BacMap

Definition	Caulobacter crescentus CB15 chromosome, complete genome.
Accession	NC_002696
Length	4,016,947

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The map label for this gene is butA [H]

Identifier: 16126047

GI number: 16126047

Start: 1993804

End: 1994547

Strand: Direct

Name: butA [H]

Synonym: CC_1803

Alternate gene names: 16126047

Gene position: 1993804-1994547 (Clockwise)

Preceding gene: 16126046

Following gene: 16126048

Centisome position: 49.63

GC content: 69.76

Gene sequence:

>744_bases
ATGAGGAGGAATTCAGTCATGCCGCAACTGGCCATGGTCACCGGGGCCGCACAGGGCATCGGGCGCGCCATCGTCGAGCG
CCTTGGCGCGGACGGCTTTGACATCCTGGCGCTGGACGCGGACGAAACCCAGCTTTCGCGGTCCGCCGCAGACTGGCGCG
AAGCCGGACTGACGGTTCGCACCGCCGCCGCCGACTGCCGTGATCGCGCCGCGGTGATCAAGGCTCTGGACGGGGTCGAG
GCGGTGAACGTCCTCGTGAACAACGCCGGGATCAGCGGTGTTCTGGACCCGATCGGCCAGGTCAATCGGGCGGCTTGCGA
CCGCGTGATGGGCGTCAATCTGCTGGCGACGATCCGGGTCGCGCAGGAGGCTGTCCGTCGCATGCCCGACGGCGGCAGCG
TCATCAACATCGCCTCGCGCGGCTATCTCGGCGGGGCCGGGGCCGCCCACTATGTGGCCTCCAAGGCTGCGGTCGTCTCG
CTGACCCGGGCCATGGCGATCGAGCTGCGCTGGCGCGGCGTCCGCGTCAACGCGGTGGCCCCCGGCATGGTCGACACCCG
GATGATCGACGGCTTTGGCGACATGCTGGGCGCGCTCAAGCGCATGGAGCCGACCGGAGCGCCCGCCAACCCGGCCGAGA
TCGCCGCCATTGTCAGCGTCCTGGCCGGACCGGAGGCCAGCTTCGTCAACGGCCAGATCCTGATGGCCGACGGCGGGAAA
TCCCTGGGACTGCCGCCGCTATGA

Upstream 100 bases:

>100_bases
GCGGCGCTCGAAACCCTCGTCTGATCCATCACCCATGTGATTAGCGCCGCCGCCGGCGATCGGATGTCCGCGCCGTCGGC
GAGCTGGCGTTTGCTGCGCC

Downstream 100 bases:

>100_bases
ACACGTCCAACCCATCGTTCCTGATCATCGGCCAGGGACCGGTCGCCGAGGCGATTCTGAGCCGCGTGAGCGTCGAGGGC
GGCGGCGTCATCACCCTGGC

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRRNSVMPQLAMVTGAAQGIGRAIVERLGADGFDILALDADETQLSRSAADWREAGLTVRTAAADCRDRAAVIKALDGVE
AVNVLVNNAGISGVLDPIGQVNRAACDRVMGVNLLATIRVAQEAVRRMPDGGSVINIASRGYLGGAGAAHYVASKAAVVS
LTRAMAIELRWRGVRVNAVAPGMVDTRMIDGFGDMLGALKRMEPTGAPANPAEIAAIVSVLAGPEASFVNGQILMADGGK
SLGLPPL

Sequences:

>Translated_247_residues
MRRNSVMPQLAMVTGAAQGIGRAIVERLGADGFDILALDADETQLSRSAADWREAGLTVRTAAADCRDRAAVIKALDGVE
AVNVLVNNAGISGVLDPIGQVNRAACDRVMGVNLLATIRVAQEAVRRMPDGGSVINIASRGYLGGAGAAHYVASKAAVVS
LTRAMAIELRWRGVRVNAVAPGMVDTRMIDGFGDMLGALKRMEPTGAPANPAEIAAIVSVLAGPEASFVNGQILMADGGK
SLGLPPL
>Mature_247_residues
MRRNSVMPQLAMVTGAAQGIGRAIVERLGADGFDILALDADETQLSRSAADWREAGLTVRTAAADCRDRAAVIKALDGVE
AVNVLVNNAGISGVLDPIGQVNRAACDRVMGVNLLATIRVAQEAVRRMPDGGSVINIASRGYLGGAGAAHYVASKAAVVS
LTRAMAIELRWRGVRVNAVAPGMVDTRMIDGFGDMLGALKRMEPTGAPANPAEIAAIVSVLAGPEASFVNGQILMADGGK
SLGLPPL

Specific function: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=31.3492063492063, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=32.2834645669291, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=30.5220883534137, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=187, Percent_Identity=35.8288770053476, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=30.6772908366534, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI142976729, Length=213, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=31.1224489795918, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=172, Percent_Identity=31.3953488372093, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI66933014, Length=227, Percent_Identity=29.0748898678414, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=31.496062992126, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367365, Length=232, Percent_Identity=34.9137931034483, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=30.672268907563, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=31.6666666666667, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=30.3501945525292, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=29.3172690763052, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=31.496062992126, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786701, Length=232, Percent_Identity=27.5862068965517, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=30.5660377358491, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=28.735632183908, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=29.277566539924, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=31.2977099236641, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=29.4573643410853, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=30.9433962264151, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=31.2757201646091, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=28.957528957529, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=27.7551020408163, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=30.5660377358491, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=31.6872427983539, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=27.9850746268657, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=29.8039215686275, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=27.1653543307087, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=31.9327731092437, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=25.6505576208178, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=27.7566539923954, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=27.1698113207547, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=25.7261410788382, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=26.2548262548263, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=28.2945736434109, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=26.953125, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.4436090225564, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193207185, Length=151, Percent_Identity=35.0993377483444, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=28.3400809716599, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=225, Percent_Identity=29.7777777777778, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=32.9166666666667, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=33.739837398374, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=26.8595041322314, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.4741035856574, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.3149606299213, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=30.46875, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.5882352941176, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=34.0909090909091, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 25466; Mature: 25466

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNSVMPQLAMVTGAAQGIGRAIVERLGADGFDILALDADETQLSRSAADWREAGLTVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
TAAADCRDRAAVIKALDGVEAVNVLVNNAGISGVLDPIGQVNRAACDRVMGVNLLATIRV
EHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQEAVRRMPDGGSVINIASRGYLGGAGAAHYVASKAAVVSLTRAMAIELRWRGVRVNAVA
HHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCEEEEEEC
PGMVDTRMIDGFGDMLGALKRMEPTGAPANPAEIAAIVSVLAGPEASFVNGQILMADGGK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEECCEEEEECCCC
SLGLPPL
CCCCCCC
>Mature Secondary Structure
MRRNSVMPQLAMVTGAAQGIGRAIVERLGADGFDILALDADETQLSRSAADWREAGLTVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
TAAADCRDRAAVIKALDGVEAVNVLVNNAGISGVLDPIGQVNRAACDRVMGVNLLATIRV
EHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQEAVRRMPDGGSVINIASRGYLGGAGAAHYVASKAAVVSLTRAMAIELRWRGVRVNAVA
HHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCEEEEEEC
PGMVDTRMIDGFGDMLGALKRMEPTGAPANPAEIAAIVSVLAGPEASFVNGQILMADGGK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEECCEEEEECCCC
SLGLPPL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA