRYTLAHMADD
MVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLVVVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLY
PADWISRNHTRLMAEEAHHVAAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADF
QQVAWGGHGFTVTDPETFNEALVSFLEGA
>Mature_269_residues
MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRGTGRSVRELPPRYTLAHMADD
MVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLVVVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLY
PADWISRNHTRLMAEEAHHVAAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADF
QQVAWGGHGFTVTDPETFNEALVSFLEGA

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family

Homologues:

Organism=Escherichia coli, GI1787244, Length=240, Percent_Identity=45.4166666666667, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUTD_CAUCN (B8H1Q3)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002518260.1
- ProteinModelPortal:   B8H1Q3
- SMR:   B8H1Q3
- GeneID:   7331317
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_02887
- ProtClustDB:   CLSK891155
- HAMAP:   MF_00832
- InterPro:   IPR000073
- InterPro:   IPR019913
- PRINTS:   PR00111
- TIGRFAMs:   TIGR03611

Pfam domain/function: PF00561 Abhydrolase_1

EC number: NA

Molecular weight: Translated: 29553; Mature: 29553

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRG
CCCEEEEEECCEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCEEEECCCC
TGRSVRELPPRYTLAHMADDMVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLV
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCEEEEE
VVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLYPADWISRNHTRLMAEEAHHV
EEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECHHHHCCCCHHHHHHHCCCC
AAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADF
CCCCHHHHHHHHHHHHEEECCCHHHHHHHEEEEEECCCCCEEECCCHHHHHHHCCCCCCH
QQVAWGGHGFTVTDPETFNEALVSFLEGA
HHHEECCCCEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRG
CCCEEEEEECCEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCEEEECCCC
TGRSVRELPPRYTLAHMADDMVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLV
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCEEEEE
VVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLYPADWISRNHTRLMAEEAHHV
EEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECHHHHCCCCHHHHHHHCCCC
AAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADF
CCCCHHHHHHHHHHHHEEECCCHHHHHHHEEEEEECCCCCEEECCCHHHHHHHCCCCCCH
QQVAWGGHGFTVTDPETFNEALVSFLEGA
HHHEECCCCEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA