Click here to switch to the map view.

The map label for this gene is hipA [H]

Identifier: 16126625

GI number: 16126625

Start: 2585969

End: 2586565

Strand: Direct

Name: hipA [H]

Synonym: CC_2386

Alternate gene names: 16126625

Gene position: 2585969-2586565 (Clockwise)

Preceding gene: 16126616

Following gene: 16126627

Centisome position: 64.38

GC content: 65.16

Gene sequence:

>597_bases
TTGCGACCTTTTTCTATCCCAACGTCGCATGATCACGGGCCCAACGGCTACGCCCTGATCCATGGGTTAGAGACTCCCCC
CACCGGCCAGGCTCCTCCGCCCCTGCCTGCAGAGATGCTGCGCCACCACGCCCGGCTGACCAAGGTCCTGACGCCTCGCT
ATGGCCCGACCGACGGCCCCGATATCGCCCAGGACACCTGGCTGCTGGGCGCCACGGACGGCCACGCCAAGAACTTCAGC
GTCGCCCTTGATCCTGGGGGTCGCTTCCGGCTGAAGCCGCTCTACGACATCCTGTCGGTTCAGCCCTTAGTCGACGCTGG
CCAGGTGCGCCACAACCAGTACAAGCTCTCGATGGCCGTCGGCCACAACCGCCACTACGCCGCGGGCTCGATCAGGCCTC
GCCATTTCATCCAGACCGCGCGGCGCGCCGAGATAGGACAAAGAGTGGTTGAGGCAGTCTTAGAGGCGCTCGGCCAGCGA
ACGCCTGCTGCGCTGGAAGCCGTTGAAGCGGGCTTGCCGGCGGAGTTTCCAGTGGGTCTCGTCAATTCCACCTTGGCTGG
AGTGCACGCTCGCCTTCAGATCGTGCGACGGGGATAG

Upstream 100 bases:

>100_bases
TAATAAAATGCACGCTGCCATTTTTAAGCGGTAGAGCCCGAGCCTCTCGCGCGCTGAGCGAAATTGCGACAACTCTTTAA
CCGCCACGTCGCAAATACTC

Downstream 100 bases:

>100_bases
ACAGGAGTGCGCCAACAGCTGCCGTTGGCGCGGATCCAGGAACGCGAGGCTTGTTGGAGACGCGTCGTGCAGTGCTGGGC
GCCCAAAATGTGATGGCCTG

Product: HipA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MRPFSIPTSHDHGPNGYALIHGLETPPTGQAPPPLPAEMLRHHARLTKVLTPRYGPTDGPDIAQDTWLLGATDGHAKNFS
VALDPGGRFRLKPLYDILSVQPLVDAGQVRHNQYKLSMAVGHNRHYAAGSIRPRHFIQTARRAEIGQRVVEAVLEALGQR
TPAALEAVEAGLPAEFPVGLVNSTLAGVHARLQIVRRG

Sequences:

>Translated_198_residues
MRPFSIPTSHDHGPNGYALIHGLETPPTGQAPPPLPAEMLRHHARLTKVLTPRYGPTDGPDIAQDTWLLGATDGHAKNFS
VALDPGGRFRLKPLYDILSVQPLVDAGQVRHNQYKLSMAVGHNRHYAAGSIRPRHFIQTARRAEIGQRVVEAVLEALGQR
TPAALEAVEAGLPAEFPVGLVNSTLAGVHARLQIVRRG
>Mature_198_residues
MRPFSIPTSHDHGPNGYALIHGLETPPTGQAPPPLPAEMLRHHARLTKVLTPRYGPTDGPDIAQDTWLLGATDGHAKNFS
VALDPGGRFRLKPLYDILSVQPLVDAGQVRHNQYKLSMAVGHNRHYAAGSIRPRHFIQTARRAEIGQRVVEAVLEALGQR
TPAALEAVEAGLPAEFPVGLVNSTLAGVHARLQIVRRG

Specific function: Unbalanced or excessive expression of hipA is toxic to the cell [H]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0665 [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=132, Percent_Identity=38.6363636363636, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 21459; Mature: 21459

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPFSIPTSHDHGPNGYALIHGLETPPTGQAPPPLPAEMLRHHARLTKVLTPRYGPTDGP
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DIAQDTWLLGATDGHAKNFSVALDPGGRFRLKPLYDILSVQPLVDAGQVRHNQYKLSMAV
CCCCCCEEEECCCCCCCCEEEEECCCCCEECHHHHHHHHCCCCHHHHHHCCCEEEEEEEE
GHNRHYAAGSIRPRHFIQTARRAEIGQRVVEAVLEALGQRTPAALEAVEAGLPAEFPVGL
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHH
VNSTLAGVHARLQIVRRG
HHHHHHHHHHHHHEEECC
>Mature Secondary Structure
MRPFSIPTSHDHGPNGYALIHGLETPPTGQAPPPLPAEMLRHHARLTKVLTPRYGPTDGP
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DIAQDTWLLGATDGHAKNFSVALDPGGRFRLKPLYDILSVQPLVDAGQVRHNQYKLSMAV
CCCCCCEEEECCCCCCCCEEEEECCCCCEECHHHHHHHHCCCCHHHHHHCCCEEEEEEEE
GHNRHYAAGSIRPRHFIQTARRAEIGQRVVEAVLEALGQRTPAALEAVEAGLPAEFPVGL
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHH
VNSTLAGVHARLQIVRRG
HHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9278503; 8021189 [H]