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The map label for this gene is czcC [H]

Identifier: 16126627

GI number: 16126627

Start: 2587684

End: 2588949

Strand: Direct

Name: czcC [H]

Synonym: CC_2388

Alternate gene names: 16126627

Gene position: 2587684-2588949 (Clockwise)

Preceding gene: 16126625

Following gene: 16126628

Centisome position: 64.42

GC content: 70.93

Gene sequence:

>1266_bases
ATGTCCAGTTTCTTCCAAGGTCGGTCGCGCCGGCCCTGGTTGTTCGCCACGGCGCTTGCCTTGGCGACGCCCCTTTCCGC
ATTCGCGGCCCCCCTGGGCCTTTCGGACGCGCTCAGCCGCGCGGCCAAGGCCGACCCTGCCCGTCCAGCGCTGGCTTCAC
GGATCGCGGCTGCAGAGGCCGGCGTCCGCCAGGCGGCTGTCCGCCCCAACCCCGTCATCGGCGTCGAGGTCGAGGACCTG
GCCGGGACGGGGCGCTACGCCCTGATCGATCGCGCTCAGGCCACGCTCTACTACCAGCAAAGCCAGGAACGGGGCGGCAA
ACGCGAGGCGCGCACGTCTCTGGCGCGCAGCGACATCGCCCAGGTTCGCCTGCGCGATGACGTCCGGATGCTCGACCTTC
TTCACGAGGTCGAGATCGCCTGGATCGAGGCGATCGCCGCCGAAGCGGAGGCGCGATTGGCCGCCGATCGTCTGGCGCTG
GCCGAACGCGCGCGCTCTGAAGTCGACCGACGCGTGAAGGTGGCGCGTGATCCCCTCTTCGCGGGGGCGCGGGCCGAGGC
CCAGGTCGCGGAAGCCGCCGGCGCCCTGGCGGAAGCCAAGGCCCGAGCCGCCAACACGCGCCGTGCTCTCGCCGCGTTCT
GGAGTGGCGGCGAGATCGAGATCGACCCTGCCCCTCTGGAAGACCTCAGCGCGGCCGATCAGATCGCCGGCCCAGCCTCG
CCCGTCGATCTGGCGCTGCTGGAGGCCCAGCGGGGCCTGGCCGCCGCCAAGGTCCGGGTCGAGCAGAGCAAGTCCGTCCA
GGACCCGACGTGGCGGGCGGGTTTGCGATATCTGAACGACGGCGGCGACGTCGCCGCGATCGTCGGTGGCTCGATCCCGC
TCGGGCGCTACGACACCAATCGCGGCGCCATCGATCAGGCCCGCGCCGCCCAGACCGCGGCCGATCTCGACCTTATCGGC
GCCAAGGCGACTCTGGAGCGGAAGATCGCCGCCGCCCAGGCTTCCCTGGCCCAGAAGGCCGGCGAGGCGCGCCGTATCAC
GGCCGAGATTATCCCCGCCAACGCCCGCACGGTCGATCTGGTCCGCGACGGGTTCAATCGCGGCGGATTTTCCTATCTCG
ACGTCATCGAGGCCCAGAGGGCGCTGATCGACGCGCGCCAACGCCGCCTCGCCGTTCTCAAATCCTTTCAGCTCGACCGC
GCCCAGCTGGACCGCCTGACCGGCGCGCACGCGAGCCTGATCCCTGCTCCGGAGTCCGCTCAATGA

Upstream 100 bases:

>100_bases
CGCCCCGCAACTCCGGGACCGTCCCCCCAAAGCCCACCTCGCCCACGTCGCTTAATCCGCGCGGCTTCAAGCGCCGCGCT
CGCACGTTCGAGGATTCTTC

Downstream 100 bases:

>100_bases
CCCGTCTTTCGCGGCGTCTGGCCGCCGTCCCTCTCGCCCTTGCCATTGCCGGGACCCTTGCGCTCTCCGCTTGCGGTGAA
CGCCCCAAACCCGCCGAAAC

Product: metal ion efflux outer membrane factor protein family

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSSFFQGRSRRPWLFATALALATPLSAFAAPLGLSDALSRAAKADPARPALASRIAAAEAGVRQAAVRPNPVIGVEVEDL
AGTGRYALIDRAQATLYYQQSQERGGKREARTSLARSDIAQVRLRDDVRMLDLLHEVEIAWIEAIAAEAEARLAADRLAL
AERARSEVDRRVKVARDPLFAGARAEAQVAEAAGALAEAKARAANTRRALAAFWSGGEIEIDPAPLEDLSAADQIAGPAS
PVDLALLEAQRGLAAAKVRVEQSKSVQDPTWRAGLRYLNDGGDVAAIVGGSIPLGRYDTNRGAIDQARAAQTAADLDLIG
AKATLERKIAAAQASLAQKAGEARRITAEIIPANARTVDLVRDGFNRGGFSYLDVIEAQRALIDARQRRLAVLKSFQLDR
AQLDRLTGAHASLIPAPESAQ

Sequences:

>Translated_421_residues
MSSFFQGRSRRPWLFATALALATPLSAFAAPLGLSDALSRAAKADPARPALASRIAAAEAGVRQAAVRPNPVIGVEVEDL
AGTGRYALIDRAQATLYYQQSQERGGKREARTSLARSDIAQVRLRDDVRMLDLLHEVEIAWIEAIAAEAEARLAADRLAL
AERARSEVDRRVKVARDPLFAGARAEAQVAEAAGALAEAKARAANTRRALAAFWSGGEIEIDPAPLEDLSAADQIAGPAS
PVDLALLEAQRGLAAAKVRVEQSKSVQDPTWRAGLRYLNDGGDVAAIVGGSIPLGRYDTNRGAIDQARAAQTAADLDLIG
AKATLERKIAAAQASLAQKAGEARRITAEIIPANARTVDLVRDGFNRGGFSYLDVIEAQRALIDARQRRLAVLKSFQLDR
AQLDRLTGAHASLIPAPESAQ
>Mature_420_residues
SSFFQGRSRRPWLFATALALATPLSAFAAPLGLSDALSRAAKADPARPALASRIAAAEAGVRQAAVRPNPVIGVEVEDLA
GTGRYALIDRAQATLYYQQSQERGGKREARTSLARSDIAQVRLRDDVRMLDLLHEVEIAWIEAIAAEAEARLAADRLALA
ERARSEVDRRVKVARDPLFAGARAEAQVAEAAGALAEAKARAANTRRALAAFWSGGEIEIDPAPLEDLSAADQIAGPASP
VDLALLEAQRGLAAAKVRVEQSKSVQDPTWRAGLRYLNDGGDVAAIVGGSIPLGRYDTNRGAIDQARAAQTAADLDLIGA
KATLERKIAAAQASLAQKAGEARRITAEIIPANARTVDLVRDGFNRGGFSYLDVIEAQRALIDARQRRLAVLKSFQLDRA
QLDRLTGAHASLIPAPESAQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 44762; Mature: 44631

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFFQGRSRRPWLFATALALATPLSAFAAPLGLSDALSRAAKADPARPALASRIAAAEA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GVRQAAVRPNPVIGVEVEDLAGTGRYALIDRAQATLYYQQSQERGGKREARTSLARSDIA
HHHHHCCCCCCEEEEEEHHHCCCCCEEEEEHHHHHHEEHHHHHCCCHHHHHHHHHHHHHH
QVRLRDDVRMLDLLHEVEIAWIEAIAAEAEARLAADRLALAERARSEVDRRVKVARDPLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGARAEAQVAEAAGALAEAKARAANTRRALAAFWSGGEIEIDPAPLEDLSAADQIAGPAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCC
PVDLALLEAQRGLAAAKVRVEQSKSVQDPTWRAGLRYLNDGGDVAAIVGGSIPLGRYDTN
CHHHHHHHHHCCHHHHHEEHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
RGAIDQARAAQTAADLDLIGAKATLERKIAAAQASLAQKAGEARRITAEIIPANARTVDL
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCHHH
VRDGFNRGGFSYLDVIEAQRALIDARQRRLAVLKSFQLDRAQLDRLTGAHASLIPAPESA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEECCCCCCC
Q
C
>Mature Secondary Structure 
SSFFQGRSRRPWLFATALALATPLSAFAAPLGLSDALSRAAKADPARPALASRIAAAEA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GVRQAAVRPNPVIGVEVEDLAGTGRYALIDRAQATLYYQQSQERGGKREARTSLARSDIA
HHHHHCCCCCCEEEEEEHHHCCCCCEEEEEHHHHHHEEHHHHHCCCHHHHHHHHHHHHHH
QVRLRDDVRMLDLLHEVEIAWIEAIAAEAEARLAADRLALAERARSEVDRRVKVARDPLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGARAEAQVAEAAGALAEAKARAANTRRALAAFWSGGEIEIDPAPLEDLSAADQIAGPAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCC
PVDLALLEAQRGLAAAKVRVEQSKSVQDPTWRAGLRYLNDGGDVAAIVGGSIPLGRYDTN
CHHHHHHHHHCCHHHHHEEHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
RGAIDQARAAQTAADLDLIGAKATLERKIAAAQASLAQKAGEARRITAEIIPANARTVDL
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCHHH
VRDGFNRGGFSYLDVIEAQRALIDARQRRLAVLKSFQLDRAQLDRLTGAHASLIPAPESA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEECCCCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]