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The map label for this gene is luxQ [H]

Identifier: 16125949

GI number: 16125949

Start: 1877441

End: 1879123

Strand: Direct

Name: luxQ [H]

Synonym: CC_1705

Alternate gene names: 16125949

Gene position: 1877441-1879123 (Clockwise)

Preceding gene: 16125948

Following gene: 16125950

Centisome position: 46.74

GC content: 68.03

Gene sequence:

>1683_bases
ATGGGAACGGTGTTGCGGACATTCTGGACAAACCTGGCGGAGGACTATCGCCCGGCGGCGTTGTCGCGTCGCAAACAGGT
TCCACTGCGTCTTTTCGTGATTGTCACCCTCTGCGTGGCGGCCCTGATCCTCAAGAATATGCCGTTCCTGTTCGGCTGGT
CGGTCGCCTACCTCGTCGTCCAGATCTGTGAGCTCTATGCGCTCAAGCGGTTCATCAACGCCGCTGACCCGACCGACCGC
GTCTGGGTCAACCTCGTTTCCGATGTCGCCCTGGCCACGGTGTTCGGCTGGCTGGCCCTGCCGTTGTGGGAGATGGGCAC
GCCCGCCGGAGCCGCCGGTGCGATGCTGCTCTTGTCGGCCTCGATCTTCACCGCCCTGATGGGGGCTGAAGGCTGTATGG
TCGCGTTCATCAGCGGCGCGGGGCCGCACGTGGCCTATCTGTTCATCACGCCTCTGCTTGCGGGCGGCGGCGGCGATCCG
GTCTTGCCGTACTTCCTGATCGGCGGCGGGCTGTTCACCCTGACCATCGCCATGACCTTCCTATGGTCGCACCGGGCGAT
GAAGGCCGAGCGGGAGGCGCGACGCGCCGCCGAGGCCCAAGTGGCCGCACGTTCGGCCCTGATCGCCATGGTCAGTCACG
AACTGCGAACGCCGATCAACGCCATCGTCAATGGCGCTGGACGCTTGGACGCGGGCAGCGCCGGTCTCATCGCCGATGCG
GGTCGGATGATGCGCACCCTGCTCAACGACCTGTTGGATCTGTCCAAGATCGAGGCCGGCCGCATGGGCGTCGAGATGGT
GGACCACGACCTGCGGGCTCAGGTGTCCGATGCCGTCGATTTCTGGCGCGGGGCGGCCGAGGCCAAGGGGGTGACCCTGA
CCCTGACCGGCGCCGAGCGCCTGCCGCGCTGGGTGCGGGGCGATCCCATGCGTCTGCGGCAGGTGCTCAACAACCTGATC
AGCAATGCCGTGAAGTTCACGACGGAAGGCGGAATCACCGTCGACGTTCGGCCAGTCGCCAGCGGGGCGGCGGCCGTGGA
GATCGAGGTCCGGGACACCGGACCGGGCCTCACCGAGGCGCAGATCATCCGGCTGTTCGATCCCTACGAACAGCTTGGCA
GCGAGACCGCGCGGAACTTCGGCGGCACGGGTCTTGGCCTGGCGATCAGTCGCGACCTTGCGCGTCTGATGGGTGGCGAG
CTCGCCGCCAGCTCTGCGCCGGAGGGCGGCGCGCGGTTCGTCCTGCGCCTGCCGACCCCGGCGGGCGCCGAGCCGACGAT
CCAGGCGCTTGCCGAAGAGCAGGACCTCGTGCTGGCGCCACGCTTGGACGCGCCGCGGATCCTGGTCGTCGACGACCATG
ACATCAACCGGCGCACCTTGCGCGGGATTCTGGAGGCGTTCGGGGCCGTCGTCGATGTCGCCGAGGATGCGCTGAGCGCT
CTGGCGGTGTGCGAAGACCAGCGCTTCGACGCCATCGTGATGGATGTGCGCATGCCGGGCATGGACGGGCTGGAGGCGAC
CCGCCGGCTCCGCGCGGCGGGCCTCAATCGTCAGACGCCCGTGGTGGCGGTCACCGGCGCGGTCTCGGACGACGAGGTCG
CGGCCTGTCGCGATGCGGGCATGACCGCCTGTGTCGCCAAACCTGTGAGCGCCCGCGAGCTTTATGCCGCCTTGTTCGCC
TGA

Upstream 100 bases:

>100_bases
GCCGCCGGGGGCATTGCGTTAGGGCGCTTTCGGGCGGTTCGATAGCTTACGCTTGAACCTAACGCGATCTAAACTCGGGC
AGACTGGGTGGCGCGTCCAG

Downstream 100 bases:

>100_bases
GGACAGCGTTAGCGCCTGACGATCGGCGGCTTCTTCACTAGAAATGGATGCGGCGCTGCGAGTCGGCGCGTCGCTGATTT
GCCCCCGAACCGCCGCAGGA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MGTVLRTFWTNLAEDYRPAALSRRKQVPLRLFVIVTLCVAALILKNMPFLFGWSVAYLVVQICELYALKRFINAADPTDR
VWVNLVSDVALATVFGWLALPLWEMGTPAGAAGAMLLLSASIFTALMGAEGCMVAFISGAGPHVAYLFITPLLAGGGGDP
VLPYFLIGGGLFTLTIAMTFLWSHRAMKAEREARRAAEAQVAARSALIAMVSHELRTPINAIVNGAGRLDAGSAGLIADA
GRMMRTLLNDLLDLSKIEAGRMGVEMVDHDLRAQVSDAVDFWRGAAEAKGVTLTLTGAERLPRWVRGDPMRLRQVLNNLI
SNAVKFTTEGGITVDVRPVASGAAAVEIEVRDTGPGLTEAQIIRLFDPYEQLGSETARNFGGTGLGLAISRDLARLMGGE
LAASSAPEGGARFVLRLPTPAGAEPTIQALAEEQDLVLAPRLDAPRILVVDDHDINRRTLRGILEAFGAVVDVAEDALSA
LAVCEDQRFDAIVMDVRMPGMDGLEATRRLRAAGLNRQTPVVAVTGAVSDDEVAACRDAGMTACVAKPVSARELYAALFA

Sequences:

>Translated_560_residues
MGTVLRTFWTNLAEDYRPAALSRRKQVPLRLFVIVTLCVAALILKNMPFLFGWSVAYLVVQICELYALKRFINAADPTDR
VWVNLVSDVALATVFGWLALPLWEMGTPAGAAGAMLLLSASIFTALMGAEGCMVAFISGAGPHVAYLFITPLLAGGGGDP
VLPYFLIGGGLFTLTIAMTFLWSHRAMKAEREARRAAEAQVAARSALIAMVSHELRTPINAIVNGAGRLDAGSAGLIADA
GRMMRTLLNDLLDLSKIEAGRMGVEMVDHDLRAQVSDAVDFWRGAAEAKGVTLTLTGAERLPRWVRGDPMRLRQVLNNLI
SNAVKFTTEGGITVDVRPVASGAAAVEIEVRDTGPGLTEAQIIRLFDPYEQLGSETARNFGGTGLGLAISRDLARLMGGE
LAASSAPEGGARFVLRLPTPAGAEPTIQALAEEQDLVLAPRLDAPRILVVDDHDINRRTLRGILEAFGAVVDVAEDALSA
LAVCEDQRFDAIVMDVRMPGMDGLEATRRLRAAGLNRQTPVVAVTGAVSDDEVAACRDAGMTACVAKPVSARELYAALFA
>Mature_559_residues
GTVLRTFWTNLAEDYRPAALSRRKQVPLRLFVIVTLCVAALILKNMPFLFGWSVAYLVVQICELYALKRFINAADPTDRV
WVNLVSDVALATVFGWLALPLWEMGTPAGAAGAMLLLSASIFTALMGAEGCMVAFISGAGPHVAYLFITPLLAGGGGDPV
LPYFLIGGGLFTLTIAMTFLWSHRAMKAEREARRAAEAQVAARSALIAMVSHELRTPINAIVNGAGRLDAGSAGLIADAG
RMMRTLLNDLLDLSKIEAGRMGVEMVDHDLRAQVSDAVDFWRGAAEAKGVTLTLTGAERLPRWVRGDPMRLRQVLNNLIS
NAVKFTTEGGITVDVRPVASGAAAVEIEVRDTGPGLTEAQIIRLFDPYEQLGSETARNFGGTGLGLAISRDLARLMGGEL
AASSAPEGGARFVLRLPTPAGAEPTIQALAEEQDLVLAPRLDAPRILVVDDHDINRRTLRGILEAFGAVVDVAEDALSAL
AVCEDQRFDAIVMDVRMPGMDGLEATRRLRAAGLNRQTPVVAVTGAVSDDEVAACRDAGMTACVAKPVSARELYAALFA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=33.3333333333333, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081816, Length=386, Percent_Identity=33.6787564766839, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI48994928, Length=386, Percent_Identity=32.3834196891192, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=33.7254901960784, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=34.9794238683128, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=28.6821705426357, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=266, Percent_Identity=30.0751879699248, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=33.0434782608696, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=28.3842794759825, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=28.755364806867, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=28.448275862069, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788191, Length=114, Percent_Identity=35.0877192982456, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=113, Percent_Identity=30.9734513274336, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59687; Mature: 59556

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVLRTFWTNLAEDYRPAALSRRKQVPLRLFVIVTLCVAALILKNMPFLFGWSVAYLVV
CCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QICELYALKRFINAADPTDRVWVNLVSDVALATVFGWLALPLWEMGTPAGAAGAMLLLSA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SIFTALMGAEGCMVAFISGAGPHVAYLFITPLLAGGGGDPVLPYFLIGGGLFTLTIAMTF
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LWSHRAMKAEREARRAAEAQVAARSALIAMVSHELRTPINAIVNGAGRLDAGSAGLIADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHH
GRMMRTLLNDLLDLSKIEAGRMGVEMVDHDLRAQVSDAVDFWRGAAEAKGVTLTLTGAER
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHH
LPRWVRGDPMRLRQVLNNLISNAVKFTTEGGITVDVRPVASGAAAVEIEVRDTGPGLTEA
CCHHHCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCHH
QIIRLFDPYEQLGSETARNFGGTGLGLAISRDLARLMGGELAASSAPEGGARFVLRLPTP
HHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEECCCC
AGAEPTIQALAEEQDLVLAPRLDAPRILVVDDHDINRRTLRGILEAFGAVVDVAEDALSA
CCCCHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAVCEDQRFDAIVMDVRMPGMDGLEATRRLRAAGLNRQTPVVAVTGAVSDDEVAACRDAG
HHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHCC
MTACVAKPVSARELYAALFA
CHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
GTVLRTFWTNLAEDYRPAALSRRKQVPLRLFVIVTLCVAALILKNMPFLFGWSVAYLVV
CCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QICELYALKRFINAADPTDRVWVNLVSDVALATVFGWLALPLWEMGTPAGAAGAMLLLSA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SIFTALMGAEGCMVAFISGAGPHVAYLFITPLLAGGGGDPVLPYFLIGGGLFTLTIAMTF
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LWSHRAMKAEREARRAAEAQVAARSALIAMVSHELRTPINAIVNGAGRLDAGSAGLIADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHH
GRMMRTLLNDLLDLSKIEAGRMGVEMVDHDLRAQVSDAVDFWRGAAEAKGVTLTLTGAER
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHH
LPRWVRGDPMRLRQVLNNLISNAVKFTTEGGITVDVRPVASGAAAVEIEVRDTGPGLTEA
CCHHHCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCHH
QIIRLFDPYEQLGSETARNFGGTGLGLAISRDLARLMGGELAASSAPEGGARFVLRLPTP
HHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEECCCC
AGAEPTIQALAEEQDLVLAPRLDAPRILVVDDHDINRRTLRGILEAFGAVVDVAEDALSA
CCCCHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAVCEDQRFDAIVMDVRMPGMDGLEATRRLRAAGLNRQTPVVAVTGAVSDDEVAACRDAG
HHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHCC
MTACVAKPVSARELYAALFA
CHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA