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The map label for this gene is ampC [H]

Identifier: 16125950

GI number: 16125950

Start: 1879282

End: 1880520

Strand: Direct

Name: ampC [H]

Synonym: CC_1706

Alternate gene names: 16125950

Gene position: 1879282-1880520 (Clockwise)

Preceding gene: 16125949

Following gene: 16125958

Centisome position: 46.78

GC content: 67.47

Gene sequence:

>1239_bases
GTGGCCGTCGGCGCGGCGGTGCTGCTGCTGCTGCTTCTCGGCGCGATGCTCCTGCCGCGCACCACCGGTCGCCTGACGAG
CGCGCCGCATGGTCTGGCCGCCGCGCCCGCGCCGCCCGAGCGGCCGCAAGACTGGCGGGGCGACATCGATTATCGCGCCA
TGGACAGCCGCCTGCGGGCGATGATGACCGATCGGTCGATGCAGGGACTGGCGGTCGCCGTCGTCGAGAAGGGGCGACTT
TCCTTCGTTCAGGGCTATGGCGTCACAGCAGAGGGCGGGGCGCCGGTGGATGCGCGGACCGTGTTCCGCTGGGCCTCGCT
GTCGAAAACCGTCGCGGGAACCCTGACCGCCCGATTGGCGGCCGATGGCGCGCTATCACTTCAGGATCCGCTTTCGGCGT
TCGACACCAGTCTGAAGCTGCCCGGCGACGCGCAGGTGGGCTTGACGCTGGAGCAACTGCTTTCCCAGCGCACGGGCCTG
GGTCGCAACGCCTACGATGGTCGGCTGGAGGACGGGGAGGACCCGAACGTCATTCGCGGATCGTTCGCGGCGCTGAAGCC
GGTGTGTCCGCCCGGGACCTGTCACACCTATCAGAACATCGCCTATGACACGATCACCGAGGTGATCCACGCGCGCACCG
GTCTAGACTATGCCGAAGCGGTCAAACGCCGCCTGTTCGAGCCGCTGGGCATGAAGAGCACGACTTTCGGGGAGGCCGGT
TTGAAGTCCTCGGCCCAATGGGCCAGGCCGACGCGTCACGGTCGTGCGCTGCCGTTCTCTGATGCGTACTATCACGTGCC
GGCTGCAGCGGGGGTGAACTCGACGATCGTGGACCTGGCGATCTGGATGCAGGCCCAGATGGGGTTGCGGCCCGACGTGC
TGTCGCCGTCCGTACTGGGCGAGGTTCAACGGTCCCGGGTCGGCACCGGGCGTCCCTACGGCCGCCTCAATATCGCGCGG
GAGCTCAAGGGACCGGGCTATGGCCTTGGCATGCGCAGCTTCACCTACCGCGGTCACGATCTGGTCGGCCACAGCGGCGG
GGTGGCGGGGTATCGCGCGACCATGATGTTCGAGCCGGCGACGCGGACGGGCATCGTCATGCTGTGGAACAGCGACGCCA
ACCTGCCGTTCCGCTACCAGGCCGAGTTCTTTGACCGCGTCTACGGGCTGCCCTTCACCGATTTTCTCGAGCTGGATCGG
GGTGATCCGATGCCGAGTGGCTCAGAACTGGCGGACTAG

Upstream 100 bases:

>100_bases
CGAGTCGGCGCGTCGCTGATTTGCCCCCGAACCGCCGCAGGATCCCGTGCCCAAAATCGACCCCGAGCGCGTCGAGGTCA
GCAAGCCGCATCGCATCTGG

Downstream 100 bases:

>100_bases
CCGGGGTAGACGCGGTCAGGAAGCCTGAGCGATCAATGGGCGAACTGGGAAAGCGCACCGCCGGCGGCCAGGCCCAGAGC
GCAGAAGATGCCGAGATGGA

Product: hypothetical protein

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAVGAAVLLLLLLGAMLLPRTTGRLTSAPHGLAAAPAPPERPQDWRGDIDYRAMDSRLRAMMTDRSMQGLAVAVVEKGRL
SFVQGYGVTAEGGAPVDARTVFRWASLSKTVAGTLTARLAADGALSLQDPLSAFDTSLKLPGDAQVGLTLEQLLSQRTGL
GRNAYDGRLEDGEDPNVIRGSFAALKPVCPPGTCHTYQNIAYDTITEVIHARTGLDYAEAVKRRLFEPLGMKSTTFGEAG
LKSSAQWARPTRHGRALPFSDAYYHVPAAAGVNSTIVDLAIWMQAQMGLRPDVLSPSVLGEVQRSRVGTGRPYGRLNIAR
ELKGPGYGLGMRSFTYRGHDLVGHSGGVAGYRATMMFEPATRTGIVMLWNSDANLPFRYQAEFFDRVYGLPFTDFLELDR
GDPMPSGSELAD

Sequences:

>Translated_412_residues
MAVGAAVLLLLLLGAMLLPRTTGRLTSAPHGLAAAPAPPERPQDWRGDIDYRAMDSRLRAMMTDRSMQGLAVAVVEKGRL
SFVQGYGVTAEGGAPVDARTVFRWASLSKTVAGTLTARLAADGALSLQDPLSAFDTSLKLPGDAQVGLTLEQLLSQRTGL
GRNAYDGRLEDGEDPNVIRGSFAALKPVCPPGTCHTYQNIAYDTITEVIHARTGLDYAEAVKRRLFEPLGMKSTTFGEAG
LKSSAQWARPTRHGRALPFSDAYYHVPAAAGVNSTIVDLAIWMQAQMGLRPDVLSPSVLGEVQRSRVGTGRPYGRLNIAR
ELKGPGYGLGMRSFTYRGHDLVGHSGGVAGYRATMMFEPATRTGIVMLWNSDANLPFRYQAEFFDRVYGLPFTDFLELDR
GDPMPSGSELAD
>Mature_411_residues
AVGAAVLLLLLLGAMLLPRTTGRLTSAPHGLAAAPAPPERPQDWRGDIDYRAMDSRLRAMMTDRSMQGLAVAVVEKGRLS
FVQGYGVTAEGGAPVDARTVFRWASLSKTVAGTLTARLAADGALSLQDPLSAFDTSLKLPGDAQVGLTLEQLLSQRTGLG
RNAYDGRLEDGEDPNVIRGSFAALKPVCPPGTCHTYQNIAYDTITEVIHARTGLDYAEAVKRRLFEPLGMKSTTFGEAGL
KSSAQWARPTRHGRALPFSDAYYHVPAAAGVNSTIVDLAIWMQAQMGLRPDVLSPSVLGEVQRSRVGTGRPYGRLNIARE
LKGPGYGLGMRSFTYRGHDLVGHSGGVAGYRATMMFEPATRTGIVMLWNSDANLPFRYQAEFFDRVYGLPFTDFLELDRG
DPMPSGSELAD

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=361, Percent_Identity=25.207756232687, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 44435; Mature: 44304

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGAAVLLLLLLGAMLLPRTTGRLTSAPHGLAAAPAPPERPQDWRGDIDYRAMDSRLRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
MMTDRSMQGLAVAVVEKGRLSFVQGYGVTAEGGAPVDARTVFRWASLSKTVAGTLTARLA
HHHCCCCCCEEEEEECCCCEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADGALSLQDPLSAFDTSLKLPGDAQVGLTLEQLLSQRTGLGRNAYDGRLEDGEDPNVIRG
CCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEC
SFAALKPVCPPGTCHTYQNIAYDTITEVIHARTGLDYAEAVKRRLFEPLGMKSTTFGEAG
CHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
LKSSAQWARPTRHGRALPFSDAYYHVPAAAGVNSTIVDLAIWMQAQMGLRPDVLSPSVLG
CCCCCHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
EVQRSRVGTGRPYGRLNIARELKGPGYGLGMRSFTYRGHDLVGHSGGVAGYRATMMFEPA
HHHHHHCCCCCCCCCEEHHHHHCCCCCCCCCHHEEECCCEECCCCCCCCCEEEEEEECCC
TRTGIVMLWNSDANLPFRYQAEFFDRVYGLPFTDFLELDRGDPMPSGSELAD
CCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVGAAVLLLLLLGAMLLPRTTGRLTSAPHGLAAAPAPPERPQDWRGDIDYRAMDSRLRA
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
MMTDRSMQGLAVAVVEKGRLSFVQGYGVTAEGGAPVDARTVFRWASLSKTVAGTLTARLA
HHHCCCCCCEEEEEECCCCEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADGALSLQDPLSAFDTSLKLPGDAQVGLTLEQLLSQRTGLGRNAYDGRLEDGEDPNVIRG
CCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEC
SFAALKPVCPPGTCHTYQNIAYDTITEVIHARTGLDYAEAVKRRLFEPLGMKSTTFGEAG
CHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
LKSSAQWARPTRHGRALPFSDAYYHVPAAAGVNSTIVDLAIWMQAQMGLRPDVLSPSVLG
CCCCCHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
EVQRSRVGTGRPYGRLNIARELKGPGYGLGMRSFTYRGHDLVGHSGGVAGYRATMMFEPA
HHHHHHCCCCCCCCCEEHHHHHCCCCCCCCCHHEEECCCEECCCCCCCCCEEEEEEECCC
TRTGIVMLWNSDANLPFRYQAEFFDRVYGLPFTDFLELDRGDPMPSGSELAD
CCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6795623; 7610040; 9278503; 7041115; 9819201; 10595535; 11478888; 12144785; 12526668 [H]