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The map label for this gene is ilvH

Identifier: 16126340

GI number: 16126340

Start: 2311898

End: 2312455

Strand: Direct

Name: ilvH

Synonym: CC_2101

Alternate gene names: 16126340

Gene position: 2311898-2312455 (Clockwise)

Preceding gene: 16126339

Following gene: 16126341

Centisome position: 57.55

GC content: 66.85

Gene sequence:

>558_bases
ATGACCGCCAACGTGCAACCCGCTCCCGCCTCGGCCTACGACCTTAGCCCCAAGGACCAGGCCGAACAGTCCGCCACCTT
CGCCCTCCTCGTCGACAACGAGCCCGGCGTCCTGCATCGCGTGGTCGGCCTGTTCGCCGCGCGGGGCTACAATATCGAGA
GCCTCACCGTCGCCGAGACGGACCGCAAGGCGCACACCAGCCGTATCACCGTGGTGACCCGCGGCACCCGCCATGTGCTG
GACCAGATCGAGGCCCAGCTAAACAAGGTGGTCAATGTCCGCCGCGTCCACGACGTGACCCGCGATCCGAACGGCGTCGA
GCGCGAGCTGGCCCTGGTGAAGGTGCGCGGCTCTGGCGTCGATCGCCTGGAAGCGCTGCGGATCGCCGAGATCTTCCGCG
CCAAGCCGGTCGACACCACCCTTGAGAGCTTCGTCTTCGAGATCTCCGGTGCGCCGTCCAAGATCGACAAGTTCCTCGAC
CTGATGCGCCCCCTGGGCCTGGTGGAGCTGTCCCGTACGGGCGTTCTCTCCATCGAGCGCGGCTTCGAAGGCATGTAG

Upstream 100 bases:

>100_bases
GGGCGAGGTCGAGGACATCGGCAACGTCATCGGCGAGGACGGCGCGGGGCTGGTCTAAGCCCCCTCGCCCTTCCACAACC
CTTTGGCTTAGAAGCGATCC

Downstream 100 bases:

>100_bases
CCGAGGGTGGTTGGGGACAACGCGCCCCCTCACCCTTCCATTGGCTGGGCGAAGTCCCTATATTGGATCTGTCCGGCTTC
GGCCGAACTATGGGGATAAA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTANVQPAPASAYDLSPKDQAEQSATFALLVDNEPGVLHRVVGLFAARGYNIESLTVAETDRKAHTSRITVVTRGTRHVL
DQIEAQLNKVVNVRRVHDVTRDPNGVERELALVKVRGSGVDRLEALRIAEIFRAKPVDTTLESFVFEISGAPSKIDKFLD
LMRPLGLVELSRTGVLSIERGFEGM

Sequences:

>Translated_185_residues
MTANVQPAPASAYDLSPKDQAEQSATFALLVDNEPGVLHRVVGLFAARGYNIESLTVAETDRKAHTSRITVVTRGTRHVL
DQIEAQLNKVVNVRRVHDVTRDPNGVERELALVKVRGSGVDRLEALRIAEIFRAKPVDTTLESFVFEISGAPSKIDKFLD
LMRPLGLVELSRTGVLSIERGFEGM
>Mature_184_residues
TANVQPAPASAYDLSPKDQAEQSATFALLVDNEPGVLHRVVGLFAARGYNIESLTVAETDRKAHTSRITVVTRGTRHVLD
QIEAQLNKVVNVRRVHDVTRDPNGVERELALVKVRGSGVDRLEALRIAEIFRAKPVDTTLESFVFEISGAPSKIDKFLDL
MRPLGLVELSRTGVLSIERGFEGM

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=156, Percent_Identity=45.5128205128205, Blast_Score=126, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6319837, Length=214, Percent_Identity=29.4392523364486, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 20346; Mature: 20214

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANVQPAPASAYDLSPKDQAEQSATFALLVDNEPGVLHRVVGLFAARGYNIESLTVAET
CCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECC
DRKAHTSRITVVTRGTRHVLDQIEAQLNKVVNVRRVHDVTRDPNGVERELALVKVRGSGV
CCHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCC
DRLEALRIAEIFRAKPVDTTLESFVFEISGAPSKIDKFLDLMRPLGLVELSRTGVLSIER
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCEEEECC
GFEGM
CCCCC
>Mature Secondary Structure 
TANVQPAPASAYDLSPKDQAEQSATFALLVDNEPGVLHRVVGLFAARGYNIESLTVAET
CCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECC
DRKAHTSRITVVTRGTRHVLDQIEAQLNKVVNVRRVHDVTRDPNGVERELALVKVRGSGV
CCHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCC
DRLEALRIAEIFRAKPVDTTLESFVFEISGAPSKIDKFLDLMRPLGLVELSRTGVLSIER
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCEEEECC
GFEGM
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]