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The map label for this gene is virB10 [H]

Identifier: 16126661

GI number: 16126661

Start: 2627616

End: 2628767

Strand: Direct

Name: virB10 [H]

Synonym: CC_2422

Alternate gene names: 16126661

Gene position: 2627616-2628767 (Clockwise)

Preceding gene: 16126660

Following gene: 16126662

Centisome position: 65.41

GC content: 67.8

Gene sequence:

>1152_bases
ATGACCGCGCCTTCGCCTCCCTCAGACCCCCAACTCGACAGCCCCGTGCTGCGTCCACTGGGCTACGGGCCCACCGCCGT
CAGCCGCCCACAGTCGCCGTGGGGCCTGGCGCTGGGGATCGTCGCGATCATCATCTTGGGCATGGTGGTCTACGCGTCGC
TCAGTCAGGCCCGCGAAGCGGCTCAACGTCCGCCGACGCCGCCCCCGGCGCTCGCGGCTGGGACAGCGTCGCCATCGCCC
ACAGCGTCAATGCCCGCGATCGCTGTGGCGGATAGCGGAGCGATGCAACAAGGCCTGCCCTCGCCTGAGGGCCTGCCTGA
AGGCCCTTTAACCCCGCAGACGGATACGGCTGCGCAAGAGGCGACGACGCGCTTGCGCGCCCCGGCCATGGTGGTCGATC
TGGACAGTCGCCCCGCGCCAGACGGAGACGTCCGCGTCGCGGCGACAATAGGCGCTGAGCCTGCGCCAACCCGCGCCGCC
CCGCGTCCACTCGCAGACGACAGCAAGATCTCAGCTGAAGAGCGCTTTGCTGAGAAGGTGGCCGGCTCCAACGCCGATGC
GGCGCGCGCCACGCGCTTGACTGATCCAAGCCTCGTCGCGCCGCAAGGCACGGTGATCCCGGCGATTCTGGAAACGGCGA
TCAACTCCGACCTCCCGGGCTTTGTGCGCGCTGTGGTCAGTCGCGACGTGCGCGGCTTCGATGGCTCCACCGTGCTCATA
CCGCGTGGCTCCAAGCTGATCGGCCAGTACAAGAGCGGCGTGGCCGCCGGTCAGACGCGGGCGTTCATTGTCTGGTCGCG
GGTGCTGACACCCCAGGGCGTGTCGATCGACATCGCCTCGCCGGGCGCCGACCGTCTGGGTCGCGGCGGCCTTGATGGCG
AGACCAACACTCACTTCTTCCGCAGGTTTGGGGCTTCGATCCTGCTGTCGGTGCTCAACGCAGGCCTCAACGCCGCGTCC
AACAACGGCAACGGCGGCGACAACACCGCCATCATCATCGGCTCGCCGCAGCAGGCCTCGAACATCGCCTCCATCGCCCT
GCAGCGCGAGATCGATATCCCCACGACTATCACCGTCGCCCAAGGAGCGCCGATCCGCGTGTTCGTGGCGCGCGATCTTG
ATTTTTCCGGCGTGGTTCAAAAGACGCGATGA

Upstream 100 bases:

>100_bases
CGGGGCCAACAGGTGACCCGCATCATCAATGACGGATATCGCGAGGCGACGACGGCCACCAGCCTCTCGGCTCGAAAGTC
GCGTTGAGGACTCCCAGACC

Downstream 100 bases:

>100_bases
GCACGGGGGTCTATCTCGCCGCCTACCTGGCGCCGCTGCAGCCTTGGCTGGACCGCGCTGACGTCACGGACATTTGGGTC
AACCGGCCCGGCGAGGTATG

Product: type IV secretion system protein B10

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTAPSPPSDPQLDSPVLRPLGYGPTAVSRPQSPWGLALGIVAIIILGMVVYASLSQAREAAQRPPTPPPALAAGTASPSP
TASMPAIAVADSGAMQQGLPSPEGLPEGPLTPQTDTAAQEATTRLRAPAMVVDLDSRPAPDGDVRVAATIGAEPAPTRAA
PRPLADDSKISAEERFAEKVAGSNADAARATRLTDPSLVAPQGTVIPAILETAINSDLPGFVRAVVSRDVRGFDGSTVLI
PRGSKLIGQYKSGVAAGQTRAFIVWSRVLTPQGVSIDIASPGADRLGRGGLDGETNTHFFRRFGASILLSVLNAGLNAAS
NNGNGGDNTAIIIGSPQQASNIASIALQREIDIPTTITVAQGAPIRVFVARDLDFSGVVQKTR

Sequences:

>Translated_383_residues
MTAPSPPSDPQLDSPVLRPLGYGPTAVSRPQSPWGLALGIVAIIILGMVVYASLSQAREAAQRPPTPPPALAAGTASPSP
TASMPAIAVADSGAMQQGLPSPEGLPEGPLTPQTDTAAQEATTRLRAPAMVVDLDSRPAPDGDVRVAATIGAEPAPTRAA
PRPLADDSKISAEERFAEKVAGSNADAARATRLTDPSLVAPQGTVIPAILETAINSDLPGFVRAVVSRDVRGFDGSTVLI
PRGSKLIGQYKSGVAAGQTRAFIVWSRVLTPQGVSIDIASPGADRLGRGGLDGETNTHFFRRFGASILLSVLNAGLNAAS
NNGNGGDNTAIIIGSPQQASNIASIALQREIDIPTTITVAQGAPIRVFVARDLDFSGVVQKTR
>Mature_382_residues
TAPSPPSDPQLDSPVLRPLGYGPTAVSRPQSPWGLALGIVAIIILGMVVYASLSQAREAAQRPPTPPPALAAGTASPSPT
ASMPAIAVADSGAMQQGLPSPEGLPEGPLTPQTDTAAQEATTRLRAPAMVVDLDSRPAPDGDVRVAATIGAEPAPTRAAP
RPLADDSKISAEERFAEKVAGSNADAARATRLTDPSLVAPQGTVIPAILETAINSDLPGFVRAVVSRDVRGFDGSTVLIP
RGSKLIGQYKSGVAAGQTRAFIVWSRVLTPQGVSIDIASPGADRLGRGGLDGETNTHFFRRFGASILLSVLNAGLNAASN
NGNGGDNTAIIIGSPQQASNIASIALQREIDIPTTITVAQGAPIRVFVARDLDFSGVVQKTR

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG2948

COG function: function code U; Type IV secretory pathway, VirB10 components

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbI/virB10 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005498 [H]

Pfam domain/function: PF03743 TrbI [H]

EC number: NA

Molecular weight: Translated: 39265; Mature: 39134

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSPPSDPQLDSPVLRPLGYGPTAVSRPQSPWGLALGIVAIIILGMVVYASLSQAREA
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQRPPTPPPALAAGTASPSPTASMPAIAVADSGAMQQGLPSPEGLPEGPLTPQTDTAAQE
HHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCCCCHHHHH
ATTRLRAPAMVVDLDSRPAPDGDVRVAATIGAEPAPTRAAPRPLADDSKISAEERFAEKV
HHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AGSNADAARATRLTDPSLVAPQGTVIPAILETAINSDLPGFVRAVVSRDVRGFDGSTVLI
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEE
PRGSKLIGQYKSGVAAGQTRAFIVWSRVLTPQGVSIDIASPGADRLGRGGLDGETNTHFF
ECCHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHCCCCCCCCCCHHHH
RRFGASILLSVLNAGLNAASNNGNGGDNTAIIIGSPQQASNIASIALQREIDIPTTITVA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEE
QGAPIRVFVARDLDFSGVVQKTR
CCCCEEEEEEECCCHHCHHCCCC
>Mature Secondary Structure 
TAPSPPSDPQLDSPVLRPLGYGPTAVSRPQSPWGLALGIVAIIILGMVVYASLSQAREA
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQRPPTPPPALAAGTASPSPTASMPAIAVADSGAMQQGLPSPEGLPEGPLTPQTDTAAQE
HHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCCCCHHHHH
ATTRLRAPAMVVDLDSRPAPDGDVRVAATIGAEPAPTRAAPRPLADDSKISAEERFAEKV
HHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AGSNADAARATRLTDPSLVAPQGTVIPAILETAINSDLPGFVRAVVSRDVRGFDGSTVLI
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEE
PRGSKLIGQYKSGVAAGQTRAFIVWSRVLTPQGVSIDIASPGADRLGRGGLDGETNTHFF
ECCHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHCCCCCCCCCCHHHH
RRFGASILLSVLNAGLNAASNNGNGGDNTAIIIGSPQQASNIASIALQREIDIPTTITVA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEE
QGAPIRVFVARDLDFSGVVQKTR
CCCCEEEEEEECCCHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA