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The map label for this gene is exuT [H]

Identifier: 16126724

GI number: 16126724

Start: 2695323

End: 2696657

Strand: Direct

Name: exuT [H]

Synonym: CC_2485

Alternate gene names: 16126724

Gene position: 2695323-2696657 (Clockwise)

Preceding gene: 16126722

Following gene: 16126725

Centisome position: 67.1

GC content: 67.87

Gene sequence:

>1335_bases
ATGGCGCAACCCGCCACGCCGTCGCCCGTTATCGCCCCGGTGTCGACGGCCTATCGCCGCTACGCCCTCTGGGTGCTGCT
GATCATCTACACGCTGAACTTCCTGGATCGGCAGGTGGTCAACATCCTGGCCGAGCCGATCAAACGCGATCTGGGCTTGG
CCGACTGGCAGCTGGGCATGATGACGGGCCTGGCCTTTGCGATCTTCTACACCGTGCTGGGCATTCCGATCGCCCGGATG
GCCGAGACCAAGAACCGCCCCTACATCATCGGCATCTCGGTCGCGGTCTGGAGCGCCTTTACGGTGGTCTGCGGCTTCGC
CCAGAACTTCTGGCAACTGATCCTGGCCCGGATCGGCGTGGGCGTCGGCGAGGCCGGCTGCACCCCGCCGGCCCACTCGC
TGATCAGCGACTATGTGCCCAAGGAAAAGCGGGCCAGCGCCATCGCCTTCTATTCGATCGGCACGCCGCTGGGCACCCTG
GCCGGCATGGCGATGGGCGGACTGGTGGCCGACGCCTATGGCTGGCGGGTGGCCTTCATGGTCGCCGGCGCGCCGGGCCT
GTTGTTCGCGCTGATCGCCGCCTTCACCCTGGTGGAACCGCGCAAGAAGCTGGCCGCCGAAATGGCCGCCCGCGCCAGCA
CCCAGATCAGCTTCGCCGCGGCGCTCGCGGTGCTGGCCACCAAGAAGACCTTCTGGCTGGTGGCGCTGGCCGCCTCGATC
AAGGCCTTCATCGGCTATGGCTACGCACCGTTCATCGCCTCATTCTTCTTCCGCGTGCACGGCCCCGAAATCGCCCAGCT
CGCCGGGACGTTCGGCCTGAAGTCGGCCGGCTTTCTGGGTCTGGCGCTGGGCCTGATCAACGGCACGGCTGGGGTGATCG
GCGCCTGGCTGGGCGGCGTCCTGGCCGACCGCCTGGGGGCCAAGGACCTGCGCGCCTATGTCACGGTGCCGGCCATCGCC
TCGGTGGTGACCATCCCGATCTTTGTCGTCGCCATGAGTCTCGACGCGCCGATGGCCGCCATTGGCCTTCTGTCCGTGAA
CGCCCTGCTGGCCACCCTGTGGTACGGCCCGGTCTACGCGACGGCCCAGAGCATCGTCGATCCGGCCCTGCGCGCCACAG
CCTCGGCCGTGCTGCTGCTGATCATCAACCTGATCGGCCTGGGCTTTGGCCCGCTGATCGTGGGCCTGCTCAGCGACATC
CTGGCCGGACCGGTGGGACTGGGTGAGGCTCAGGGCGTGCGCTGGGCCCTGATCATTTCGGCCACCCTGGGGCTGGGCGC
GTTCGCCCTGTTCTGGGCAGCCCGCAAGACCATCCGCGACGAGATGGTCAGCTAA

Upstream 100 bases:

>100_bases
TCCTGAAAGCTGTTTCGAAAATGCCGGATGGCGTTCCGGCTTAGCCTGCGTTTATGGTGCGCTCAACGATTAGAACAAAT
GTTCGAGGGAGAGAGAGTCC

Downstream 100 bases:

>100_bases
CAGAAAATCCTCCCCCAAGCGGGGGAGGTGTCGGCTCGAAGAGACGACGGAGGGGGAAGCGGCAGGTTCAACAGAACTTC
CCCCTCCGGCCTTCGGCCAC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAQPATPSPVIAPVSTAYRRYALWVLLIIYTLNFLDRQVVNILAEPIKRDLGLADWQLGMMTGLAFAIFYTVLGIPIARM
AETKNRPYIIGISVAVWSAFTVVCGFAQNFWQLILARIGVGVGEAGCTPPAHSLISDYVPKEKRASAIAFYSIGTPLGTL
AGMAMGGLVADAYGWRVAFMVAGAPGLLFALIAAFTLVEPRKKLAAEMAARASTQISFAAALAVLATKKTFWLVALAASI
KAFIGYGYAPFIASFFFRVHGPEIAQLAGTFGLKSAGFLGLALGLINGTAGVIGAWLGGVLADRLGAKDLRAYVTVPAIA
SVVTIPIFVVAMSLDAPMAAIGLLSVNALLATLWYGPVYATAQSIVDPALRATASAVLLLIINLIGLGFGPLIVGLLSDI
LAGPVGLGEAQGVRWALIISATLGLGAFALFWAARKTIRDEMVS

Sequences:

>Translated_444_residues
MAQPATPSPVIAPVSTAYRRYALWVLLIIYTLNFLDRQVVNILAEPIKRDLGLADWQLGMMTGLAFAIFYTVLGIPIARM
AETKNRPYIIGISVAVWSAFTVVCGFAQNFWQLILARIGVGVGEAGCTPPAHSLISDYVPKEKRASAIAFYSIGTPLGTL
AGMAMGGLVADAYGWRVAFMVAGAPGLLFALIAAFTLVEPRKKLAAEMAARASTQISFAAALAVLATKKTFWLVALAASI
KAFIGYGYAPFIASFFFRVHGPEIAQLAGTFGLKSAGFLGLALGLINGTAGVIGAWLGGVLADRLGAKDLRAYVTVPAIA
SVVTIPIFVVAMSLDAPMAAIGLLSVNALLATLWYGPVYATAQSIVDPALRATASAVLLLIINLIGLGFGPLIVGLLSDI
LAGPVGLGEAQGVRWALIISATLGLGAFALFWAARKTIRDEMVS
>Mature_443_residues
AQPATPSPVIAPVSTAYRRYALWVLLIIYTLNFLDRQVVNILAEPIKRDLGLADWQLGMMTGLAFAIFYTVLGIPIARMA
ETKNRPYIIGISVAVWSAFTVVCGFAQNFWQLILARIGVGVGEAGCTPPAHSLISDYVPKEKRASAIAFYSIGTPLGTLA
GMAMGGLVADAYGWRVAFMVAGAPGLLFALIAAFTLVEPRKKLAAEMAARASTQISFAAALAVLATKKTFWLVALAASIK
AFIGYGYAPFIASFFFRVHGPEIAQLAGTFGLKSAGFLGLALGLINGTAGVIGAWLGGVLADRLGAKDLRAYVTVPAIAS
VVTIPIFVVAMSLDAPMAAIGLLSVNALLATLWYGPVYATAQSIVDPALRATASAVLLLIINLIGLGFGPLIVGLLSDIL
AGPVGLGEAQGVRWALIISATLGLGAFALFWAARKTIRDEMVS

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=412, Percent_Identity=26.9417475728155, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI14042968, Length=412, Percent_Identity=26.9417475728155, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI215490100, Length=402, Percent_Identity=26.3681592039801, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI185136021, Length=378, Percent_Identity=24.6031746031746, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI215490102, Length=408, Percent_Identity=23.7745098039216, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367379, Length=293, Percent_Identity=24.5733788395904, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082320, Length=185, Percent_Identity=26.4864864864865, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17557872, Length=407, Percent_Identity=23.0958230958231, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193209775, Length=400, Percent_Identity=25.5, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539092, Length=406, Percent_Identity=23.6453201970443, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71992409, Length=447, Percent_Identity=25.2796420581655, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24640209, Length=353, Percent_Identity=25.7790368271955, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654037, Length=411, Percent_Identity=22.1411192214112, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654041, Length=411, Percent_Identity=22.1411192214112, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654039, Length=409, Percent_Identity=22.4938875305623, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864456, Length=409, Percent_Identity=22.4938875305623, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654044, Length=260, Percent_Identity=21.9230769230769, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46520; Mature: 46389

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPATPSPVIAPVSTAYRRYALWVLLIIYTLNFLDRQVVNILAEPIKRDLGLADWQLGM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MTGLAFAIFYTVLGIPIARMAETKNRPYIIGISVAVWSAFTVVCGFAQNFWQLILARIGV
HHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVGEAGCTPPAHSLISDYVPKEKRASAIAFYSIGTPLGTLAGMAMGGLVADAYGWRVAFM
CCCCCCCCCCHHHHHHHCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEE
VAGAPGLLFALIAAFTLVEPRKKLAAEMAARASTQISFAAALAVLATKKTFWLVALAASI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAFIGYGYAPFIASFFFRVHGPEIAQLAGTFGLKSAGFLGLALGLINGTAGVIGAWLGGV
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
LADRLGAKDLRAYVTVPAIASVVTIPIFVVAMSLDAPMAAIGLLSVNALLATLWYGPVYA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAQSIVDPALRATASAVLLLIINLIGLGFGPLIVGLLSDILAGPVGLGEAQGVRWALIIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHH
ATLGLGAFALFWAARKTIRDEMVS
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQPATPSPVIAPVSTAYRRYALWVLLIIYTLNFLDRQVVNILAEPIKRDLGLADWQLGM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MTGLAFAIFYTVLGIPIARMAETKNRPYIIGISVAVWSAFTVVCGFAQNFWQLILARIGV
HHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVGEAGCTPPAHSLISDYVPKEKRASAIAFYSIGTPLGTLAGMAMGGLVADAYGWRVAFM
CCCCCCCCCCHHHHHHHCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEE
VAGAPGLLFALIAAFTLVEPRKKLAAEMAARASTQISFAAALAVLATKKTFWLVALAASI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAFIGYGYAPFIASFFFRVHGPEIAQLAGTFGLKSAGFLGLALGLINGTAGVIGAWLGGV
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
LADRLGAKDLRAYVTVPAIASVVTIPIFVVAMSLDAPMAAIGLLSVNALLATLWYGPVYA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAQSIVDPALRATASAVLLLIINLIGLGFGPLIVGLLSDILAGPVGLGEAQGVRWALIIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHH
ATLGLGAFALFWAARKTIRDEMVS
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]