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The map label for this gene is hfq

Identifier: 16125989

GI number: 16125989

Start: 1919986

End: 1920234

Strand: Direct

Name: hfq

Synonym: CC_1745

Alternate gene names: 16125989

Gene position: 1919986-1920234 (Clockwise)

Preceding gene: 16125988

Following gene: 16125990

Centisome position: 47.8

GC content: 58.23

Gene sequence:

>249_bases
ATGTCCGCCGAAAAGAAGCAAAATCTTCAGGACACCTTCCTGAACAGCGTTCGCAAGTCGAAGACGCCGCTCACCATCTT
CCTCGTCAATGGCGTCAAGCTGCAGGGCGTGGTCAGCTGGTTCGACAATTTCTGCGTCCTGCTGCGTCGCGACGGCCAGT
CGCAACTGGTCTACAAGCACGCCATTTCCACCATCATGCCGGCTCAACCCGTTCAGCTCTATGAGCCGAGCGCCGACGCC
GACGACTGA

Upstream 100 bases:

>100_bases
CGCTGCGAGCGTGTCGCTTTCGGCGAAAAATCCTCTAGCATGACCTTGTTTGTGTGGGGGGCGTGTGGCCCTCCGAGAAC
AATGAGAGGGGAACCCCCGT

Downstream 100 bases:

>100_bases
CCCTAGAGCCGTTTGTCCAAATCCAGTTCCAAGTCGATTGACCACGCCGCGCCGATCCTGAAGGCGCTCGTGATCCATCC
CGCACGCCCTTTGCGGGGCC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MSAEKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHAISTIMPAQPVQLYEPSADA
DD

Sequences:

>Translated_82_residues
MSAEKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHAISTIMPAQPVQLYEPSADA
DD
>Mature_81_residues
SAEKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHAISTIMPAQPVQLYEPSADAD
D

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=76, Percent_Identity=50, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_CAUCN (B8GW92)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002517192.1
- ProteinModelPortal:   B8GW92
- SMR:   B8GW92
- GeneID:   7331286
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01819
- OMA:   KNTVTQM
- ProtClustDB:   PRK00395
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9242; Mature: 9110

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKH
CCCCHHCCHHHHHHHHHHCCCCCEEEEEECCEEHHHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPAQPVQLYEPSADADD
HHHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
SAEKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKH
CCCHHCCHHHHHHHHHHCCCCCEEEEEECCEEHHHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPAQPVQLYEPSADADD
HHHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA