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The map label for this gene is yjjL [H]

Identifier: 16126725

GI number: 16126725

Start: 2696807

End: 2698366

Strand: Direct

Name: yjjL [H]

Synonym: CC_2486

Alternate gene names: 16126725

Gene position: 2696807-2698366 (Clockwise)

Preceding gene: 16126724

Following gene: 16126726

Centisome position: 67.14

GC content: 65.83

Gene sequence:

>1560_bases
TTGGCTTCCGCTCGGTCACAGTCCCGTCAAAGATTAGAACAAATGTTTGAACGGGAGAGACACAGGATGGCCGAGGCCCA
CGCGTCCGGCGGTGATCGGCCGCTCTACTCCAACGGCTACAAGGCAACGGTGCTGGGCCTTCTGCTCGCCACCTACACCT
TCAACTTCATCGACCGGACCATCATCTCGACCATCGGTCAGGCCATCAAGGTCGACCTCAAGCTCACCGATACGCAGTTG
GGCTTGCTGGGCGGACTCTATTTCGCCCTGCTCTATACGATCCTGGGCATTCCGATCGCCCGTCTGGCCGAGCGCTTCAA
CCGGGTGACGATCATCTCGGTGTCGCTGGTGATCTGGTCAGGCTTCACCGCCCTGTGCGGCGCGGCCGCCAACTTCGCCC
AGCTGGCTCTGTTCCGCTTTGGCGTCGGGGTCGGCGAGGCCGGCTGCTCTCCGCCCAGCCACTCGCTGATCAGCGACTAT
TACGAACCCAAGAAACGGGCCACGGCCCTGTCGATCTATTCGTTCGGCATCCCACTGGGCACGATGTTCGGCGCGGTCGC
CGGCGGCTGGCTGGCCCAGGAGTTCAGCTGGCGCGTCGCCTTCGTCATCGTCGGCCTGCCCGGCATCCTGCTGGCGGTGA
TCGTCAAGCTGGTGGTCAAGGAGCCGCCGCGCGGCCATTCCGAGATCGTCGAACGCCCGCTCGAAGCCGAGGACGTCGTG
GTCGAGCCCGCCAAGCCGGCGTTCTCGATGGCCAATGAGTTCAAGGAGCTGTGGGCGGTCACCAAGATCCTGTTCGGCAA
GTGGCCGGTTCTGCACATGGTGCTGGGCGTGACCATCGCCTCGTTCGGCGCCTACGGCTCGGGGGCCTTCGTGCCGTCGT
ACTTCGTCCGCGCCTTTGACCTTGGCCTGGCGCAGGTGGGCCTGATCACCGGCCTGATCGGCGGCTTCTCGGCGGGCGTC
GGCACCCTGGTCGGCGGCTTCCTGAGCGACTGGGCCGGCAAGCGCAGCGCCAAGTGGTACGCCCTGACCCCCGCCATCGG
CCTGATCCTCTGCACGCCGATCTACATTCTGGCCTATCTGCAGACTGACTGGCAGACCACCGCCCTGATCCTGCTCGTCC
CCGGCATCTTCCATTACGTCTATCTCGCTCCGACCTTCGGCGTGGTGCAGAACTCGGTCGAGCCGCGCCGCCGGGCCACG
GCGACGGCCCTGCTGTTCTTCTTCCTGAACATCATCGCCCTGGGCGTGGGCCCGGTCTTCACCGGCTGGCTGATCGACCA
CCTGGCGCAGTTCCACTTCAACAACCCCGGCGGCGGCGTGATCGCCAGCGTGCTGGGCTCGTTCGGCGGCGAGGCGGGCC
AAAGCTTCGCCAGCGCCTGCCCGGGCGGTATCGCGCCCAAGGGCGCTTCGGCCGAACTGGTCGCCCAGTGCAAGACCACC
CTGTCGGTGGCCAGCCAGCAGGGCATCATCGTCTCTCTGTGCTTCTACGCCTGGGCAGGCCTGCACTACGCCCTGGCCGC
CATCGGCATGGTCAAGCACTTCGAGGCGCGCAAGGCTTGA

Upstream 100 bases:

>100_bases
GAGGGGGAAGCGGCAGGTTCAACAGAACTTCCCCCTCCGGCCTTCGGCCACCTCCCCCATCGGGGGAGGATTTCACCGCC
CACAAATCCCCTCTGGCGCT

Downstream 100 bases:

>100_bases
GGTTGAAAATCCTCCCCCCGGCGGGGGAGGTGTCGGCTCAAAGAGACGACGGAGGGGGAAGAGGCGAGGTCGGCAGAACT
TCCCACTCCGTCCGCTGCGC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MASARSQSRQRLEQMFERERHRMAEAHASGGDRPLYSNGYKATVLGLLLATYTFNFIDRTIISTIGQAIKVDLKLTDTQL
GLLGGLYFALLYTILGIPIARLAERFNRVTIISVSLVIWSGFTALCGAAANFAQLALFRFGVGVGEAGCSPPSHSLISDY
YEPKKRATALSIYSFGIPLGTMFGAVAGGWLAQEFSWRVAFVIVGLPGILLAVIVKLVVKEPPRGHSEIVERPLEAEDVV
VEPAKPAFSMANEFKELWAVTKILFGKWPVLHMVLGVTIASFGAYGSGAFVPSYFVRAFDLGLAQVGLITGLIGGFSAGV
GTLVGGFLSDWAGKRSAKWYALTPAIGLILCTPIYILAYLQTDWQTTALILLVPGIFHYVYLAPTFGVVQNSVEPRRRAT
ATALLFFFLNIIALGVGPVFTGWLIDHLAQFHFNNPGGGVIASVLGSFGGEAGQSFASACPGGIAPKGASAELVAQCKTT
LSVASQQGIIVSLCFYAWAGLHYALAAIGMVKHFEARKA

Sequences:

>Translated_519_residues
MASARSQSRQRLEQMFERERHRMAEAHASGGDRPLYSNGYKATVLGLLLATYTFNFIDRTIISTIGQAIKVDLKLTDTQL
GLLGGLYFALLYTILGIPIARLAERFNRVTIISVSLVIWSGFTALCGAAANFAQLALFRFGVGVGEAGCSPPSHSLISDY
YEPKKRATALSIYSFGIPLGTMFGAVAGGWLAQEFSWRVAFVIVGLPGILLAVIVKLVVKEPPRGHSEIVERPLEAEDVV
VEPAKPAFSMANEFKELWAVTKILFGKWPVLHMVLGVTIASFGAYGSGAFVPSYFVRAFDLGLAQVGLITGLIGGFSAGV
GTLVGGFLSDWAGKRSAKWYALTPAIGLILCTPIYILAYLQTDWQTTALILLVPGIFHYVYLAPTFGVVQNSVEPRRRAT
ATALLFFFLNIIALGVGPVFTGWLIDHLAQFHFNNPGGGVIASVLGSFGGEAGQSFASACPGGIAPKGASAELVAQCKTT
LSVASQQGIIVSLCFYAWAGLHYALAAIGMVKHFEARKA
>Mature_518_residues
ASARSQSRQRLEQMFERERHRMAEAHASGGDRPLYSNGYKATVLGLLLATYTFNFIDRTIISTIGQAIKVDLKLTDTQLG
LLGGLYFALLYTILGIPIARLAERFNRVTIISVSLVIWSGFTALCGAAANFAQLALFRFGVGVGEAGCSPPSHSLISDYY
EPKKRATALSIYSFGIPLGTMFGAVAGGWLAQEFSWRVAFVIVGLPGILLAVIVKLVVKEPPRGHSEIVERPLEAEDVVV
EPAKPAFSMANEFKELWAVTKILFGKWPVLHMVLGVTIASFGAYGSGAFVPSYFVRAFDLGLAQVGLITGLIGGFSAGVG
TLVGGFLSDWAGKRSAKWYALTPAIGLILCTPIYILAYLQTDWQTTALILLVPGIFHYVYLAPTFGVVQNSVEPRRRATA
TALLFFFLNIIALGVGPVFTGWLIDHLAQFHFNNPGGGVIASVLGSFGGEAGQSFASACPGGIAPKGASAELVAQCKTTL
SVASQQGIIVSLCFYAWAGLHYALAAIGMVKHFEARKA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=400, Percent_Identity=23.75, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI215490096, Length=413, Percent_Identity=23.9709443099274, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI14042968, Length=413, Percent_Identity=23.9709443099274, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI215490102, Length=195, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI2367379, Length=401, Percent_Identity=25.9351620947631, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789152, Length=344, Percent_Identity=27.0348837209302, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789515, Length=399, Percent_Identity=25.062656641604, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082404, Length=288, Percent_Identity=25.6944444444444, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=442, Percent_Identity=23.0769230769231, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193209775, Length=418, Percent_Identity=23.444976076555, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539092, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71992409, Length=413, Percent_Identity=22.0338983050847, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654039, Length=471, Percent_Identity=24.6284501061571, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17864456, Length=471, Percent_Identity=24.6284501061571, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654041, Length=469, Percent_Identity=24.0938166311301, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654037, Length=469, Percent_Identity=24.0938166311301, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654044, Length=175, Percent_Identity=31.4285714285714, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640209, Length=190, Percent_Identity=25.7894736842105, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 55558; Mature: 55427

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASARSQSRQRLEQMFERERHRMAEAHASGGDRPLYSNGYKATVLGLLLATYTFNFIDRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IISTIGQAIKVDLKLTDTQLGLLGGLYFALLYTILGIPIARLAERFNRVTIISVSLVIWS
HHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEHHHHHHC
GFTALCGAAANFAQLALFRFGVGVGEAGCSPPSHSLISDYYEPKKRATALSIYSFGIPLG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
TMFGAVAGGWLAQEFSWRVAFVIVGLPGILLAVIVKLVVKEPPRGHSEIVERPLEAEDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEE
VEPAKPAFSMANEFKELWAVTKILFGKWPVLHMVLGVTIASFGAYGSGAFVPSYFVRAFD
ECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LGLAQVGLITGLIGGFSAGVGTLVGGFLSDWAGKRSAKWYALTPAIGLILCTPIYILAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
QTDWQTTALILLVPGIFHYVYLAPTFGVVQNSVEPRRRATATALLFFFLNIIALGVGPVF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWLIDHLAQFHFNNPGGGVIASVLGSFGGEAGQSFASACPGGIAPKGASAELVAQCKTT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LSVASQQGIIVSLCFYAWAGLHYALAAIGMVKHFEARKA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASARSQSRQRLEQMFERERHRMAEAHASGGDRPLYSNGYKATVLGLLLATYTFNFIDRT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IISTIGQAIKVDLKLTDTQLGLLGGLYFALLYTILGIPIARLAERFNRVTIISVSLVIWS
HHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEHHHHHHC
GFTALCGAAANFAQLALFRFGVGVGEAGCSPPSHSLISDYYEPKKRATALSIYSFGIPLG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
TMFGAVAGGWLAQEFSWRVAFVIVGLPGILLAVIVKLVVKEPPRGHSEIVERPLEAEDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEE
VEPAKPAFSMANEFKELWAVTKILFGKWPVLHMVLGVTIASFGAYGSGAFVPSYFVRAFD
ECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LGLAQVGLITGLIGGFSAGVGTLVGGFLSDWAGKRSAKWYALTPAIGLILCTPIYILAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
QTDWQTTALILLVPGIFHYVYLAPTFGVVQNSVEPRRRATATALLFFFLNIIALGVGPVF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWLIDHLAQFHFNNPGGGVIASVLGSFGGEAGQSFASACPGGIAPKGASAELVAQCKTT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LSVASQQGIIVSLCFYAWAGLHYALAAIGMVKHFEARKA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]