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The map label for this gene is hup1 [H]

Identifier: 16126570

GI number: 16126570

Start: 2534155

End: 2534433

Strand: Direct

Name: hup1 [H]

Synonym: CC_2331

Alternate gene names: 16126570

Gene position: 2534155-2534433 (Clockwise)

Preceding gene: 16126569

Following gene: 16126571

Centisome position: 63.09

GC content: 64.16

Gene sequence:

>279_bases
ATGAACGTTTCCGATCTGGTCGACGCCGCTGTCGCCGCCGACGAAAAACTGACGAAGACCCAGGCCAAGGCCATCATCGA
CGGCGTCTTCAAGTCGATCTCCGACGCCGCCGTGAAGGGCGAGGAAGTCTCGATCCCCGGCTTCGGCAAGTTCAAGGTCC
AGGCTAAGCCGGCCCGCACCGGCCGCAACCCGGCCACCGGCGCGACCATCGAAATCGCCGCCAGCAAGAAGGTCGGCTTC
ACGCCGGCCAAGCAACTGAAGGACGCCGTCAACGGCTAA

Upstream 100 bases:

>100_bases
TCCCCGTGAATCGGCATTTTAACCTTTCCTAACGGGTGACAAACGCGATCGGCGTCGTCAGGCTCGAACTTCCCTGATTC
ACAGGAATGAGCTTTAGAAG

Downstream 100 bases:

>100_bases
GCCTTCAGAGAGGGGCCGGCCCTTCGGGCGCAGGTCTCTCACTGCGACTTCGGGGTGCGACATCCAGCCTAGTGCGGATG
TTGCACCCTAAGTCTTTTCA

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 92; Mature: 92

Protein sequence:

>92_residues
MNVSDLVDAAVAADEKLTKTQAKAIIDGVFKSISDAAVKGEEVSIPGFGKFKVQAKPARTGRNPATGATIEIAASKKVGF
TPAKQLKDAVNG

Sequences:

>Translated_92_residues
MNVSDLVDAAVAADEKLTKTQAKAIIDGVFKSISDAAVKGEEVSIPGFGKFKVQAKPARTGRNPATGATIEIAASKKVGF
TPAKQLKDAVNG
>Mature_92_residues
MNVSDLVDAAVAADEKLTKTQAKAIIDGVFKSISDAAVKGEEVSIPGFGKFKVQAKPARTGRNPATGATIEIAASKKVGF
TPAKQLKDAVNG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=44.4444444444444, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1786644, Length=91, Percent_Identity=43.956043956044, Blast_Score=72, Evalue=5e-15,
Organism=Escherichia coli, GI1788005, Length=74, Percent_Identity=41.8918918918919, Blast_Score=63, Evalue=3e-12,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9457; Mature: 9457

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSDLVDAAVAADEKLTKTQAKAIIDGVFKSISDAAVKGEEVSIPGFGKFKVQAKPART
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEECCCCC
GRNPATGATIEIAASKKVGFTPAKQLKDAVNG
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNVSDLVDAAVAADEKLTKTQAKAIIDGVFKSISDAAVKGEEVSIPGFGKFKVQAKPART
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEECCCCC
GRNPATGATIEIAASKKVGFTPAKQLKDAVNG
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]