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The map label for this gene is hflX [H]

Identifier: 16125990

GI number: 16125990

Start: 1920304

End: 1921587

Strand: Direct

Name: hflX [H]

Synonym: CC_1746

Alternate gene names: 16125990

Gene position: 1920304-1921587 (Clockwise)

Preceding gene: 16125989

Following gene: 16125993

Centisome position: 47.81

GC content: 68.54

Gene sequence:

>1284_bases
GTGATCCATCCCGCACGCCCTTTGCGGGGCCAGGCCGCCCTCGAAGCCCGGGATCCCAACGCCCGGCTCGAGGAGGCCGT
CGGCCTTGCGGTGGCGCTTGATCTCAACGTCGTGGAGGCGCTGGTCGCGCCTCTGCGCGTCGTCACGCCCGCCACCTTAT
TCGGCAAGGGCAAGGTCGAGGAGTTCGCCGCGATCTGCGAGGTCGAGCATATCGATGTCGCGGTCTTCGACGACCAGCTC
ACGCCCATCCAGCAGCGTAATCTCGAGAAGGCTTTGAAGGTGAAGGTCGTCGACCGCACCGGCCTGATCCTCGAAATCTT
CGCCCGCCGGGCCCGGACCCGCGAGGGCCGTCTGCAGGTCGAGCTGGCCAGGCTCGACTATGAGCGCTCGCGCCTCGTGC
GGACCTGGACCCACCTGGAACGTCAGCGCGGCGGCACCGGCTCGACCGGCGGCCCCGGCGAAACCCAGATCGAAATCGAC
CGCCGCCTGATCGCCGGCACGATCCTCAAGCTCAAGAAGGAGCTCGAGGAGGTTCGGCGGACGCGCACGCTGCATCGCAG
CGCTCGCAAAAAGGTTCCGTACCCGACCGTCGCCCTGGTCGGCTACACGAACGCCGGCAAGTCCACGCTGTTCAATCGGC
TGACCGAGGCCGAGGTGCTGGCCAAGGACATGCTGTTCGCCACGCTGGACCCGACGCTTCGCACCGTGAAGCTGCCCGAC
GGTCGCCCCGCGATCATGTCCGATACGGTGGGCTTCATCTCCGACCTGCCGCACGAGTTGGTCGAGGCTTTCCGCGCCAC
CCTCGAGGAGGTGCAGGAGGCTGACGTCGTGCTGCACGTCCGCGATGTGGCCAATCCCGACAGCGAGGCGCAAGCCCGCG
ACGTCGAGACGGTGCTCGCCGAACTGGGCGTCACGCTCGACGAGGGCAAGACTGTCGTCGAGGTCTGGAACAAGGTCGAC
CTGCTGTCGGAAGATGATCGCGAGATCGTCGAGGGACAGGCCCGGCGCAACGACGCCTCGGCGGTTTCGGCGGTCACGGG
CGAGGGGTGCGAGGCGCTGCTGCGGCGCATCGCGGGCCTCATCGATGACTCGCCCCCGGTGGAGGTGAGCCTCGCCGCAC
AGGACGGACAGGCCCTGGCCTGGATCTATCGCAACGGCCGCGTGCTCAGCCGCTATGACGGCCCAGGCGGCGAGGTGACG
CTGGTCGCCCGCCTCGATGCTCAGGCCCTGGGGCGGTTCGAGCGCCAGTTCCCCGGCGCGCAGGTCTCGGCGGCGGTCGA
CTAA

Upstream 100 bases:

>100_bases
CTATGAGCCGAGCGCCGACGCCGACGACTGACCCTAGAGCCGTTTGTCCAAATCCAGTTCCAAGTCGATTGACCACGCCG
CGCCGATCCTGAAGGCGCTC

Downstream 100 bases:

>100_bases
ACCTTCTTCTCCGCGGCCTTGGCGTCGTTCCAGAGCCCGTCCATTTCGGCGAGATCGGACTGATCAGGCGTCTTGCCGCG
CTTGGCCAGTTCGGTCTCGA

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MIHPARPLRGQAALEARDPNARLEEAVGLAVALDLNVVEALVAPLRVVTPATLFGKGKVEEFAAICEVEHIDVAVFDDQL
TPIQQRNLEKALKVKVVDRTGLILEIFARRARTREGRLQVELARLDYERSRLVRTWTHLERQRGGTGSTGGPGETQIEID
RRLIAGTILKLKKELEEVRRTRTLHRSARKKVPYPTVALVGYTNAGKSTLFNRLTEAEVLAKDMLFATLDPTLRTVKLPD
GRPAIMSDTVGFISDLPHELVEAFRATLEEVQEADVVLHVRDVANPDSEAQARDVETVLAELGVTLDEGKTVVEVWNKVD
LLSEDDREIVEGQARRNDASAVSAVTGEGCEALLRRIAGLIDDSPPVEVSLAAQDGQALAWIYRNGRVLSRYDGPGGEVT
LVARLDAQALGRFERQFPGAQVSAAVD

Sequences:

>Translated_427_residues
MIHPARPLRGQAALEARDPNARLEEAVGLAVALDLNVVEALVAPLRVVTPATLFGKGKVEEFAAICEVEHIDVAVFDDQL
TPIQQRNLEKALKVKVVDRTGLILEIFARRARTREGRLQVELARLDYERSRLVRTWTHLERQRGGTGSTGGPGETQIEID
RRLIAGTILKLKKELEEVRRTRTLHRSARKKVPYPTVALVGYTNAGKSTLFNRLTEAEVLAKDMLFATLDPTLRTVKLPD
GRPAIMSDTVGFISDLPHELVEAFRATLEEVQEADVVLHVRDVANPDSEAQARDVETVLAELGVTLDEGKTVVEVWNKVD
LLSEDDREIVEGQARRNDASAVSAVTGEGCEALLRRIAGLIDDSPPVEVSLAAQDGQALAWIYRNGRVLSRYDGPGGEVT
LVARLDAQALGRFERQFPGAQVSAAVD
>Mature_427_residues
MIHPARPLRGQAALEARDPNARLEEAVGLAVALDLNVVEALVAPLRVVTPATLFGKGKVEEFAAICEVEHIDVAVFDDQL
TPIQQRNLEKALKVKVVDRTGLILEIFARRARTREGRLQVELARLDYERSRLVRTWTHLERQRGGTGSTGGPGETQIEID
RRLIAGTILKLKKELEEVRRTRTLHRSARKKVPYPTVALVGYTNAGKSTLFNRLTEAEVLAKDMLFATLDPTLRTVKLPD
GRPAIMSDTVGFISDLPHELVEAFRATLEEVQEADVVLHVRDVANPDSEAQARDVETVLAELGVTLDEGKTVVEVWNKVD
LLSEDDREIVEGQARRNDASAVSAVTGEGCEALLRRIAGLIDDSPPVEVSLAAQDGQALAWIYRNGRVLSRYDGPGGEVT
LVARLDAQALGRFERQFPGAQVSAAVD

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=277, Percent_Identity=35.0180505415162, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310124267, Length=277, Percent_Identity=35.0180505415162, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310124171, Length=277, Percent_Identity=35.0180505415162, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310124169, Length=277, Percent_Identity=35.0180505415162, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310133118, Length=319, Percent_Identity=34.7962382445141, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310133116, Length=298, Percent_Identity=34.8993288590604, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1790615, Length=402, Percent_Identity=42.7860696517413, Blast_Score=277, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17561038, Length=435, Percent_Identity=31.9540229885057, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24650079, Length=428, Percent_Identity=33.1775700934579, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 46897; Mature: 46897

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHPARPLRGQAALEARDPNARLEEAVGLAVALDLNVVEALVAPLRVVTPATLFGKGKVE
CCCCCCCCCCCCEEECCCCCHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCHHHCCCCCHH
EFAAICEVEHIDVAVFDDQLTPIQQRNLEKALKVKVVDRTGLILEIFARRARTREGRLQV
HHHHHHHHEECEEEEECCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCEEE
ELARLDYERSRLVRTWTHLERQRGGTGSTGGPGETQIEIDRRLIAGTILKLKKELEEVRR
EEEHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
TRTLHRSARKKVPYPTVALVGYTNAGKSTLFNRLTEAEVLAKDMLFATLDPTLRTVKLPD
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GRPAIMSDTVGFISDLPHELVEAFRATLEEVQEADVVLHVRDVANPDSEAQARDVETVLA
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHH
ELGVTLDEGKTVVEVWNKVDLLSEDDREIVEGQARRNDASAVSAVTGEGCEALLRRIAGL
HHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCHHCCCCHHHHHHHCCCCHHHHHHHHHHH
IDDSPPVEVSLAAQDGQALAWIYRNGRVLSRYDGPGGEVTLVARLDAQALGRFERQFPGA
CCCCCCCEEEEECCCCCEEEEEEECCEEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCC
QVSAAVD
CEEECCC
>Mature Secondary Structure
MIHPARPLRGQAALEARDPNARLEEAVGLAVALDLNVVEALVAPLRVVTPATLFGKGKVE
CCCCCCCCCCCCEEECCCCCHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCHHHCCCCCHH
EFAAICEVEHIDVAVFDDQLTPIQQRNLEKALKVKVVDRTGLILEIFARRARTREGRLQV
HHHHHHHHEECEEEEECCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCEEE
ELARLDYERSRLVRTWTHLERQRGGTGSTGGPGETQIEIDRRLIAGTILKLKKELEEVRR
EEEHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
TRTLHRSARKKVPYPTVALVGYTNAGKSTLFNRLTEAEVLAKDMLFATLDPTLRTVKLPD
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GRPAIMSDTVGFISDLPHELVEAFRATLEEVQEADVVLHVRDVANPDSEAQARDVETVLA
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHH
ELGVTLDEGKTVVEVWNKVDLLSEDDREIVEGQARRNDASAVSAVTGEGCEALLRRIAGL
HHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCHHCCCCHHHHHHHCCCCHHHHHHHHHHH
IDDSPPVEVSLAAQDGQALAWIYRNGRVLSRYDGPGGEVTLVARLDAQALGRFERQFPGA
CCCCCCCEEEEECCCCCEEEEEEECCEEEEEECCCCCCEEEEEECCHHHHHHHHHHCCCC
QVSAAVD
CEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]